【レポートの概要（一部）】
1 Table of Contents
1 Table of Contents 4
1.1 List of Tables 5
1.2 List of Figures 6
2 Introduction 7
2.1 Disease Introduction 7
2.2 Symptoms 8
2.3 Etiology 8
2.4 Pathophysiology 9
2.5 Diagnosis 9
2.6 Prognosis 10
2.7 Assessment of Disease Severity 10
2.8 Treatment 10
3 Marketed Products 12
3.1 Overview 12
3.2 Product Profiles 13
3.2.1 Pulmozyme (dornase alfa) – Genentech 13
3.2.2 Bronchitol (mannitol) – Pharmaxis 14
3.2.3 TOBI (tobramycin) – Novartis 15
3.2.4 TOBI Podhaler (tobramycin) – Novartis 16
3.2.5 Bramitob/Bethkis (tobramycin) – Chiesi Farmaceutici 17
3.2.6 Colobreathe (colistimethate sodium) – Forest Laboratories 17
3.2.7 Cayston (aztreonam) – Gilead Sciences 18
3.2.8 Kalydeco (ivacaftor) – Vertex Pharmaceuticals 19
3.2.9 Pancreatic Enzyme Replacement Therapies 20
3.2.10 Other Successful Products 21
3.3 Heat Map of Marketed Products 21
3.4 Conclusion 23
4 Developmental Pipeline 25
4.1 Overview 25
4.2 Mechanisms of Action in the Pipeline 27
4.3 Clinical Trials 30
4.3.1 Failure Rate 30
4.3.2 Clinical Trial Duration 31
4.3.3 Clinical Trial Size 32
4.4 Promising Pipeline Molecules 35
4.4.1 Lumacaftor (VX809) – Vertex Pharmaceuticals 35
4.4.2 Ataluren (PTC124) – PTC Therapeutics 37
4.4.3 Aeroquin (levofloxacin) – Aptalis Pharma 38
4.4.4 Arikace (amikacin liposomal) – Insmed 40
4.4.5 Other Promising Molecules 41
4.5 Heat Map of Pipeline Products 42
4.6 Conclusion 44
5 Market Forecast to 2019 45
5.1 Geographical Markets 45
5.1.1 Global Markets 46
5.1.2 North America 48
5.1.3 Top Five EU Countries 51
5.2 Drivers and Barriers 55
5.2.1 Drivers 55
5.2.2 Barriers 56
6 Strategic Consolidations 57
6.1 Major Co-Development Deals 57
6.2 Major Licensing Deals 60
7 Appendix 63
7.1 References 68
7.1.1 Marketed Product Heat Map References 70
7.1.2 Pipeline Product Heat Map References 71
7.2 Market Definition 71
7.3 Abbreviations 72
7.4 Methodology 72
7.5 Coverage 72
7.6 Secondary Research 73
7.7 Therapeutic Landscape 73
7.8 Epidemiology-Based Forecasting 74
7.9 Market Size by Geography 75
7.10 Geographical Landscape 75
7.11 Pipeline Analysis 76
7.12 Competitive Landscape 76
7.12.1 Expert Panel Validation 76
7.13 Contact Us 76
7.14 Disclaimer 76
【レポート販売概要】
■ タイトル：主要先進国における嚢胞性線維症（CF）治療薬市場（～2019）■ 英文：Cystic Fibrosis Therapeutics in Major Developed Markets to 2019 - CFTR Modulators Initiate Drive towards Personalized Treatment and Market Growth
■ 発行日：2014年2月7日
■ 調査会社：GBI Research
■ 商品コード：GBIR403172470
■ 調査対象地域：グローバル
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