【レポートの概要（一部）】
Table of Contents
Table of Contents 2
List of Tables 4
List of Figures 4
Introduction 5
Global Markets Direct Report Coverage 5
Paroxysmal Nocturnal Hemoglobinuria Overview 6
Therapeutics Development 7
Pipeline Products for Paroxysmal Nocturnal Hemoglobinuria – Overview 7
Pipeline Products for Paroxysmal Nocturnal Hemoglobinuria – Comparative Analysis 8
Paroxysmal Nocturnal Hemoglobinuria – Therapeutics under Development by Companies 9
Paroxysmal Nocturnal Hemoglobinuria – Pipeline Products Glance 10
Clinical Stage Products 10
Early Stage Products 11
Paroxysmal Nocturnal Hemoglobinuria – Products under Development by Companies 12
Paroxysmal Nocturnal Hemoglobinuria – Companies Involved in Therapeutics Development 13
Achillion Pharmaceuticals, Inc. 13
Alnylam Pharmaceuticals, Inc. 14
Amyndas Pharmaceuticals LLC 15
Apellis Pharmaceuticals, Inc. 16
Omeros Corporation 17
Ra Pharmaceuticals, Inc. 18
Shire Plc 19
Paroxysmal Nocturnal Hemoglobinuria – Therapeutics Assessment 20
Assessment by Monotherapy Products 20
Assessment by Target 21
Assessment by Mechanism of Action 23
Assessment by Route of Administration 25
Assessment by Molecule Type 27
Drug Profiles 29
ACH-CFDIS – Drug Profile 29
Product Description 29
Mechanism of Action 29
R&D Progress 29
ALN-CC5 – Drug Profile 30
Product Description 30
Mechanism of Action 30
R&D Progress 30
AMY-101 – Drug Profile 31
Product Description 31
Mechanism of Action 31
R&D Progress 31
APL-2 – Drug Profile 32
Product Description 32
Mechanism of Action 32
R&D Progress 32
C1 esterase inhibitor (human) – Drug Profile 34
Product Description 34
Mechanism of Action 34
R&D Progress 34
Coversin – Drug Profile 36
Product Description 36
Mechanism of Action 36
R&D Progress 36
Monoclonal Antibody for Paroxysmal Nocturnal Hemoglobinuria – Drug Profile 37
Product Description 37
Mechanism of Action 37
R&D Progress 37
NM-9405 – Drug Profile 38
Product Description 38
Mechanism of Action 38
R&D Progress 38
OMS-721 – Drug Profile 39
Product Description 39
Mechanism of Action 39
R&D Progress 39
RA-101348 – Drug Profile 41
Product Description 41
Mechanism of Action 41
R&D Progress 41
Paroxysmal Nocturnal Hemoglobinuria – Recent Pipeline Updates 42
Paroxysmal Nocturnal Hemoglobinuria – Dormant Projects 51
Paroxysmal Nocturnal Hemoglobinuria – Product Development Milestones 52
Featured News & Press Releases 52
Dec 04, 2014: Ra Pharmaceuticals Announces Presentation of Data Supporting Clinical Development of Novel Complement C5 Inhibitor at 2014 ASH Annual Meeting 52
Mar 28, 2013: Omeros Announces Toxicology Data That Support Advancing MASP-2 Inhibitor Into Clinical Trials 53
Feb 07, 2013: Omeros Announces Toxicology Study Data From MASP-2 Inhibitor 54
Appendix 56
Methodology 56
Coverage 56
Secondary Research 56
Primary Research 56
Expert Panel Validation 56
Contact Us 56
Disclaimer 57
【レポート販売概要】
■ タイトル：発作性夜間ヘモグロビン尿症(Paroxysmal Nocturnal Hemoglobinuria)：治療薬開発パイプライン動向（2015年上半期版）■ 英文：Paroxysmal Nocturnal Hemoglobinuria - Pipeline Review, H1 2015
■ 発行日：2015年3月19日
■ 調査会社：Global Markets Direct
■ 商品コード：GMDHC6427IDB
■ 調査対象地域：グローバル
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