【レポートの概要（一部）】
1 Table of Contents
1 Table of Contents 11
1.1 List of Tables 17
1.2 List of Figures 24
2 Introduction 26
2.1 Catalyst 26
2.2 Related Reports 28
2.3 Upcoming Related Reports 28
3 Disease Overview 29
3.1 Etiology and Pathophysiology 29
3.1.1 Etiology 29
3.1.2 Pathophysiology 31
3.2 Symptoms 35
3.3 Prognosis 35
3.4 Quality of Life 35
4 Epidemiology 36
4.1 Risk Factors and Comorbidities 36
4.2 Global and Historical Trends 37
4.2.1 US 38
4.2.2 5EU 38
4.2.3 Asia 40
4.3 Forecast Methodology 41
4.3.1 Sources Used 49
4.3.2 Forecast Assumptions and Methods 55
4.3.3 Sources Not Used 81
4.4 Prevalent Cases of Dyslipidemia 82
4.4.1 Total Prevalent Cases of Dyslipidemia 82
4.4.2 Age-Specific Total Prevalent Cases of Dyslipidemia 83
4.4.3 Sex-Specific Total Prevalent Cases of Dyslipidemia 85
4.4.4 Age-Standardized Total Prevalence of Dyslipidemia 87
4.5 Epidemiological Forecast for Familial Hypercholesterolemia (2013-2023) 88
4.5.1 Total Prevalent Cases of Familial Hypercholesterolemia 88
4.6 Epidemiological Forecast for Increased LDL-C (2013-2023) 89
4.6.1 Total Prevalent Cases of Increased LDL-C 89
4.6.2 Age-Specific Total Prevalent Cases of Increased LDL-C 91
4.6.3 Sex-Specific Total Prevalent Cases of Increased LDL-C 93
4.6.4 Age-Standardized Total Prevalence of Increased LDL-C 95
4.7 Epidemiological Forecast for Very High TG (≥500mg/dL) (2013-2023) 96
4.7.1 Total Prevalent Cases of Very High TG (≥500mg/dL) 96
4.7.2 Age-Specific Total Prevalent Cases of Very High TG (≥500mg/dL) 98
4.7.3 Sex-Specific Total Prevalent Cases of Very High TG (≥500mg/dL) 100
4.7.4 Age-Standardized Total Prevalence of Very High TG (≥500mg/dL) 102
4.8 Discussion 103
4.8.1 Epidemiological Forecast Insight 103
4.8.2 Limitations of the Analysis 104
4.8.3 Strengths of the Analysis 105
5 Disease Management 106
5.1 Diagnosis and Treatment Overview 106
5.1.1 Diagnosis 106
5.1.2 Treatment Guidelines and Leading Prescribed Drugs 108
5.1.3 Clinical Practice 111
5.2 US 113
5.3 France 117
5.4 Germany 119
5.5 Italy 122
5.6 Spain 125
5.7 UK 126
5.8 Japan 129
5.9 China 131
6 Competitive Assessment 134
6.1 Overview 134
6.2 Product Profiles – Major Brands 138
6.2.1 Statins 138
6.2.2 Zetia (ezetimibe) 158
6.2.3 Vytorin (simvastatin/ezetimibe) 167
6.2.4 Liptruzet (atorvastatin/ezetimibe) 171
6.2.5 Niaspan (niacin extended-release) 175
6.2.6 Kynamro (mipomersen sodium) 181
6.2.7 Juxtapid (lomitapide) 188
6.2.8 TriCor/Trilipix (fenofibrate/fenfibric acid) 193
6.2.9 Omega-3 Fatty Acids 198
6.2.10 Welchol (colesevelam HCl) and the Bile Acid Sequestrants 213
7 Unmet Need and Opportunity 219
7.1 Overview 219
7.2 LDL-C-Lowering Drugs for Statin-Intolerant and Statin-Refractory Patients 220
7.2.1 Unmet Need 220
7.2.2 Gap Analysis 221
7.2.3 Opportunity 222
7.3 Improved Diagnosis, Patient Education, and Long-term Compliance 223
7.3.1 Unmet Need 223
7.3.2 Gap Analysis 224
7.3.3 Opportunity 226
7.4 Therapies that Prevent or Reverse the Build-Up of Atherosclerotic Plaque 227
7.4.1 Unmet Need 227
7.4.2 Gap Analysis 228
7.4.3 Opportunity 229
7.5 Therapies for Patients with HoFH with Improved Side Effect Profiles 230
7.5.1 Unmet Need 230
7.5.2 Gap Analysis 231
7.5.3 Opportunity 232
8 Pipeline Assessment 233
8.1 Overview 233
8.2 Clinical Trial Mapping 237
8.2.1 Clinical Trials by Patient Population 237
8.3 Promising Drugs in Clinical Development 237
8.3.1 Alirocumab 237
8.3.2 Bococizumab 246
8.3.3 Evolocumab 251
8.3.4 Anacetrapib 260
8.3.5 Evacetrapib 268
8.3.6 TA-8995 (DEZ-001) 274
8.3.7 CER-001 280
8.3.8 ETC-1002 286
8.4 Other Drugs in Development 294
9 Current and Future Players 295
9.1 Overview 295
9.2 Trends in Corporate Strategy 300
9.3 Company Profiles 302
9.3.1 AbbVie 302
9.3.2 Aegerion Pharmaceuticals, Inc. 304
9.3.3 Amarin 306
9.3.4 Amgen 308
9.3.5 AstraZeneca 310
9.3.6 Cerenis Therapeutics Inc. 313
9.3.7 Daiichi Sankyo 315
9.3.8 Dezima Pharma 317
9.3.9 Eli Lilly 319
9.3.10 Esperion Therapeutics, Inc. 322
9.3.11 Genzyme 324
9.3.12 GlaxoSmithKline 326
9.3.13 Merck & Co. 328
9.3.14 Pfizer 331
9.3.15 Regeneron Pharmaceuticals, Inc. 333
9.3.16 Sanofi 335
10 Market Outlook 339
10.1 Global Markets 339
10.1.1 Forecast 339
10.1.2 Drivers and Barriers – Global Issues 348
10.2 United States 351
10.2.1 Forecast 351
10.2.2 Key Events 356
10.2.3 Drivers and Barriers 357
10.3 5EU 359
10.3.1 Forecast 359
10.3.2 Key Events 367
10.3.3 Drivers and Barriers 368
10.4 Japan 371
10.4.1 Forecast 371
10.4.2 Key Events 374
10.4.3 Drivers and Barriers 375
10.5 China 377
10.5.1 Forecast 377
10.5.2 Key Events 381
10.5.3 Drivers and Barriers 381
11 Appendix 384
11.1 Bibliography 384
11.2 Abbreviations 412
11.3 Methodology 420
11.4 Forecasting Methodology 420
11.4.1 Diagnosed Dyslipidemia Patients 420
11.4.2 Percent Drug-Treated Patients 421
11.4.3 Drugs Included in Each Therapeutic Class 421
11.4.4 Launch and Patent Expiry Dates 422
11.4.5 General Pricing Assumptions 423
11.4.6 Individual Drug Assumptions 424
11.4.7 Generic Erosion 431
11.4.8 Pricing of Pipeline Agents 431
11.5 Physicians and Specialists Included in this Study 432
11.6 About the Authors 434
11.6.1 Analyst 434
11.6.2 Therapy Area Director 435
11.6.3 Epidemiologist 435
11.6.4 Global Head of Healthcare 436
11.7 About GlobalData 437
11.8 Disclaimer 437
【レポート販売概要】
■ タイトル：脂質異常症治療薬の世界市場予測および分析■ 英文：PharmaPoint: Dyslipidemia - Global Drug Forecast and Market Analysis to 2023
■ 発行日：2015年5月5日
■ 調査会社：GlobalData
■ 商品コード：GDHC110PIDR
■ 調査対象地域：グローバル
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