【英文タイトル】Kappaproct (Ulcerative Colitis) - Forecast and Market Analysis to 2022



1 Table of Contents
1 Table of Contents 5
1.1 List of Tables 7
1.2 List of Figures 8
2 Introduction 9
2.1 Catalyst 9
2.2 Related Reports 9
2.3 Upcoming Related Reports 11
3 Disease Overview 12
3.1 Etiology and Pathophysiology 12
3.1.1 Etiology 12
3.1.2 Pathophysiology 14
3.2 Symptoms 16
3.2.1 Quality of Life 16
4 Disease Management 18
4.1 Diagnosis and Treatment Overview 18
4.1.1 Diagnosis 18
4.1.2 Treatment Guidelines and Leading Prescribed Drugs 21
4.1.3 Clinical Practice 23
5 Competitive Assessment 27
5.1 Overview 27
5.2 Strategic Competitor Assessment 28
6 Opportunity and Unmet Need 30
6.1 Overview 30
6.2 Unmet Needs 31
6.2.1 Curative Therapy for Severe UC Patients 31
6.2.2 Diagnostic Markers for Disease Severity 31
6.2.3 Personalized Therapy 32
6.2.4 A Replacement for Steroids 32
6.2.5 Novel Oral Drug Formulations 33
6.2.6 Preventative Medicine for Lowering the Associated Colorectal Cancer Risk 34
6.2.7 Improved Management of Infectious Adverse Events 34
6.3 Unmet Needs Gap Analysis 35
6.4 Disease Severity and Colorectal Cancer Biomarker-Based Prognostic Tools 36
6.5 Predictors of Medically-Refractory Disease 37
7 Pipeline Assessment 38
7.1 Overview 38
7.2 Promising Drugs in Clinical Development 38
8 Kappaproct (DIMS 0150) 40
8.1 Overview 40
8.2 Efficacy 41
8.3 Safety 42
8.4 Dosing and Formulation 42
8.5 Potential Clinical Positioning 42
8.6 Potential Commercial Positioning 43
8.7 Pricing and Reimbursement 43
8.8 SWOT Analysis 44
8.9 Forecast 44
9 Appendix 46
9.1 Bibliography 46
9.2 Abbreviations 48
9.3 Methodology 52
9.4 Forecasting Methodology 52
9.4.1 Diagnosed UC Patients 52
9.4.2 Percent Drug-Treated Patients 53
9.4.3 General Pricing Assumptions 53
9.4.4 Generic Erosion 54
9.4.5 Pricing of Pipeline Agents 54
9.5 Physicians and Specialists Included in This Study 55
9.6 Primary Research – Prescriber Survey 56
9.7 About the Authors 57
9.7.1 Author 57
9.8 About GlobalData 58
9.9 Disclaimer 58


■ タイトル:Kappaproct(潰瘍性大腸炎):市場分析と予測(~2022)
■ 英文:Kappaproct (Ulcerative Colitis) - Forecast and Market Analysis to 2022
■ 発行日:2014年2月28日
■ 調査会社:GlobalData
■ 商品コード:GDHC344DFR
■ 調査対象地域:グローバル
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