乳癌治療のグローバル市場:画期的新薬の発見と商用化...市場調査レポートについてご紹介

【英文タイトル】Frontier Pharma: Breast Cancer - Identifying and Commercializing First-in-Class Innovation

▼当市場調査レポートの詳細内容確認、お問い合わせ及びご購入申込は下記ページでお願いします。▼マーケットレポート

【レポートの概要(一部)】

1 Table of Contents
1 Table of Contents 2
1.1 List of Tables 3
1.2 List of Figures 3

2 Executive Summary 4
2.1 Exceptionally Large and Innovative Pipeline 4
2.2 Alignment of First-in-Class Molecular Target with Disease Causation 4
2.3 A Highly Active Deals Landscape with Numerous Investment Opportunities 4

3 The Case for Innovation in the Breast Cancer Market 5
3.1 Growing Opportunities for Biologic Products 5
3.2 Diversification of Molecular Targets 5
3.3 Innovative First-in-Class Product Developments Remain Attractive 5
3.4 Changes in the Clinical and Commercial Environment to be More Favorable to Products Targeting Niche Patient Populations and Indications 6
3.5 Sustained Innovation 6
3.6 Report Guidance 6

4 Clinical and Commercial Landscape 8
4.1 Disease Overview 8
4.2 Disease Symptoms 8
4.3 Etiology 8
4.4 Pathophysiology 9
4.4.1 Tumor Initiation, and Aberrant Cell Proliferation and Survival 10
4.4.2 Tumor Metabolic Shift 11
4.4.3 Tumor Progression, Microenvironment Alteration and Angiogenesis 11
4.4.4 Cancer Stem Cells 12
4.5 Diagnosis 13
4.6 Prognosis and Disease Staging 13
4.6.1 Classification 14
4.7 Introduction to Breast Cancer Treatments 15
4.8 Surgery and Radiation Therapy 16
4.9 Overview of Marketed Products for Breast Cancer 16
4.9.1 Chemotherapy 17
4.9.2 Efficacy of Chemotherapy Regimens 18
4.9.3 Hormonal Therapies 20
4.9.4 Efficacy of Endocrine Therapies 20
4.9.5 Targeted Therapies 22
4.9.6 Efficacy of Targeted Therapies 23
4.10 Treatment Guidelines 26
4.11 Current Unmet Need in the Breast Cancer Market 29

5 Assessment of Pipeline Product Innovation 31
5.1 Breast Cancer Pipeline by Phase, Molecule Type and Molecular Target 31
5.2 First-in-Class Pipeline Programs 35

6 Signaling Network, Disease Causation and Innovation Alignment 40
6.1 The complexity of signaling networks in oncology 40
6.2 Signaling pathways, disease-causing mutations and first-in-class molecular target integration 41
6.3 First-in-Class Target Matrix Assessment 43

7 First-In-Class Target Evaluation 46
7.1 Pipeline Programs which Target Protein Kinase C Delta 46
7.2 Pipeline Programs which Target p53 47
7.3 Pipeline Programs which Target FGFR4 50
7.4 Pipeline Programs which Target Akt 1, 2 and 3 51
7.5 Pipeline Programs which Target HER3 54
7.6 Pipeline Programs which Target PI3K 56
7.7 Pipeline Programs which Target Murine Double Minute 2 58
7.8 Pipeline Programs which Target Growth factor receptor-bound protein 2 60
7.9 Pipeline Programs which Target Notch-1 61
7.10 Pipeline Programs which Target Signal Transducer and Activator of Transcription 3 63
7.11 Pipeline Programs which Target Cluster of Differentiation 44 65
7.12 Pipeline Programs which Target Protein Phosphatase 2A 66
7.13 Pipeline Programs which Target Heat Shock Protein 90 68
7.14 Pipeline Programs which Target Basigin (CD147) 70
7.15 Pipeline Programs which Target Rho-associated, Coiled-coil-containing Protein Kinase 1 71
7.16 Pipeline Programs which Target Creb 73
7.17 Pipeline Programs which Target Cyclin-Dependent Kinase 4 and Cyclin-Dependent Kinase 6 74
7.18 Pipeline Programs which Target Integrin αV 77
7.19 Conclusion 79

8 Deals and Strategic Consolidations 81
8.1 Licensing Deals 81
8.1.1 Molecule Type 84
8.1.2 Mechanism of Action 86
8.2 Co-Development Deals 92
8.2.1 Molecule Type 94
8.2.2 Mechanism of Action 96
8.3 First-In-Class Molecules not Involved in Licensing or Co-Development Deals 100

9 Appendix 103
9.1 Abbreviations 103
9.2 References 103
9.3 References for Heat Map 115
9.4 Contact Us 116
9.5 Disclaimer 116


【レポート販売概要】

■ タイトル:乳癌治療のグローバル市場:画期的新薬の発見と商用化
■ 英文:Frontier Pharma: Breast Cancer - Identifying and Commercializing First-in-Class Innovation
■ 発行日:2014年7月31日
■ 調査会社:GBI Research
■ 商品コード:GBIHC336MR
■ 調査対象地域:グローバル
  • Elidel Atopic Dermatitis):市場予測と分析(~2022)
    Elidel Atopic Dermatitis) - Forecast and Market Analysis to 2022 Summary Although the past decade has seen the atopic dermatitis market remain relatively unchanged and a saturated, highly genericized arena, the coming decade could see the launch of the first biologic, which will set a precedent and pave the way for others to follow suit. Meda’s Elidel contains the molecule pimecrolimus and akin to …
  • マイクロ熱源供給システム(micro-CHP)の世界市場2019-2023
    About this market The rise in world energy demand is one of the key factors expected to trigger the micro combined heat and power (micro-CHP) market growth in the forthcoming years. Factors including the electrification of heating and transport, digitalization of modern economies, and the rise in the number of connected devices in the residential and commercial sectors have further propelled the d …
  • ビルオートメーション&制御システムの世界市場2015-2022
    According to Stratistics MRC, the Global Building Automation & Control Systems market is accounted for $46.37 billion in 2015 and is expected to reach $98.6 billion by 2022 growing at a CAGR of 11.3% from 2015 to 2022. The factors such as increasing improvements in loT transformation, huge growth in building automation centric wireless protocols, growing number of emerging countries which are deve …
  • 配電ユニットの世界市場予測(~2024年)
    “The power distribution unit market is projected to grow at a CAGR of 7.1% from 2019 to 2024” The power distribution unit market is projected to reach USD 5.2 billion by 2024 from an estimated USD 3.7 billion in 2019, at a CAGR of 7.1% during the forecast period. The rising concerns overpower stability for uninterrupted business operations, rising power distribution unit installations for reducing …
  • 石油・ガス腐食防止の世界市場分析:タイプ別(コーティング、塗料、阻害剤)、ロケーション別(オンショア、オフショア)、セクター別(上流、中流、下流)、セグメント予測、2014-2025
    The global oil & gas corrosion protection market is expected to reach USD 12.2 billion by 2025, according to a new report by Grand View Research, Inc. The market is expected to witness significant growth over the forecast period owing to rising demand from the North America region. Corrosion protection products are widely consumed in various applications sectors such as upstream, midstream and dow …
  • 世界における風力発電市場動向(Q4 2013)
    Q4 2013 Global Wind Market Update: Sudden Surge in Q4 Order Intake Summary Global wind market grew drastically in Q4 2013, with firm order intake of 7.0 GW. The US was major country to contribute in this success with a share of 46.4% in Q4 new order intake, whereas the country accounted for 32.6% of the global wind turbine order intake in 2013. The year saw reduction in Global annual installed cap …
  • 自律型無人潜水機(AUV)の世界市場予測(~2022年)
    The market for autonomous underwater vehicles (AUVs) is expected to grow from USD 211.8 Million in 2016 to USD 497.9 Million by 2022, at a CAGR of 15.31% between 2016 and 2022. The features and specifications possessed by AUVs necessary for carrying out active and vigorous research and growing importance of more reliable security measures across the globe are the key factors responsible for the gr …
  • ライトプロジェクターの世界市場2016-2020
    About Light Projector Since 2012, technological innovations have improved image resolution, increased energy efficiency, and decreased space constraints with the development of portable Pico projectors. The emergence of light projectors has ensured that even small portal projectors can display images and videos with increased clarity. Further, embedded Pico projectors are likely to dominate the Pi …
  • イオン液体の世界市場:溶媒・触媒、加工液・処理液、プラスチック、電池・電気化学、バイオリファイナリー
    The market size of ionic liquids is estimated to reach USD 39.6 Million by 2021, registering a CAGR of 9.2% between 2016 and 2021. The market is driven by rising demand for ionic liquids owing to their unique properties along with development and commercialization of ionic liquid applications. The ionic liquids find potential applications in solvents & catalysts, process & operating fluids, plasti …
  • Asthma:グローバル臨床試験レビューH2, 2013
    Asthma Global Clinical Trials Review, H2, 2013 Summary GlobalData's clinical trial report, “Asthma Global Clinical Trials Review, H2, 2013" provides data on the Asthma clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Asthma. It includes an overview of the trial numbers and their recruitment status as per the site of trial conduction ac …
  • 地上制御局(GCS)の世界市場予測(~2022年)
    The ground control station market is projected to grow from an estimated USD 2.91 Billion in 2017 to USD 5.25 Billion by 2022, at a CAGR 12.54% from 2017 to 2022. The increasing number of UAVs in commercial and military sectors is expected to drive the market. Another key factor that is going to influence this market is the growing demand for lightweight and portable ground control stations for wa …
  • スマートグリッドネットワークの世界市場2015-2019
    About Smart Grid Networking The smart grid networking platform consists of three segments: Hardware, Software, and Services. The Hardware segment includes cables, switches, in-home devices, and controllers. These devices are backed by networking software that comprises network performance monitoring management, IP address management, network traffic management, network device management, network c …
  • Enel S.p.A.:石油・ガスバリューチェーン分析レポート2013
    Enel S.p.A. Analysis Across the Oil and Gas Value Chain Report, 2013 Update Summary "Enel S.p.A." Analysis Across the Oil and Gas Value Chain is an essential source for data, analysis and strategic insight into “Enel S.p.A.”. The report provides key information relating to oil and gas assets of the company along with its operations across the value chain. The report examines the company’s business …
  • クラウドソリューション及び市場機会:Cloud Solutions and Market Opportunities
    This report bundle represents the most comprehensive research covering the market for Cloud solutions and market opportunities. It includes research that addresses competitive analysis, market opportunities in various industry verticals, cloud applications and solutions, the future of the Cloud, and more. Key Cloud Impact Areas covered includes: ■ Cloud and Commerce, Content, and Applications ■ Cl …
  • 世界の受動光ネットワーク(PON)装置市場動向(2012-2016)
    TechNavio's analysts forecast the Global Passive Optical Network (PON) Equipment market to grow at a CAGR of 23.14 percent over the period 2012-2016. One of the key factors contributing to this market growth is the increasing growth of PON equipment in China. The Global PON Equipment market has also been witnessing the development of ultra-high capacity optical networks. However, the declining ave …
※当サイトは世界の市場調査レポート紹介サイトです。市場規模、市場動向、市場予測など、多様な分析データを含むグローバル調査レポートをご案内致します。日本国内を含むアジア太平洋、中国、ヨーロッパ、アメリカ、北米、中南米、中東、アフリカ地域などにおける、製品、サービス、技術、企業(メーカー、ベンダー)、市場シェア、市場環境など多様な項目に対応致します。当サイトでご紹介するレポートは「市場調査レポート販売サイトのMarketReport.jp」でお問い合わせ及びご購入可能です。