【レポートの概要(一部)】
1 Table of Contents
1 Table of Contents 8
1.1 List of Tables 15
1.2 List of Figures 18
2 Introduction 20
2.1 Catalyst 20
2.2 Related Reports 20
2.3 Upcoming Related Reports 20
3 Disease Overview 21
3.1 Etiology and Pathophysiology 21
3.1.1 Etiology 21
3.1.2 Pathophysiology 23
3.2 Prognosis 27
3.3 Quality of Life 27
3.4 Symptoms 28
4 Epidemiology 30
4.1 Risk Factors and Comorbidities 30
4.1.1 Age and sex are highly associated with the risk of chronic heart failure 32
4.1.2 History of cardiovascular disease increases the risk of developing chronic heart failure 32
4.1.3 Unhealthy lifestyles increase the risk of chronic heart failure 33
4.1.4 People with diabetes mellitus are twice as likely to develop chronic heart failure 33
4.1.5 Nearly 20% of patients with chronic kidney disease develop chronic heart failure 34
4.1.6 Comorbidities 34
4.1.7 Prognosis for chronic heart failure remains poor 35
4.2 Global Trends 36
4.2.1 United States 36
4.2.2 France 37
4.2.3 Germany 38
4.2.4 Italy 38
4.2.5 Spain 38
4.2.6 United Kingdom 39
4.2.7 Japan 39
4.2.8 China 40
4.3 Forecast Methodology 40
4.3.1 Sources Used 40
4.3.2 Forecast Assumptions and Methods 45
4.3.3 Forecast Assumptions and Methods for New York Heart Association Class Distributions 48
4.3.4 Sources Not Used 49
4.4 Epidemiology Forecast (2012-2022) 49
4.4.1 Prevalent Cases of Chronic Heart Failure 49
4.4.2 Age-Specific Prevalent Cases 52
4.4.3 Sex-Specific Prevalent Cases 54
4.4.4 Age-Standardized Prevalence 59
4.4.5 New York Heart Association Class Distributions 61
4.5 Discussion 62
4.5.1 Limitations of Analysis 64
4.5.2 Strengths of Analysis 64
5 Disease Management 65
5.1 Treatment Overview 66
5.1.1 Pharmacological Treatments 68
5.1.2 Mechanical Devices 74
5.2 US 75
5.2.1 Diagnosis and Referral Patterns 75
5.2.2 Clinical Practice 76
5.3 France 77
5.3.1 Diagnosis and Referral Patterns 77
5.3.2 Clinical Practice 78
5.4 Germany 80
5.4.1 Diagnosis and Referral Patterns 80
5.4.2 Clinical Practice 80
5.5 Italy 82
5.5.1 Diagnosis and Referral Patterns 82
5.5.2 Clinical Practice 82
5.6 Spain 84
5.6.1 Diagnosis and Referral Patterns 84
5.6.2 Clinical Practice 85
5.7 UK 87
5.7.1 Diagnosis and Referral Patterns 87
5.7.2 Clinical Practice 88
5.8 Japan 90
5.8.1 Diagnosis and Referral Patterns 90
5.8.2 Clinical Practice 90
6 Competitive Assessment 92
6.1 Overview 92
6.2 Strategic Competitor Assessment 92
6.3 Drug Profiles 95
6.3.1 Angiotensin-Converting Enzyme (ACE) Inhibitors 95
6.3.2 Diuretics 98
6.3.3 Angiotensin Receptor Blockers 100
6.3.4 Beta Blockers 113
6.3.5 Procoralan (ivabradine) 125
6.3.6 Mineralocorticoid Receptor Antagonists 129
6.3.7 Digoxin 132
7 Opportunity and Unmet Need 135
7.1 Overview 135
7.2 Lack of Therapies for HF-PEF Patients 136
7.3 Lack of Therapies for Patients with Renal Impairment 137
7.4 Diagnosis of Asymptomatic Left Ventricular Dysfunction 137
7.5 Treatment of Patients with Multiple Comorbidities 138
7.6 Increase in Survival of CHF Patients 138
7.7 Unmet Needs Gap Analysis 139
7.8 Opportunity: Treatment of Patients with HF-PEF 140
7.9 Opportunity: Therapies for Patients with Renal Impairment and Multiple Comorbidities 140
7.10 Opportunity: New Drugs that Show Increase in Survival of CHF Patients 140
8 Pipeline Assessment 141
8.1 Overview 141
8.1.1 Clinical Trials by Country 142
8.2 Clinical Trials by Phase and Trial Status 143
8.3 Promising Drugs in Clinical Development 144
8.3.1 LCZ-696 145
8.3.2 Tekturna (aliskiren) 151
8.3.3 Neucardin (rhNRG-1) 155
8.4 Innovative Early-Stage Approaches 159
8.4.1 BAY 94-8862 159
8.4.2 Omecamtiv mecarbil 162
8.5 Promising Non-Pharmacological Approaches 165
8.5.1 MyoCell 166
8.5.2 C-Cure (C3BS-CQR-1) 171
8.5.3 Mydicar (rAAV1-SERCA2a) 174
9 Current and Future Players 179
9.1 Overview 179
9.2 Trends in Corporate Strategy 180
9.3 Company Profiles 181
9.3.1 Novartis 181
10 Market Outlook 185
10.1 Global Markets 185
10.1.1 Forecast 185
10.1.2 Drivers and Barriers – Global Issues 188
10.2 United States 191
10.2.1 Forecast 191
10.2.2 Key Events 195
10.2.3 Drivers and Barriers 195
10.3 France 197
10.3.1 Forecast 197
10.3.2 Key Events 200
10.3.3 Drivers and Barriers 200
10.4 Germany 201
10.4.1 Forecast 201
10.4.2 Key Events 204
10.4.3 Drivers and Barriers 204
10.5 Italy 205
10.5.1 Forecast 205
10.5.2 Key Events 207
10.5.3 Drivers and Barriers 208
10.6 Spain 209
10.6.1 Forecast 209
10.6.2 Key Events 211
10.6.3 Drivers and Barriers 212
10.7 United Kingdom 213
10.7.1 Forecast 213
10.7.2 Key Events 216
10.7.3 Drivers and Barriers 216
10.8 Japan 217
10.8.1 Forecast 217
10.8.2 Key Events 220
10.8.3 Drivers and Barriers 220
11 Appendix 223
11.1 Bibliography 223
11.2 Abbreviations 240
11.3 Methodology 244
11.4 Forecasting Methodology 244
11.4.1 NYHA Class Segmentation of Total Prevalent CHF Population 244
11.4.2 Diagnosed CHF Population 245
11.4.3 Drug-Treated CHF Population 246
11.4.4 Patient Population Breakdown: HF-REF versus HF-PEF 246
11.4.5 Treatment of HF-REF versus HF-PEF 246
11.4.6 Drugs Included in Each Therapeutic Class 247
11.4.7 Launch and Patent Expiry Dates 247
11.4.8 General Pricing Assumptions 248
11.4.9 Drugs Assumptions 249
11.4.10 Generic Erosion 254
11.4.11 Pricing of Pipeline Agents 254
11.5 Physicians and Specialists Included in this Study 255
11.6 Survey of Prescribing Physicians 256
11.7 About the Authors 257
11.7.1 Author 257
11.7.2 Epidemiologist 257
11.7.3 Global Head of Healthcare 258
11.8 About GlobalData 259
【レポート販売概要】
■ タイトル:慢性心不全:世界市場(医薬品市場予測及び分析~2022)■ 英文:PharmaPoint: Chronic Heart Failure - Global Drug Forecast and Market Analysis to 2022
■ 発行日:2013年6月30日
■ 調査会社:GlobalData
■ 商品コード:GDATA403161290
■ 調査対象地域:グローバル
- モバイルARの世界市場2017-2021About Augmented RealityAR technology is used to blend digital content into the physical world. Computer-generated images of an individual's surroundings along with relevant information are displayed in a user’s field of vision. The technology enhances user experience through mobiles apps developed specifically for using AR. The concept of AR has existed for several decades, although it has just ga …
- グリッドスケール電力貯蔵バッテリー(GSB)の世界市場Visiongain’s comprehensive new 227 page report reveals that CAPEX invested in grid scale battery (GSB) storage technologies will reach $717.2m in 2015, with rapid growth anticipated over the next ten years. Market scope: The grid scale battery (GSB) storage market is largely an emerging one, especially when compared with other energy storage systems such as the well-established pumped hydro storag …
- カウンタートップ式グリドルの世界市場ABSTRACTAbout Counter Top Griddle A countertop griddle is a cooking device used in various foodservice establishments and consists of a broad flat surface that is heated by gas or electricity. The majority of commercial grade countertop griddles are made from A36 steel. Some of the countertop griddles are also made of stainless steel or composites of aluminum and stainless steel. Technavio’s analy …
- 世界の家電向けモーションセンサー市場動向(2012-2016)TechNavio's analysts forecast the Global Consumer Motion Sensor market to grow at a CAGR of 15 percent over the period 2012-2016. One of the key factors contributing to this market growth is the increasing demand for smartphones and tablets. The Global Consumer Motion Sensor market has also been witnessing the emergence of motion sensor applications for interactive TV. However; the fluctuating glo …
- 太陽熱温水器の世界市場2017-2021About Solar Water Heater A solar water heater comprises solar collectors and storage tanks. It uses sunlight to heat water and is generally installed on the roof of a building. Two types of solar water heaters are available in the market: active and passive. While the active type uses pumps to circulate water, the passive type does not require any pumps or control units to circulate water. Unlike …
- 産業用冷凍の世界市場:提供品別(産業用冷却装置&構成要素)、構成要素別(コンプレッサー、コンデンサー、エバポレーター、コントロール、その他)、冷媒種類別(アンモニア、二酸化炭素、ハイドロフルオロカーボン(HFC)、その他)、用途別(フレッシュフルーツ&野菜、肉、家禽、魚、乳製品、アイスクリーム、飲料、化学薬品、医薬品、その他)、種類別(定置式冷凍&輸送用冷凍)The global industrial refrigeration market is expected to reach $29,133 million in 2026, from $19,666 million in 2018, growing at a CAGR of 4.9% from 2019 to 2026. Industrial refrigeration refers to the process of cooling using refrigeration and cooling systems to remove the heat from a low-temperature medium and transferring it to a high-temperature medium. Industrial refrigeration systems are de …
- 垂直農法の世界市場予測(~2022):栽培方法別(水耕栽培、空中栽培、アクアポニックス)、構造別、提供方法別、作物種類別、地域別According to the new market research report, the vertical farming market is expected to be valued at USD 5.80 Billion by 2022, growing at a CAGR of 24.8% between 2016 and 2022. The growth of the vertical farming market could be attributed to the growing urbanization, rising demand for high quality food with no use of pesticides and herbicides, and independent farming technique with low impact of c …
- LBS及びRTLSの世界市場The global Location Based Services market is expected to grow from USD 11.36 billion in 2015 to USD 54.95 billion by 2020, at a CAGR of 37.1%. Several factors such as increasing availability of spatial data and analytical tools, growing focus on business intelligence (BI), increasing market competitiveness, and decreasing cost of solutions are expected to bolster the growth of this market. The eme …
- ラプチャーディスク(破裂板)の世界市場2016-2020About Rupture Disc A rupture disc is a non-reclosing pressure relief device that is used to protect a pressure vessel or process system from over pressurization. It is used in production process systems across the oil and gas, chemical, power, pharmaceutical, food and beverage, pulp and paper, and aviation industries. A rupture disc controls and expels the excess pressure generated by the flow of …
- 随伴水処理サービスの世界市場This report estimates the produced water treatment services market in terms of value in $million. This has been broken down into component regions and further split into countries. The oil and gas industry produces large volumes of water every year alongside petroleum. Treatment of produced water is one of the major factors for facilitating the development in environmentally sensitive areas, and c …
- はしか(Measles):治療薬開発パイプライン動向(2015年上半期版)Measles - Pipeline Review, H1 2015 Summary Global Markets Direct’s, ‘Measles - Pipeline Review, H1 2015’, provides an overview of the Measles’s therapeutic pipeline. This report provides comprehensive information on the therapeutic development for Measles, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administratio …
- グリコールの世界市場分析:用途別(自動車、HVAC、テキスタイル、航空、医療、パイプライン補修繊維・樹脂、食品加工)、地域別、セグメント予測、2014-2025The global glycols market value is anticipated to exceed USD 47.2 billion by 2025, according to a new report by Grand View Research, Inc. The rising HVAC demand for advanced and high quality heating and cooling systems is expected to be a key factor steering the growth in the coming years. Glycols include ethylene, propylene and its derivatives are predominately used in the automotive sector as en …
- 獣医向け注入ポンプの米国市場予測(~2021):種類別(大容量注入ポンプ、シリンジ注入ポンプ)、需要先別The top 10 sensors market is expected to grow at a significant rate during the forecast period. The growth of this market is propelled by the increasing advancement toward smaller, smarter, and cheaper sensors; miniaturization trend in sensors; advent of platforms such as IoT, AR, and M2M; and growing trend toward smart living among end users. This report categorizes the top 10 sensors market on t …
- 自己輸血デバイスの世界市場予測・分析2020-2024Global Autotransfusion Devices Market: About this market Technavio’s autotransfusion devices market analysis considers sales from both systems and accessories products. Our study also finds the sales of autotransfusion devices in Asia, Europe, North America, and ROW. In 2019, the systems segment had a significant market share, and this trend is expected to continue over the forecast period. Factor …
- 内視鏡検査システムの世界市場:予測とディスカッション2016-2026Endoscopy for Medicine: Why You Cannot Afford to Overlook that Rising Market – Introducing Your Guide to its Sales Potential What is the future of endoscopic devices and their producers? Visiongain’s new report gives you that data and analysis, helping you explore developments, technology and revenue predictions for endoscopic applications in healthcare. Discover where that industry heads. Our inv …