【レポートの概要（一部）】
1 Table of Contents
1 Table of Contents 5
1.1 List of Tables 7
1.2 List of Figures 8
2 Monoclonal Antibodies Market in Breast Cancer to 2019 – Introduction 9
2.1 Symptoms 9
2.2 Etiology 9
2.3 Epidemiology 10
2.4 Pathophysiology 10
2.5 Diagnosis 11
2.6 Prognosis and Disease Staging 11
2.6.1 Classification 13
2.7 Treatment Options 13
2.7.1 Surgery and Radiation Therapy 13
2.7.2 Chemotherapy 14
2.7.3 Hormonal Therapies 15
2.7.4 Targeted Therapies 15
2.7.5 Resistance to Pharmacological Therapies 16
2.7.6 Treatment Guidelines 17
2.7.7 Measuring the Effectiveness of Treatment 19
3 Marketed Products 20
3.1 Herceptin (Trastuzumab) – Hoffmann La Roche 20
3.2 Avastin (Bevacizumab) – Hoffmann La Roche 23
3.3 Kadcyla (Trastuzumab Emtansine) – Hoffmann La Roche 25
3.4 Perjeta (Pertuzumab) – Hoffmann La Roche 26
3.5 Xgeva (denosumab) – Amgen 27
3.6 Heat Map for Marketed Products 28
3.7 Conclusion 30
4 Pipeline for Breast Cancer Monoclonal Antibody Therapeutics 31
4.1 Overall Pipeline 32
4.2 Mechanisms of Action 34
4.3 Clinical Trials 37
4.3.1 Attrition Rate 37
4.3.2 Clinical Trial Size 38
4.3.3 Duration 40
4.3.4 Clinical Trial End-points 42
4.4 Promising Drug Candidates in the Pipeline 44
4.4.1 CDX-011 (glembatumumab vedotin) – Celldex Therapeutics 44
4.4.2 Metmab (onartuzumab) – Hoffman La Roche 44
4.4.3 Hu3S193 – Recepta Biopharma 44
4.4.4 MM-121 – Merrimack Pharmaceuticals 45
4.4.5 IMC-18F1 (Icrucumab) – Eli Lilly 45
4.4.6 Rexomun (Ertumaxomab) – Fresenius Biotech 45
4.4.7 Medi-573 (Dusigitumab) – Medimmune 45
4.4.8 MK-0646 (Dalotuzumab) – Merck and Co 46
4.4.9 LY3012217 (Cixutumumab) – Eli Lilly 46
4.5 Conclusion 46
5 Market Forecast to 2019 48
5.1 Global 48
5.1.1 Treatment Usage Patterns 48
5.1.2 Market Size 49
5.2 US 50
5.2.1 Treatment Usage Patterns 50
5.2.2 Market Size 51
5.3 Canada 52
5.3.1 Treatment Usage Patterns 52
5.3.2 Market Size 53
5.4 Europe 54
5.4.1 Treatment Usage Patterns 54
5.4.2 Annual Cost of Therapy 55
5.4.3 Market Size 56
5.5 Japan 57
5.5.1 Treatment Usage Patterns 57
5.5.2 Market Size 58
5.6 Drivers and Barriers 59
5.6.1 Drivers 59
5.6.2 Barriers 59
6 Deals and Strategic Consolidations 60
6.1 R&D Licensing Agreements 60
6.1.1 Key Licensing Deals 63
6.2 Co-development Agreements 65
6.2.1 Key Deals 65
7 Appendix 68
7.1 References 68
7.2 References for Heat Map 73
7.3 All Pipeline Products, by Phase 74
7.3.1 Discovery 74
7.3.2 Preclinical 77
7.3.3 IND/CTA Filed and Phase I 89
7.3.4 Phase II 95
7.3.5 Phase III and Pre-Registration 102
7.4 Market Definitions 104
7.5 Abbreviations 105
7.6 Tabular Forecast Data 106
7.6.1 Global 106
7.6.2 US 106
7.6.3 Canada 106
7.6.4 UK 107
7.6.5 France 107
7.6.6 Germany 107
7.6.7 Italy 107
7.6.8 Spain 108
7.6.9 Japan 108
7.7 Research Methodology 109
7.7.1 Coverage 109
7.7.2 Secondary Research 109
7.8 Therapeutic Landscape 110
7.9 Epidemiology-Based Forecasting 110
7.10 Market Size by Geography 111
7.11 Geographical Landscape 112
7.12 Pipeline Analysis 112
7.13 Competitive Landscape 112
7.13.1 Expert Panel Validation 112
7.14 Contact Us 112
7.15 Disclaimer 112
【レポート販売概要】
■ タイトル：Monoclonal Antibodies Market in Breast Cancer to 2019 – Strong Uptake of Novel HER-2 Targeted Therapies to Drive Robust Growth■ 発行日：2013年10月31日
■ 調査会社：GBI Research
■ 商品コード：GBIR403170039
■ 調査対象地域：グローバル
- 世界の非接触センシング装置市場動向（2012-2016）TechNavio's analysts forecast the Global Touchless Sensing Equipment market to grow at a CAGR of 32.2 percent over the period 2012-2016. One of the key factors contributing to this market growth is the growing need for high-level security in the Government sector. The Global Touchless Sensing Equipment market has also been witnessing rapid technological advancement. However, touchless sensing equi …
- 自動車ソーラーカーポート充電スタンド（SCCS）の世界市場2017-2021About Automotive Solar Carport Charging StationA solar carport is an electric end-use charging infrastructure that employs PV effect to convert solar energy incident upon the solar panels into electricity. Since the solar carport does not use power from the electricity grids (theoretically), it is a clean and efficient charging infrastructure for electric end-use implementation. Therefore, conside …
- アルミニウム鋳造の世界市場：アルミニウムダイカスト、アルミニウム金型鋳造About Aluminum Casting Casting is used for making geometrically complex parts using metals and cold setting materials. It is of two types: ferrous and non-ferrous. Aluminum, zinc, magnesium, and copper-based alloys are the most common non-ferrous metals used for casting. Aluminum cast components are used in the manufacturing of sub-assemblies of planes, vehicles, and trains. They are also used in …
- レーザー技術の世界市場予測（～2022年）：固体レーザー、液体レーザー、ガスレーザー“The overall laser technology market is expected to grow at a CAGR of 5.2%”The laser technology market is expected to reach USD 15.38 billion by 2022, growing at a CAGR of 5.2% between 2017 and 2022. Enhanced performance over the traditional material processing techniques is one of the major factors fueling the growth of this market. Moreover, the increasing demand from the healthcare sector and s …
- 内視鏡検査システムの世界市場：予測とディスカッション2016-2026Endoscopy for Medicine: Why You Cannot Afford to Overlook that Rising Market – Introducing Your Guide to its Sales Potential What is the future of endoscopic devices and their producers? Visiongain’s new report gives you that data and analysis, helping you explore developments, technology and revenue predictions for endoscopic applications in healthcare. Discover where that industry heads. Our inv …
- Osaka Gas Co., Ltd.：石油・ガスバリューチェーン分析レポート2013Osaka Gas Co., Ltd. Analysis Across the Oil and Gas Value Chain Report, 2013 Update Summary "Osaka Gas Co., Ltd." Analysis Across the Oil and Gas Value Chain is an essential source for data, analysis and strategic insight into “Osaka Gas Co., Ltd.”. The report provides key information relating to oil and gas assets of the company along with its operations across the value chain. The report examine …
- 自動車産業向けオートメーション製品の世界市場：PLM、センサー、DCS、PLC、MES、SCADAThe automotive industry has great scope for automation solutions because the dynamic nature of consumer demand requires improved safety standards in vehicles and the use of advanced technologies such as connected and automated cars. The growth of automation solutions in the automotive industry will be driven by the expansion of plant capacity in countries such as the US, China, Germany, Italy, and …
- 炭素回収・隔離の世界市場動向・予測（～2021）The global carbon capture & sequestration market is projected to reach USD 8.05 billion by 2021, at a CAGR of 13.6% from 2016 to 2021. This growth can be attributed to rising environmental concerns across the world and increasing demand for CO2-EOR techniques. The report segments the carbon capture & sequestration market based on services into capture, transport, and sequestration. The capture seg …
- M2Mビジネス事例：ソリューション、ビジネスモデル、ROI（Machine-to-Machine (M2M) Business Case: Solutions, Business Models, and ROI by Industry Vertical）The Machine-to-Machine (M2M) market is seen as the future for wireless revenue growth with various reports touting market size to reach 50 billion connections by 2020. However, the current market is still under 100 million connections. Since M2M is not the only service for telecom carriers, rather it is not their core service; strategies adopted for M2M cannot be studied on stand-alone basis. The …
- ブタジエン及びブタジエン誘導体の世界市場2017-2021About Butadiene and Its DerivativesButadiene is a type of petrochemical product used in the production of several derivatives, which are primarily used in making synthetic rubber, plastics, resins, and other polymers. Technavio’s analysts forecast the global butadiene and its derivatives market to grow at a CAGR of 10.16% during the period 2017-2021. [Covered in this report] The report covers the …
- Interim Storage Providing Necessary Leeway to Adopt Proper Spent Nuclear Fuel Management StrategyInterim Storage Providing Necessary Leeway to Adopt Proper Spent Nuclear Fuel Management Strategy Summary The ambiguity on the eventual treatment of Spent Nuclear Fuel (SNF) by most of the nuclear power countries stimulates the development of interim storage facilities. It provides sufficient time and storage capacity for the safe, reliable and cost effective management of SNF. Interim storage hel …
- 自動車シートベルト・プリテンショナーの世界市場About Automotive Seatbelt Pre-tensioners Seatbelt pre-tensioner, a passive safety system, is activated when an installed sensor detect a rapid deceleration during an accident. It is used to manage the occupant's energy in a crash by pulling the driver and front-seat passenger firmly into their seats, thereby reducing the occupant's load in a violent crash. Automotive seatbelt pre-tensioners tighte …
- オキシラン(エチレンオキシド)の国際貿易動向This report examines international trade and worldwide market trends pertaining to oxirane (ethylene oxide). The report will be of considerable interest primarily to relevant strategic planners, senior company officials and importers/exporters, since it features invaluable information on oxirane (ethylene oxide) export/import operations segmented by country and region. The report covers the 2007-2 …
- スマートフォン向け音声認識の世界市場2015-2019About voice recognition Voice recognition refers to an authentication technology where sounds, words, or phrases spoken by humans are changed into electrical signals and are converted into coding patterns and assigned meanings. Each human voice is different, and identical words can have different meanings if spoken with different inflections or in different contexts. Voice-based technology is divi …
- 世界のモバイル・ブロードバンド・モデム市場動向（2012-2016）TechNavio's analysts forecast the Global Mobile Broadband Modem Market to grow at a CAGR of 14.62 percent over the period 2012-2016. One of the key factors contributing to this market growth is the high adoption of mobile devices. The Global Mobile Broadband Modem Market has also been witnessing availability of 3G and 4G supporting modems. However, the increasing availability of mobile hotspot rou …
