主要先進国における膵臓癌(膵癌)治療動向(~2019)...市場調査レポートについてご紹介

【英文タイトル】Pancreatic Adenocarcinoma Therapeutics in Major Developed Markets to 2019 - Early Stage Pipeline Shows Diversity of Novel Targets though Commercial Impact Remains Distant

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【レポートの概要(一部)】

1 Table of Contents
1 Table of Contents 5
1.1 List of Tables 7
1.2 List of Figures 8
2 Introduction 9
2.1 Overview 9
2.1.1 Pancreatic Neuroendocrine Tumors 10
2.2 Pathophysiology 11
2.2.1 Inherited Disease 11
2.2.2 Somatic Mutations 11
2.3 Signs and Symptoms 12
2.4 Risk Factors 13
2.4.1 Smoking 13
2.4.2 Pancreatitis and Other Medical Conditions 13
2.4.3 Obesity 13
2.4.4 Infections 13
2.5 Diagnosis 13
2.6 Treatment Algorithm 14
2.6.1 Surgery 14
2.6.2 Radiation Therapy 14
2.6.3 Chemotherapy 15
2.6.4 Algorithm of Chemotherapeutic Treatment for Pancreatic Cancer 16
3 Marketed Products 33
3.1 Approved Products 33
3.1.1 Gemcitabine 33
3.1.2 IV Fluorouracil 34
3.1.3 Tarceva 34
3.1.4 Abraxane 35
3.1.5 Teysuno/TS-1 36
3.2 Off-Label Products 36
3.2.1 Xeloda 36
3.2.2 Eloxatin 37
3.3 Marketed Products – Discussion 37
4 Product Pipeline 39
4.1 Pipeline Overview 39
4.2 Overview of Pipeline by Phase, Route of Administration, Molecule Type and Molecular Target 39
4.3 Key Trends in Drug Development within the Pancreatic Cancer Pipeline 44
4.3.1 Enhancing Drug Delivery 44
4.3.2 Targeted Therapies 44
4.3.3 Immunotherapy 45
4.4 Clinical Trial Duration and Size 47
4.5 Clinical Trial Failure Rate 50
4.6 Clinical Trial Discussion 51
4.7 Promising Drug Candidates in Pipeline 53
4.7.1 Masivet/Kinavet (US) – AB Science 53
4.7.2 Glufosfamide – Eleison Pharmaceuticals Incorporated 54
4.7.3 Tertomotide – Kael-GemVax Co., Ltd 55
4.7.4 TH-302 – Threshold Pharmaceuticals 56
4.7.5 HyperAcute Pancreas – NewLink Genetics Corporation 58
4.7.6 MM-398 – Merrimack Pharmaceuticals Inc. 60
4.8 Pipeline Discussion 62
5 Market Forecast 67
5.1 Introduction 67
5.2 Global Market 67
5.3 North America 70
5.3.1 Treatment Usage Patterns 70
5.3.2 Annual Cost of Therapy 71
5.3.3 Market Size 73
5.4 Top Five European Countries 75
5.4.1 Treatment Usage Patterns 75
5.5 Annual Cost of Therapy 77
5.6 Market Size 79
5.7 Japan 81
5.7.1 Treatment Usage Patterns 81
5.7.2 Annual Cost of Therapy 82
5.7.3 Market Size 82
5.8 Drivers and Barriers 83
5.8.1 Drivers 83
5.8.2 Barriers 84
6 Deals 87
6.1 Licensing Deals 87
6.1.1 Clavis Enters Licensing and Development Agreement with Clovis 89
6.1.2 Baxter Enters Licensing Agreement with Onconova for Rigosertib 90
6.1.3 Lorus Therapeutics Enters Into Licensing Agreement with Zor Pharma 90
6.1.4 Novogen Enters Into Licensing Agreement with Marshall Edwards For NV-196 And NV-143 90
6.2 Co-Development Deals 90
6.2.1 Merck Serono Enters Into Co-Development Agreement with Threshold Pharma for TH-302 92
7 Appendix 93
7.1 All Pipeline Drugs by Phase 93
7.1.1 Discovery 93
7.1.2 Preclinical 95
7.1.3 IND/CTA-Filed 103
7.1.4 Phase I 103
7.1.5 Phase II 105
7.1.6 Phase III 110
7.1.7 Pre-Registration 111
7.2 Market Forecasts to 2019 111
7.2.1 Global 111
7.2.2 US 112
7.2.3 Canada 112
7.2.4 UK 113
7.2.5 France 113
7.2.6 Germany 114
7.2.7 Italy 114
7.2.8 Spain 115
7.2.9 Japan 115
7.3 Abbreviations 116
7.4 References 117
7.5 Methodology 122
7.6 Secondary Research 122
7.7 Contact Us 122
7.8 Disclaimer 122


【レポート販売概要】

■ タイトル:主要先進国における膵臓癌(膵癌)治療動向(~2019)
■ 英文:Pancreatic Adenocarcinoma Therapeutics in Major Developed Markets to 2019 - Early Stage Pipeline Shows Diversity of Novel Targets though Commercial Impact Remains Distant
■ 発行日:2014年4月14日
■ 調査会社:GBI Research
■ 商品コード:GBIHC327MR
■ 調査対象地域:グローバル
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