【レポートの概要（一部）】
1 Table of Contents
1 Table of Contents 10
1.1 List of Tables 17
1.2 List of Figures 23
2 Introduction 25
2.1 Catalyst 25
2.2 Related Reports 26
2.3 Upcoming Related Reports 26
3 Disease Overview 27
3.1 Etiology and Pathophysiology 27
3.1.1 Etiology 27
3.1.2 Pathophysiology and Histology 27
3.1.3 NSCLC Biomarkers 28
3.1.4 Quality of Life 29
3.2 Symptoms 30
4 Epidemiology 31
4.1 Risk Factors and Comorbidities 32
4.1.1 Smokers are more likely to have lung cancer than non-smokers 33
4.1.2 Long-term exposure to radon increases the risk of lung cancer 35
4.1.3 Family history of any cancer increases lung cancer risk 35
4.1.4 TB increases the risk of lung cancer and increases mortality risk 35
4.1.5 COPD is a comorbidity that reduces lung cancer survival 36
4.1.6 Lung cancer screening programs may not be beneficial 36
4.1.7 Stage at diagnosis significantly impacts the survival of lung cancer cases 37
4.2 Global Trends 38
4.2.1 US 41
4.2.2 France 46
4.2.3 Germany 47
4.2.4 Italy 49
4.2.5 Spain 51
4.2.6 UK 53
4.2.7 Japan 54
4.2.8 China 56
4.2.9 India 58
4.3 Forecast Methodology 60
4.3.1 Sources Used 61
4.3.2 Sources Not Used 66
4.3.3 Forecast Assumptions and Methods 67
4.4 Epidemiology Forecast (2012-2022) 69
4.4.1 Incident/Prevalent Cases of NSCLC 69
4.4.2 Age-Specific Incident Cases of NSCLC 71
4.4.3 Sex-Specific Incident Cases of NSCLC 72
4.4.4 Age-Standardized Incidence Rates of NSCLC 74
4.4.5 Segmentation of NSCLC Incident Cases 75
4.5 Discussion 83
4.5.1 Limitations of the Analysis 84
4.5.2 Strengths of the Analysis 85
5 Disease Management 86
5.1 Treatment Overview 86
5.1.1 Diagnosis 87
5.1.2 Clinical Staging 88
5.1.3 Screening and Early Detection 89
5.1.4 Localized Procedures and Therapies 91
5.1.5 Systemic Chemotherapy 91
5.1.6 Targeted Therapy 92
5.2 US 94
5.2.1 Diagnosis 94
5.2.2 Clinical Practice 95
5.3 France 97
5.3.1 Diagnosis 97
5.3.2 Clinical Practice 98
5.4 Germany 99
5.4.1 Diagnosis 99
5.4.2 Clinical Practice 100
5.5 Italy 102
5.5.1 Diagnosis 102
5.5.2 Clinical Practice 102
5.6 Spain 103
5.6.1 Diagnosis 103
5.6.2 Clinical Practice 104
5.7 UK 105
5.7.1 Diagnosis 105
5.7.2 Clinical Practice 105
5.8 Japan 107
5.8.1 Diagnosis 107
5.8.2 Clinical Practice 107
5.9 China 109
5.9.1 Diagnosis 109
5.9.2 Clinical Practice 109
5.10 India 110
5.10.1 Diagnosis 110
5.10.2 Clinical Practice 111
6 Competitive Assessment 113
6.1 Overview 113
6.2 Strategic Competitor Assessment 114
6.3 Product Profiles – Major Brands, Chemotherapies 116
6.3.1 Alimta (pemetrexed disodium) 116
6.3.2 Abraxane (nab-paclitaxel) 121
6.4 Product Profiles – Major Brands, Targeted Therapies 125
6.4.1 Iressa (gefitinib) 125
6.4.2 Tarceva (erlotinib hydrochloride) 130
6.4.3 Xalkori (crizotinib) 136
6.4.4 Avastin (bevacizumab) 141
7 Opportunity and Unmet Need 145
7.1 Overview 145
7.2 Improved Overall Survival and Less Toxicity 147
7.3 Treatments for Patients with Acquired TKI Resistance 147
7.4 Better Treatment Options for Squamous Patients 148
7.5 Preventing Relapse or Recurrence 149
7.6 More Efficacious Second-Line Therapies 149
7.7 Increased Availability of Mutation Testing 150
7.8 More Cost-Effective Therapies 150
7.9 Unmet Needs Gap Analysis 151
8 Pipeline Assessment 154
8.1 Overview 154
8.2 Clinical Trial Mapping 155
8.2.1 Clinical Trials by Country 155
8.3 Clinical Trials by Phase and Trial Status 156
8.4 Promising Drugs in Clinical Development 157
8.4.1 onartuzumab (MetMab) 160
8.4.2 necitumumab (IMC-11F8) 167
8.4.3 ramucirumab (IMC-1121B) 173
8.4.4 custirsen (OGX-011) 178
8.4.5 ganetespib (STA-9090) 184
8.4.6 nintedanib (BIBF1120) 191
8.4.7 afatinib (BIBW-2992) 196
8.4.8 dacomitinib (PF-00299804) 202
8.4.9 LDK378 207
8.4.10 Yervoy (ipilimumab) 213
8.4.11 nivolumab (BMS936558) 218
8.4.12 GSK1572932A (MAGE-A3 Cancer Immunotherapeutic) 225
8.4.13 Halaven (eribulin mesylate) 230
9 Current and Future Players 234
9.1 Overview 234
9.2 Trends in Corporate Strategy 237
9.3 Company Profiles 238
9.3.1 Roche/Genentech 238
9.3.2 Pfizer 241
9.3.3 Bristol-Myers Squibb 243
9.3.4 Eli Lilly 245
9.3.5 Boehringer Ingelheim 248
9.3.6 Novartis 250
10 Market Outlook 251
10.1 Global Markets 251
10.1.1 Forecast 251
10.1.2 Drivers and Barriers – Global Issues 255
10.2 United States 258
10.2.1 Forecast 258
10.2.2 Key Events 261
10.2.3 Drivers and Barriers 262
10.3 France 265
10.3.1 Forecast 265
10.3.2 Key Events 268
10.3.3 Drivers and Barriers 269
10.4 Germany 271
10.4.1 Forecast 271
10.4.2 Key Events 274
10.4.3 Drivers and Barriers 275
10.5 Italy 277
10.5.1 Forecast 277
10.5.2 Key Events 280
10.5.3 Drivers and Barriers 281
10.6 Spain 283
10.6.1 Forecast 283
10.6.2 Key Events 285
10.6.3 Drivers and Barriers 286
10.7 United Kingdom 288
10.7.1 Forecast 288
10.7.2 Key Events 292
10.7.3 Drivers and Barriers 293
10.8 Japan 295
10.8.1 Forecast 295
10.8.2 Key Events 299
10.8.3 Drivers and Barriers 299
10.9 China 302
10.9.1 Forecast 302
10.9.2 Key Events 305
10.9.3 Drivers and Barriers 305
10.10 India 308
10.10.1 Forecast 308
10.10.2 Key Events 312
10.10.3 Drivers and Barriers 312
11 Appendix 314
11.1 Bibliography 314
11.2 Abbreviations 344
11.3 Methodology 349
11.4 Forecasting Methodology 349
11.4.1 Number of NSCLC Patients Currently Seeking Treatment 349
11.4.2 Percent Drug-treated Patients 350
11.4.3 Drugs Included in Each Therapeutic Class 350
11.4.4 Launch and Patent Expiry Dates 351
11.4.5 General Pricing Assumptions 352
11.4.6 Individual Drug Assumptions 355
11.4.7 Generic Erosion 366
11.4.8 Pricing of Pipeline Agents 366
11.5 Physicians and Specialists Included in This Study 369
11.6 Survey of Prescribing Physicians 371
11.7 About the Authors 372
11.7.1 Author 372
11.7.2 Epidemiologist 372
11.7.3 Global Head of Healthcare 373
11.8 About GlobalData 374
11.9 Disclaimer 374
【レポート販売概要】
■ タイトル：非小細胞肺癌：世界市場（医薬品市場予測及び分析～2022）■ 英文：PharmaPoint: Non-Small Cell Lung Cancer - Global Drug Forecast and Market Analysis to 2022
■ 発行日：2013年6月30日
■ 調査会社：GlobalData
■ 商品コード：GDATA403161300
■ 調査対象地域：グローバル
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