【レポートの概要（一部）】
1 Table of Contents
1 Table of Contents 6
1.1 List of Tables 15
1.2 List of Figures 19
2 Introduction 22
2.1 Overview 22
2.2 Catalyst 22
3 Disease Overview 24
3.1 Anatomy and Physiology 24
3.2 Pathophysiology 25
3.3 Etiology 25
3.3.1 Causes 25
3.3.2 Risk Factors 28
3.4 Clinical Presentation 30
3.4.1 Symptoms 30
3.4.2 Diagnosis 30
3.4.3 Clinical Outcomes 33
3.5 Epidemiology 37
3.5.1 Resistant Hypertension 37
3.5.2 Uncontrolled Hypertension 41
3.5.3 Heart Failure 43
3.6 Economic Impact 45
3.6.1 Overview 45
3.6.2 US 46
3.6.3 European Union 48
3.6.4 Asia-Pacific 49
3.6.5 South America 51
4 Marketed Products 53
4.1 Overview 53
4.2 Market Share 54
4.2.1 US Market Share, 2013 and 2016 54
4.2.2 France Market Share, 2013 and 2016 56
4.2.3 Germany Market Share, 2013 and 2016 57
4.2.4 Italy Market Share, 2013 and 2016 59
4.2.5 Spain Market Share, 2013 and 2016 60
4.2.6 UK Market Share, 2013 and 2016 62
4.2.7 Japan Market Share, 2013 and 2016 64
4.2.8 Brazil Market Share, 2013 and 2016 65
4.2.9 India Market Share, 2013 and 2016 66
4.2.10 China Market Share, 2013 and 2016 67
4.3 Allegra Renal Denervation System (Terumo/AngioCare) 68
4.3.1 Overview 68
4.3.2 Safety and Efficacy 69
4.3.3 SWOT Analysis 70
4.4 EnligHTN Renal Denervation System (St. Jude Medical) 71
4.4.1 Overview 71
4.4.2 Safety and Efficacy 72
4.4.3 SWOT Analysis 74
4.5 OneShot Renal Denervation System (Covidien) 75
4.5.1 Overview 75
4.5.2 Safety and Efficacy 76
4.5.3 SWOT Analysis 77
4.6 Paradise Renal Denervation System (ReCor Medical) 78
4.6.1 Overview 78
4.6.2 Safety and Efficacy 79
4.6.3 SWOT Analysis 80
4.7 Symplicity Renal Denervation System (Medtronic) 81
4.7.1 Overview 81
4.7.2 Safety and Efficacy 82
4.7.3 SWOT Analysis 86
4.8 Vessix Renal Denervation System (Boston Scientific Corporation) 87
4.8.1 Overview 87
4.8.2 Safety and Efficacy 88
4.8.3 SWOT Analysis 89
5 Unmet Needs 90
5.1 Overview 90
5.1.1 Intervention to Determine Renal Denervation Efficacy 90
5.1.2 Investigation of Renal Nerve Regeneration 92
5.1.3 Ambulatory Versus Office-Based Blood Pressure Readings 93
5.1.4 Effect of Renal Denervation on Prescription Antihypertensive Medication 98
5.1.5 Expanded Indications for Renal Denervation Systems 100
5.1.6 Effect of Renal Denervation on the Adventitial Layer 103
5.1.7 Repeat Renal Denervation Procedures 106
5.1.8 Long-Term Clinical Trial Data 107
6 Pipeline Products 108
6.1 Overview 108
6.2 Beta-Cath System (Best Medical International) 108
6.2.1 Overview 108
6.2.2 Safety and Efficacy 108
6.2.3 SWOT Analysis 109
6.3 Bullfrog MicroFusion Catheter (Mercator MedSystems) 110
6.3.1 Overview 110
6.3.2 Safety and Efficacy 111
6.3.3 SWOT Analysis 111
6.4 Chemical Denervation System (Kipprokration Hospital) 112
6.4.1 Overview 112
6.4.2 Safety and Efficacy 112
6.4.3 SWOT Analysis 113
6.5 Cryoablation System (Cryomend) 113
6.5.1 Overview 113
6.5.2 Safety and Efficacy 114
6.5.3 SWOT Analysis 114
6.6 Kona Surround Sound System (Kona Medical) 115
6.6.1 Overview 115
6.6.2 Safety and Efficacy 116
6.6.3 SWOT Analysis 117
6.7 Magnetic Nanoparticles (ApexNano) 118
6.7.1 Overview 118
6.7.2 Safety and Efficacy 118
6.7.3 SWOT Analysis 119
6.8 Perivascular Renal Denervation System (Ablative Solutions) 120
6.8.1 Overview 120
6.8.2 Safety and Efficacy 120
6.8.3 SWOT Analysis 121
6.9 Sound 360 Ultrasonic Renal Denervation System (Sound Interventions) 122
6.9.1 Overview 122
6.9.2 Safety and Efficacy 123
6.9.3 SWOT Analysis 124
6.10 Symple Surgical System (Symple Surgical) 125
6.10.1 Overview 125
6.10.2 Safety and Efficacy 125
6.10.3 SWOT Analysis 125
6.11 Tivus System (Cardiosonic) 126
6.11.1 Overview 126
6.11.2 Safety and Efficacy 127
6.11.3 SWOT Analysis 128
6.12 Celsius ThermoCool System (Cordis/Johnson & Johnson) 129
6.12.1 Overview 129
6.12.2 Safety and Efficacy 129
6.12.3 SWOT Analysis 130
6.13 Northwind Medical System (Northwind Medical) 131
6.13.1 Overview 131
6.13.2 Safety and Efficacy 131
6.13.3 SWOT Analysis 131
6.14 Verve Medical System (Verve Medical) 132
6.14.1 Overview 132
6.14.2 Safety and Efficacy 132
6.14.3 SWOT Analysis 133
7 Clinical Trial Analysis 134
7.1 Overview 134
7.2 Clinical Trial Timeline 135
7.3 Clinical Trial Results 145
7.4 Analysis of Trials to Watch 149
7.4.1 Longer Follow-Up 149
7.4.2 Uncontrolled Hypertension 149
7.4.3 Second-Generation Devices 150
7.4.4 Additional Indications 153
8 Industry Overview 154
8.1 Procedure Trends 154
8.1.1 Global 154
8.1.2 United States 158
8.1.3 European Union 159
8.1.4 South America 162
8.1.5 Asia-Pacific 163
8.2 Market Access 164
8.3 Reimbursement Trends 165
8.3.1 Overview 165
8.3.2 United States 165
8.3.3 European Union 167
8.3.4 Asia-Pacific 173
8.3.5 South America 175
8.4 Regulatory Issues/Recalls 175
8.5 Added Indications 176
8.6 Mergers and Acquisitions/Key Partnerships 178
8.6.1 Overview 178
8.6.2 Boston Scientific Acquires Vessix Vascular 179
8.6.3 Covidien Acquires Maya Medical 179
8.6.4 Medtronic Acquires Ardian 180
8.6.5 Terumo Corporation Partners With AngioCare Medical Technology 180
9 Current and Future Players 181
9.1 Trends in Corporate Strategy 181
9.2 Company Profiles 182
9.2.1 Ablative Solutions 182
9.2.2 ApexNano 185
9.2.3 Best Medical International 188
9.2.4 Boston Scientific Corporation 190
9.2.5 Cardiosonic 193
9.2.6 Covidien 196
9.2.7 Cordis Corporation and Johnson & Johnson 199
9.2.8 Cryomend 202
9.2.9 Kona Medical 204
9.2.10 Medtronic 207
9.2.11 Mercator MedSystems 210
9.2.12 Northwind Medical 213
9.2.13 ReCor Medical 215
9.2.14 Sound Interventions 218
9.2.15 St. Jude Medical 221
9.2.16 Symple Surgical 224
9.2.17 Terumo Corporation 226
9.2.18 Verve Medical 229
10 Market Drivers and Opportunities 232
10.1 Market Drivers 232
10.1.1 Growing Global Prevalence and Cost of Hypertension 232
10.1.2 Significant and Sustained Reductions in Office-Based Blood Pressure 233
10.1.3 Growing Clinical Evidence of Efficacy in Other Indications 234
10.1.4 Potential for Outpatient Procedure 235
10.1.5 Positive Results in Moderate Hypertensive Patients 236
10.2 Market Opportunities 237
10.2.1 Expanding Indications 237
10.2.2 Competitive Cost Structure 239
10.2.3 Low-Profile Catheters 240
10.2.4 Catheters for Radial Access 243
10.2.5 Circumferential Ablation 245
10.2.6 Mapping System 246
10.2.7 Clinical Trials in Key Countries 246
10.2.8 Incorporate Renal Denervation Catheters into Sales of Other Cardiology Products 248
10.3 Market Threats 249
10.3.1 Ambulatory Blood Pressure Readings 249
10.3.2 Results of the Symplicity HTN-3 Trial 250
10.3.3 Extent of Clinical Trial Data 251
10.3.4 Radiofrequency Ablation Thermal Damage 252
10.3.5 Degree of Patient Pain 253
10.3.6 Inpatient Procedure 254
10.3.7 Carotid Baroreceptor Stimulation 255
10.3.8 External Systems 258
10.3.9 Micro-Infusion Systems 259
10.3.10 White-Coat Effect 259
10.3.11 Entrance of Cordis Into the Market 260
10.3.12 New Referral Pattern 261
11 Country Outlooks and Forecasts 263
11.1 Major Markets Overview 263
11.2 United States 265
11.3 France 267
11.4 Germany 269
11.5 Italy 271
11.6 Spain 273
11.7 United Kingdom 275
11.8 Japan 277
11.9 Brazil 279
11.10 India 281
11.11 China 283
12 Appendix 284
12.1 Bibliography 284
12.2 Abbreviations 300
12.3 Report Methodology 303
12.3.1 Overview 303
12.3.2 Coverage 303
12.3.3 Primary Research 303
12.3.4 Secondary Research 304
12.3.5 Forecasting Methodology 305
12.4 Key Opinion Leaders Included in this Study 306
12.5 About the Authors 307
12.5.1 Joseph A. Gregory, Analyst, Surgical Devices 307
12.5.2 Derek Archila, MBA, Director of Research and Analysis, Medical Devices 307
12.6 Global Head of Healthcare 308
12.6.1 Bonnie Bain, Ph.D., Global Head of Healthcare 308
12.7 About MediPoint 309
12.8 About GlobalData 309
12.9 Disclaimer 309
【レポート販売概要】
■ タイトル：腎除神経（腎デナベーション）：グローバル市場分析と予測■ 英文：MediPoint: Renal Denervation - Global Analysis and Market Forecasts
■ 発行日：2013年10月31日
■ 調査会社：GlobalData
■ 商品コード：GDATA403162526
■ 調査対象地域：グローバル
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