【英文タイトル】Colorectal Cancer Therapeutics in Major Developed Markets to 2020 - Increased Uptake of High Priced Drugs to Offset the Impact of Generics



1 Table of Contents
1 Table of Contents 5
1.1 List of Tables 7
1.2 List of Figures 8
2 Introduction 9
2.1 Colorectal Cancer 9
2.2 Symptoms 9
2.3 Epidemiology 9
2.4 Pathophysiology 10
2.4.1 Histology 10
2.4.2 Genetic Basis 10
2.4.3 Etiology of Colorectal Cancer 10
2.5 Diagnosis 12
2.5.1 Digital Rectal Examination 12
2.5.2 Fecal Occult Blood Test 12
2.5.3 Flexible Sigmoidoscopy 12
2.5.4 Colonoscopy 13
2.5.5 Virtual Colonoscopy 13
2.5.6 Double Contrast Barium Enema 13
2.6 Prognosis and Disease Staging 14
2.7 Treatment Options 15
2.7.1 Surgery and Radiation Therapy 16
2.7.2 Chemotherapy 16
2.7.3 Targeted Therapies 16
2.7.4 Resistance to Pharmacological Therapies 17
2.7.5 Treatment Guidelines 18
3 Marketed Products 22
3.1 Key Marketed Products 22
3.1.1 Immunotherapies 22
3.1.2 Targeted Therapies 25
3.1.3 Hyperthermic Intraperitoneal Chemotherapy 30
3.2 Heat Map for Marketed Products 31
4 Pipeline Analysis 33
4.1 Overall Pipeline 33
4.2 Pipeline Analysis by Molecule Type 34
4.3 Pipeline Analysis by Mechanism of Action 35
4.4 Clinical Trials 37
4.5 Failure Rate 37
4.6 Clinical Trial Size 39
4.7 Duration 41
4.8 Promising Drug Candidates in Pipeline 43
4.8.1 Lonsurf (TAS-102 (tipiracil + trifluridine)) – Taiho Pharmaceutical 43
4.8.2 Cyramza – ramucirumab – Eli Lilly and Company 43
4.8.3 TS-1/Teysuno (tegafur + gimeracil + oteracil) – Taiho Pharmaceutical 44
4.8.4 CPP-1X (eflornithine hydrochloride) + sulindac – Cancer Prevention Pharmaceuticals 45
4.8.5 MelCancerVac – DanDrit Biotech 46
4.8.6 Xilonix – XBiotech 47
4.8.7 Nintedanib – Boehringer Ingelheim 47
5 Market Forecast to 2020 49
5.1 Global Market 49
5.1.1 Treatment Use Patterns 49
5.1.2 Market Size 49
5.2 North America 50
5.2.1 Treatment Use Patterns 50
5.2.2 Annual Cost of Therapy 51
5.2.3 Market Size 52
5.3 Top Five European Markets 53
5.3.1 Treatment Use Patterns 53
5.3.2 Annual Cost of Therapy 55
5.3.3 Market Size 56
5.4 Japan 57
5.4.1 Treatment Use Patterns 57
5.4.2 Annual Cost of Therapy 58
5.4.3 Market Size 59
5.5 Drivers and Barriers for the Colorectal Cancer Therapeutics in Major Developed Markets to 2020 60
5.5.1 Drivers 60
5.5.2 Barriers 61
6 Deals and Strategic Consolidations 63
6.1 Licensing Agreements 63
6.1.1 Major Licensing Deals 64
6.2 Co-development Agreements 65
6.2.1 Major Co-development Agreements 67
7 Appendix 68
7.1 All Pipeline Drugs by Phase 68
7.1.1 Discovery 68
7.1.2 Preclinical 70
7.1.3 IND/CTA-Filed 75
7.1.4 Phase I 75
7.1.5 Phase II 80
7.1.6 Phase III 86
7.2 Market Forecasts to 2020 87
7.2.1 Global 87
7.2.2 US 87
7.2.3 Canada 88
7.2.4 UK 88
7.2.5 France 88
7.2.6 Germany 89
7.2.7 Italy 89
7.2.8 Spain 89
7.2.9 Japan 90
7.3 Market Definitions 90
7.4 Abbreviations 91
7.5 References 94
7.6 References for Heat Map 99
7.7 Research Methodology 100
7.7.1 Coverage 100
7.7.2 Secondary Research 100
7.7.3 Primary Research 101
7.7.4 Therapeutic Landscape 101
7.7.5 Geographical Landscape 104
7.7.6 Pipeline Analysis 104
7.8 Expert Panel Validation 104
7.9 Contact Us 104
7.10 Disclaimer 104


■ タイトル:世界主要国における大腸癌治療薬市場
■ 英文:Colorectal Cancer Therapeutics in Major Developed Markets to 2020 - Increased Uptake of High Priced Drugs to Offset the Impact of Generics
■ 発行日:2015年1月31日
■ 調査会社:GBI Research
■ 商品コード:GBIHC352MR
■ 調査対象地域:グローバル
  • 半導体検査装置の世界市場:ウェハ検査装置、マスク検査装置
    About Inspection Systems Inspection systems are part of fabrication equipment in the semiconductor device manufacturing process. These systems are used to find defects in masks and wafers during the production process of semiconductor wafers. The growing application of semiconductor ICs in segments like automobiles, consumer electronics, and industrial sector has compelled semiconductor ICs vendor …
  • シャワーカーテン小売りの世界市場2019-2023
    About this market Increased demand for personalized and customized shower curtains to drive market growth. Personalization and customization of home textile products (such as shower curtains) are emerging trends, especially in developed countries such as the US, Germany, and France. This is one of the major factors propelling purchase decisions. Technavio’s analysts have predicted that the shower …
  • キックボクシング用品の世界市場2016-2020
    About Kickboxing Equipment Kickboxing is a type of combat sport that was derived from Muay Thai (also known as Thai Boxing), boxing, and karate. Kickboxing garnered notable popularity since its advent in the US during early 1970s. The first world championship full contact kickboxing was organized by the Professional Karate Association (PKA) in 1974. Since then, kickboxing has become a recognized s …
  • 屋内外用ビーンズバッグの世界市場2019-2023
    About this market The product portfolio extension leading to product premiumization is one of the critical reasons that will drive the indoor and outdoor bean bags market. Vendors are focusing on gaining a strong foothold in the market and increase their customer base by introducing a wide variety of bean bags in terms of colors and new designs. They are launching stylish furniture and furnishing …
  • ヨーロッパの小水力発電市場分析:Looking at Small Hydropower in Europe
    The role of water as a multi-faceted necessity for humans cannot be more stressed upon since as many adaptive uses that were demanded of it by civilizations; water has met most of them or in some cases - all. Nature’s most wonderful resource never ceases to amaze imaginations as it proves to be a resource with the capacity to generate power in many forms whether be it hydropower or steam power to …
  • Bluetoothスピーカーの世界市場
    About Bluetooth Speakers Bluetooth speakers are used to listen to music. They work on wireless technology that allows the user to send and receive files and data without wire. The Bluetooth speakers are portable, and are, therefore, easy to use and carry, and easy to install. Bluetooth speakers are of the following types: AC/DC Bluetooth speakers, AC-only Bluetooth speakers, and DC-only Bluetooth …
  • インドの乳製品市場動向(~2022)
    Indian Dairy Industry holds an inimitable space in the country for its high employment potential and for ensuring the availability of nutritious yet affordable food for India’s ever increasing population. Getting the tag of largest milk producer was made possible by Operation Flood and the historic dairy cooperative movement; and as production increased, dairy industry started showing promising gr …
  • 医療用レーザシステムの世界市場:ダイオードレーザ、固体レーザ、ガスレーザ、色素レーザ
    About Medical Laser System Medical laser system consists of a wide variety of monochromatic light with a specific wavelength that has strong emission and is highly concentrated. The demand for lasers used in the field of medicine is increasing at a rapid rate due to the versatility of its light. The characteristics of laser light are defined by its power, wavelength, and pulsed or continuous wave …
  • 女性用コンドームの世界市場2017-2021
    About Female Condoms A female condom is a birth control device that acts as a barrier to prevent sexual fluids from entering the vagina during intercourse. It protects against pregnancy and sexually transmitted infections (STIs). Technavio’s analysts forecast the global female condoms market to grow at a CAGR of 9.02% during the period 2017-2021. [Covered in this report] The report covers the pres …
  • CoxsackievirusTesting Market 2014
    The report presents a detailed analysis of the Coxsackievirus diagnostics market in the US, Europe, (France, Germany, Italy, Spain, UK) and Japan. Current scientific views on the Coxsackievirus definition, epidemiology and etiology are reviewed. The report provides the 5-year test volume and sales forecasts by country for the following market segments:     - Hospitals    & …
  • 太陽光発電ガラスの世界市場:種類別(反射防止コーティングガラス、強化ガラス、TCOガラス、その他)、最終用途産業別(住宅、商業、実用規模)
    Photovoltaic (PV) glass integrates solar cells to convert solar energy into electricity. The solar cells are fixed between two glass panes with a filling of special resin. These resins securely wrap solar cells from all sides. Each cell is connected with two electrical connections and is attached to other cells to form a module. Supportive government regulations toward installation of solar PV pla …
  • Hodgkin Lymphoma:グローバル臨床試験レビューH2, 2013
    Hodgkin Lymphoma Global Clinical Trials Review, H2, 2013 Summary GlobalData's clinical trial report, “Hodgkin Lymphoma Global Clinical Trials Review, H2, 2013" provides data on the Hodgkin Lymphoma clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Hodgkin Lymphoma . It includes an overview of the trial numbers and their recruitment stat …
  • プロピレングリコール(PG)の世界市場動向及び予測2015
    The present report is an essential resource for a one looking for detailed information on the world propylene glycol market. The report covers data on global, regional and national markets including present and future trends for supply and demand, prices, and downstream industries. In addition to the analytical part, the report provides a range of tables and figures which all together give a true …
  • 化学療法誘発性疼痛:グローバル臨床試験レビュー(2014年上半期)
    Chemotherapy Induced Pain Global Clinical Trials Review, H1, 2014 Summary GlobalData's clinical trial report, “Chemotherapy Induced Pain Global Clinical Trials Review, H1, 2014" provides data on the Chemotherapy Induced Pain clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Chemotherapy Induced Pain. It includes an overview of the trial …
  • 自動車用ベアリングの世界市場:玉軸受、ころ軸受
    The report covers the bearing market in terms of volume & value. The market size in terms of volume is provided from 2013 to 2020 in units, whereas the value of the market is provided in $million. The construction and mining equipment market is broadly classified by geography (Asia-Pacific, Europe, North America, and RoW), by vehicle type (PC, LCV, HCV & Two-Wheelers), by bearing type (Roller bear …