主要先進国における乳癌治療市場（～2020）...市場調査レポートについてご紹介

1 Table of Contents
1 Table of Contents 5
1.1 List of Tables 7
1.2 List of Figures 8
2 Breast Cancer Therapeutics in Major Developed Markets to 2020 – Introduction 9
2.1 Breast Cancer 9
2.2 Symptoms 9
2.3 Epidemiology 10
2.4 Pathophysiology 11
2.5 Diagnosis 11
2.6 Prognosis and Disease Staging 12
2.6.1 Classification 13
2.7 Treatment Options 14
2.7.1 Surgery and Radiation Therapy 14
2.7.2 Chemotherapy 14
2.7.3 Hormonal Therapies 15
2.7.4 Targeted Therapies 15
2.7.5 Resistance to Pharmacological Therapies 16
2.7.6 Treatment Guidelines 17
2.7.7 Measuring the Effectiveness of Treatment 18
3 Breast Cancer Therapeutics in Major Developed Markets to 2020 – Marketed Products 20
3.1 Key Marketed Products 20
3.1.1 Herceptin 20
3.1.2 Halaven 21
3.1.3 Avastin 22
3.1.4 Gemzar 23
3.1.5 Taxotere 23
3.1.6 Tykerb 24
3.1.7 Femara 25
3.1.8 Aromasin 26
3.1.9 Zoladex 26
3.1.10 Arimidex 27
3.2 Heat Map for Marketed Products 27
4 Breast Cancer Therapeutics in Major Developed Markets to 2020 – Pipeline Analysis 29
4.1 Overall Pipeline 29
4.2 Pipeline Analysis by Molecule Type 31
4.3 Pipeline Analysis by Mechanism of Action 33
4.4 Clinical Trials – Failure Rate 35
4.5 Clinical Trial Size 37
4.6 Duration 39
4.7 Promising Drug Candidates in Pipeline 40
4.7.1 Buparlisib 40
4.7.2 Palbociclib 40
4.7.3 Afatinib dimaleate 40
4.7.4 Entinostat 41
4.7.5 Neratinib 42
4.7.6 BMN-673 42
4.7.7 Etirinotecan pegol 42
4.7.8 MetmAb (onartuzumab) 43
5 Breast Cancer Therapeutics in Major Developed Markets to 2020 – Market Forecast to 2020 44
5.1 Global Market 44
5.1.1 Treatment Use Patterns 44
5.1.2 Market Size 44
5.2 North America 46
5.2.1 Treatment Use Patterns 46
5.2.2 Annual Cost of Therapy 47
5.2.3 Market Size 49
5.3 Top Five European Markets 51
5.3.1 Treatment Use Patterns 51
5.3.2 Annual Cost of Therapy 52
5.3.3 Market Size 53
5.4 Japan 54
5.4.1 Treatment Use Patterns 54
5.4.2 Annual Cost of Therapy 54
5.4.3 Market Size 54
5.5 Drivers and Barriers for the Breast Cancer Therapeutics in Asia-Pacific Market to 2020 56
5.5.1 Drivers 56
5.5.2 Barriers 56
6 Breast Cancer Therapeutics in Major Developed Markets to 2020 – Deals and Strategic Consolidations 58
6.1 Licensing Agreements 58
6.1.1 Major Licensing Deals 61
6.2 Co-development Agreements 62
6.2.1 Major Co-development Agreements 64
7 Breast Cancer Therapeutics in Major Developed Markets to 2020 – Appendix 66
7.1 All Pipeline Drugs by Phase 66
7.1.1 Discovery 66
7.1.2 Preclinical 69
7.1.3 IND/CTA-Filed and Phase I 79
7.1.4 Phase II 85
7.1.5 Phase III 91
7.1.6 Pre-Registration 93
7.2 Market Forecasts to 2020 94
7.2.1 Global 94
7.2.2 US 94
7.2.3 Canada 95
7.2.4 UK 95
7.2.5 France 95
7.2.6 Germany 96
7.2.7 Italy 96
7.2.8 Spain 96
7.2.9 Japan 97
7.3 Market Definitions 97
7.4 Abbreviations 97
7.5 References 99
7.6 Research Methodology 102
7.6.1 Coverage 102
7.6.2 Secondary Research 102
7.6.3 Primary Research 103
7.6.4 Therapeutic Landscape 103
7.6.5 Geographical Landscape 105
7.6.6 Pipeline Analysis 106
7.7 Expert Panel Validation 106
7.8 Contact Us 106
7.9 Disclaimer 106