Safinamide (パーキンソン病):医薬品市場予測及び分析(~2022)...市場調査レポートについてご紹介

【英文タイトル】Safinamide (Parkinson’s Disease) - Forecast and Market Analysis to 2022



1 Table of Contents
1 Table of Contents 5
1.1 List of Tables 8
1.2 List of Figures 9
2 Introduction 10
2.1 Catalyst 10
2.2 Related Reports 10
3 Disease Overview 13
3.1 Etiology and Pathophysiology 13
3.1.1 Etiology 13
3.1.2 Pathophysiology 16
3.1.3 Prognosis 18
3.1.4 Quality of Life 19
3.2 Symptoms 19
4 Disease Management 21
4.1 Overview 21
4.1.1 Diagnosis – The UK Brain Bank Criteria 21
4.1.2 Treatment Guidelines and Leading Prescribed Drugs 22
4.2 Treatment Synopsis 25
4.2.1 Dopaminergic Therapy Classes 25
4.2.2 Treatment of Parkinson’s Disease by Stage 27
4.2.3 Other Treatment Options 30
4.3 Parkinson’s Disease Assessment Scales 30
4.3.1 Unified Parkinson’s Disease Rating Scale (UPDRS) 31
4.3.2 Hoehn and Yahr Clinical Staging 33
4.3.3 Other Clinical Assessments 34
5 Competitive Assessment 35
5.1 Overview 35
5.2 Strategic Competitor Assessment 37
6 Opportunity and Unmet Need 38
6.1 Overview 38
6.2 Treatment of Motor Complications – Dyskinesias and OFF Episodes 40
6.2.1 Unmet Need 40
6.2.2 Gap Analysis 42
6.2.3 Opportunity 45
6.3 Treatment of Non-Motor Symptoms and Dementia 45
6.3.1 Unmet Need 45
6.3.2 Gap Analysis 46
6.3.3 Opportunity 48
6.4 Neuroprotective/Disease-Modifying Agents 48
6.4.1 Unmet Need 48
6.4.2 Gap Analysis 49
6.4.3 Opportunity 52
6.5 Improved Drug Formulations 53
6.5.1 Unmet Need 53
6.5.2 Gap Analysis 53
6.5.3 Opportunity 54
6.6 Identification of Reliable Biomarkers 54
6.6.1 Unmet Need 54
6.6.2 Gap Analysis 55
6.6.3 Opportunity 56
6.7 Improved Clinical Trial Design 56
6.7.1 Unmet Need 56
6.7.2 Gap Analysis 57
6.7.3 Opportunity 57
7 Pipeline Assessment 58
7.1 Overview 58
7.2 Promising Drugs in Clinical Development 58
8 Safinamide 61
8.1 Overview 61
8.2 Efficacy 62
8.3 Safety 64
8.4 Dosing and Formulation 64
8.5 Potential Clinical Positioning 64
8.6 Potential Commercial Positioning 65
8.7 Pricing and Reimbursement 65
8.8 SWOT Analysis 66
8.9 Forecast 66
9 Appendix 68
9.1 Bibliography 68
9.2 Abbreviations 74
9.3 Methodology 78
9.4 Forecasting Methodology 78
9.4.1 Diagnosed Parkinson’s Disease Patients 78
9.4.2 Percent Drug-Treated Patients 79
9.4.3 General Pricing Assumptions 79
9.4.4 Compliance Assumptions 80
9.4.5 Individual Drug Assumptions 80
9.4.6 Generic Erosion 81
9.4.7 Pricing of Pipeline Agent 81
9.5 Physicians and Specialists Included in this Study 82
9.6 About the Authors 84
9.6.1 Author 84
9.6.2 Global Head of Healthcare 85
9.7 About GlobalData 86
9.8 Disclaimer 86


■ タイトル:Safinamide (パーキンソン病):医薬品市場予測及び分析(~2022)
■ 英文:Safinamide (Parkinson’s Disease) - Forecast and Market Analysis to 2022
■ 発行日:2014年3月31日
■ 調査会社:GlobalData
■ 商品コード:GDHC398DFR
■ 調査対象地域:グローバル
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