【レポートの概要(一部)】
1. Report Overview
1.1 Global Cholesterol-Lowering Drugs Market Overview
1.2 Global Cholesterol-Lowering Drugs Market Segmentation
1.3 Why You Should Read This Report
1.4 How This Report Delivers
1.5 Key Questions Answered by This Analytical Report
1.6 Who is This Report For?
1.7 Methodology
1.8 Frequently Asked Questions (FAQ)
1.9 Associated Visiongain Reports
1.10 About Visiongain
2. Introduction to Cholesterol-Lowering Drugs
2.1 The Pharmaceutical Industry: A Brief Overview
2.2 Cholesterol: An Essential Lipid
2.3 The Functions of Cholesterol
2.4 Metabolism and Circulation of Cholesterol
2.5 The Role of Cholesterol in Heart Disease
2.6 The Role of Cholesterol in Heart Disease: The Orthodoxy
2.6.1 The IMPROVE-IT Study
2.7 The Role of Cholesterol in Heart Disease: The Controversy
2.8 Raising HDL Cholesterol: A Worthwhile Aim?
2.9 Causes of Hypercholesterolaemia
2.9.1 Atherosclerosis
2.9.2 Dyslipidaemia, Hyperlipidaemia and Hyperlipoproteinaemia
2.9.3 Familial Hypercholesterolaemia
2.10 Treatment of Hypercholesterolaemia
2.10.1 UK Treatment Guidelines for Hypercholesterolaemia
2.10.2 US Treatment Guidelines for Hypercholesterolaemia
2.10.3 Lifestyle Changes
2.10.4 Drugs to Lower Cholesterol
2.10.5 Other Therapeutic Approaches
2.10.5.1 Partial Ileal Bypass: An Outdated Surgical Treatment
2.10.5.2 LDL Apheresis: Directly Removing Cholesterol
2.10.5.3 Liver Transplantation for Familial Hypercholesterolaemia
2.11 Classification of Cholesterol-Lowering Drugs
2.11.1 Statins
2.11.2 Selective Cholesterol Absorption Inhibitors
2.11.3 Ion Exchange Resins
2.11.4 Fibrates
2.11.5 Other Cholesterol-Lowering Drugs
2.11.6 Novel Cholesterol-Lowering Drugs
2.11.7 PCSK9 Inhibitors
2.12 Phases of Clinical Trials
2.13 Scope of This Report
2.13.1 Products Excluded from This Report
2.14 Currency Exchange Rates in This Report
3. Cholesterol-Lowering Drugs: World Market 2015-2025
3.1 The World Cholesterol-Lowering Drugs Market in 2014
3.1.1 Leading Cholesterol-Lowering Drugs Products
3.1.2 Leading Companies in the Cholesterol-Lowering Drugs Market
3.2 World Cholesterol-Lowering Drugs Market: Sales Forecast 2015-2025
3.3 Cholesterol-Lowering Drugs Market Segments: Sales Forecasts 2015-2025
3.3.1 Cholesterol-Lowering Drugs Market Segmentation
3.4 Changing Market Shares by Segment 2015-2025
3.4.1 World Cholesterol-Lowering Drugs Market: Drivers and Restraints 2015-2025
4. Leading National Markets, 2015-2025
4.1 Regional Breakdown of the World Cholesterol-Lowering Drugs Market
4.1.1 World Cholesterol-Lowering Drugs Market: Regional Forecast 2015-2025
4.1.2 How Will Regional Market Shares Change to 2025?
4.2 National Breakdown of the World Cholesterol-Lowering Drugs Market
4.2.1 World Cholesterol-Lowering Drugs Market: National Markets Forecast 2015-2025
4.2.2 How Will National Market Shares Change to 2025?
4.3 The US Cholesterol-Lowering Drugs Market 2015-2025
4.3.1 US Cholesterol-Lowering Drug Market Forecast 2015-2025
4.3.2 US Cholesterol-Lowering Drugs Market: Drivers and Restraints
4.3.2.1 High Prevalence of High Cholesterol in US
4.4 The Cholesterol-Lowering Drugs Market in the Five Leading European National Markets to 2025
4.4.1 EU5 Cholesterol-Lowering Drugs Market: Drivers and Restraints
4.4.2 The Cholesterol-Lowering Drugs Market in Germany to 2025
4.4.2.1 German Cholesterol-Lowering Drugs Market: Trends and Developments
4.4.3 The Cholesterol-Lowering Drugs Market in France to 2025
4.4.3.1 French Cholesterol-Lowering Drugs Market: Trends and Developments
4.4.4 The Cholesterol-Lowering Drugs Market in the UK to 2025
4.4.4.1 UK Cholesterol-Lowering Drugs Market: Trends and Developments
4.4.5 The Cholesterol-Lowering Drugs Market in Italy to 2025
4.4.5.1 Italian Cholesterol-Lowering Drugs Market: Trends and Developments
4.4.6 The Cholesterol-Lowering Drugs Market in Spain to 2025
4.4.6.1 Spanish Cholesterol-Lowering Drugs Market: Trends and Developments
4.5 The Cholesterol-Lowering Drugs Market in the BRIC National Markets to 2025
4.5.1 BRIC Cholesterol-Lowering Drugs Market: Drivers and Restraints
4.5.2 The Cholesterol-Lowering Drugs Market in China to 2025
4.5.2.1 Chinese Cholesterol-Lowering Drugs Market: Trends and Developments
4.5.2.1.1 Economic Challenges
4.5.2.1.2 Expansion of Healthcare Coverage and Reimbursement
4.5.3 The Cholesterol-Lowering Drugs Market in Brazil to 2025
4.5.3.1 Brazilian Cholesterol-Lowering Drugs Market: Trends and Developments
4.5.4 The Cholesterol-Lowering Drugs Market in Russia to 2025
4.5.4.1 Russian Cholesterol-Lowering Drugs Market: Trends and Developments
4.5.4.1.1 Lower Oil Prices
4.5.4.1.2 No Embargo on Foreign Drugs
4.5.5 The Cholesterol-Lowering Drugs Market in India to 2025
4.5.5.1 Indian Cholesterol-Lowering Drugs Market: Trends and Developments
4.5.5.1.1 Drug Price Control Order 2014
4.5.5.1.2 Expansion of Healthcare Provision
4.6 The Cholesterol-Lowering Drugs Market in Japan to 2025
4.6.1 Japanese Cholesterol-Lowering Drugs Market: Trends and Developments
4.6.1.1 Generic Penetration to Reach 60% by 2018?
4.6.1.2 Japanese Pharmaceutical Industry Regulatory Reform
5. Statins and Fixed-Dose Combinations: Market and Pipeline 2015-2025
5.1 Statins: Inhibiting HMG-CoA Reductase
5.2 The Statins and Fixed-Dose Combinations Market in 2014
5.3 Statins and Fixed-Dose Combinations: Market Forecast 2015-2025
5.4 How Will Market Shares of Products Change to 2025?
5.5 Crestor (Rosuvastatin, AstraZeneca)
5.5.1 Crestor: Historical Sales Estimate 2009-2014
5.5.2 Crestor: Sales Forecast 2015-2025
5.5.3 Generic Competition for Crestor
5.6 Lipitor (Atorvastatin, Pfizer)
5.6.1 Lipitor: Historical Sales Estimate 2009-2014
5.6.2 Lipitor: Sales Forecast 2015-2025
5.7 Livalo (Pitavastatin, Kowa)
5.7.1 Livalo: Sales Forecast 2015-2025
5.8 Lescol and Lescol XL (Fluvastatin, Novartis)
5.8.1 Lescol/Lescol XL: Sales Forecast 2015-2025
5.9 Zocor (Simvastatin, Merck)
5.9.1 Zocor: Sales Forecast 2015-2025
5.10 Fixed-Dose Combinations
5.11 Vytorin (Simvastatin/Ezetimibe, Merck)
5.11.1 Vytorin: Sales Forecast 2015-2025
5.12 Caduet (Atorvastatin/Amlodipine, Pfizer)
5.12.1 Caduet: Sales Forecast 2015-2025
6. Absorption Inhibitors, Ion Exchange Resins, Fibrates and Other Drugs: Market and Pipeline 2015-2025
6.1 Absorption Inhibitors, Ion Exchange Resins, Fibrates and Other Drugs: Overview
6.2 The Absorption Inhibitors, Ion Exchange Resins, Fibrates and Other Drugs Market in 2014
6.3 Absorption Inhibitors, Ion Exchange Resins, Fibrates and Other Drugs: Market Forecast 2015-2025
6.4 How Will Market Shares of Products Change to 2025?
6.5 Zetia (Ezetimibe, Merck)
6.5.1 The ENHANCE Study: No Additional Benefit
6.5.2 The IMPROVE-IT Study: Reduction in Cardiovascular Risk
6.5.3 Zetia: Sales Forecast 2015-2025
6.6 Welchol (Colesevelam, Daiichi Sankyo)
6.6.1 Threat of Imminent Generic Competition for Welchol
6.6.2 Welchol: Sales Forecast 2015-2025
6.7 Tricor (Fenofibrate, AbbVie)
6.7.1 Generic Erosion of Tricor Sales
6.7.2 Tricor: Sales Forecast 2015-2025
7. PCSK9 Inhibitors: Market and Pipeline 2015-2025
7.1 PCSK9 Inhibitors: The Next Blockbuster Drug Class?
7.2 PCSK9 in Clinical Trials
7.3 PCSK9 Inhibitors and Statins
7.4 PCSK9 Inhibitors: Market Forecast 2015-2025
7.5 How Will Market Shares of Products Change to 2025?
7.6 PCSK9 Inhibitors: Pipeline Analysis 2015-2025
7.7 Praluent (Alirocumab, Sanofi/Regeneron)
7.7.1 Praluent: Sales Forecast 2015-2025
7.8 Repatha (Evolocumab, Amgen)
7.8.1 GAUSS-2
7.8.2 RUTHERFORD-2
7.8.3 LAPLACE-2
7.8.4 Repatha: Sales Forecast 2015-2025
7.9 RN316 (Bococizumab, Pfizer)
7.9.1 RN316: Sales Forecast 2015-2025
7.10 Oral PCSK9 Inhibitor (Pfizer)
7.11 PF-06427878 (Pfizer)
7.12 PCSK9 Vaccine (Pfizer)
7.13 SX-PCK9 (Serometrix)
7.14 Discontinued Pipeline Products
7.14.1 BMS-962476 (Adnectin, Bristol-Myers Squibb)
7.14.2 LY3015014 (Eli Lilly)
8. Novel Cholesterol-Lowering Drugs: Market and Pipeline 2015-2025
8.1 Novel Cholesterol-Lowering Drugs: Overview
8.2 Novel Cholesterol-Lowering Drugs Market in 2014
8.3 Novel Cholesterol-Lowering Drugs: Market Forecast 2015-2025
8.4 How Will Market Shares of Products Change to 2025?
8.5 CETP Inhibitors: Overview
8.5.1 CETP Inhibitors: Pipeline Analysis 2015-2025
8.5.2 MK-0859 (Anacetrapib, Merck)
8.5.2.1 MK-0859 (Anacetrapib): Sales Forecast 2015-2025
8.5.3 Dalcetrapib (DalCor)
8.5.4 DEZ-001/TA-8995 (CETP Inhibitor, Dezima/Amgen)
8.5.5 DRL-17822 (CETP Inhibitor, Dr. Reddy’s Laboratories)
8.5.6 PRC-4016 (Icosabutate, ProNova BioPharma)
8.5.7 K-312 (CETP Inhibitor, Kowa)
8.6 MTTP Inhibitors: Market and Pipeline Analysis 2015-2025
8.6.1 Juxtapid (Lomitapide, Aegerion Pharmaceuticals)
8.6.1.1 Juxtapid (Lomitapide): Sales Forecast 2015-2025
8.7 ApoB Inhibitors: Market and Pipeline Analysis 2015-2025
8.7.1 Kynamro (Mipomersen, Isis Pharmaceuticals/Sanofi)
8.7.1.1 Kynamro (Mipomersen): Drug Launch and Pricing Strategy
8.7.1.2 Kynamro (Mipomersen): Sales Forecast 2015-2025
8.8 Other Drug Classes: Market and Pipeline Analysis 2015-2025
8.8.1 K-877 (PPAR-α Agonist, Kowa)
8.8.2 REGN1500 (ANGPTL3 Inhibitor, Regeneron)
8.8.3 ETC-1002 (ACL Inhibitor, Esperion Therapeutics)
8.8.4 ALN-PCS02 and ALN-PCSsc (Alnylam)
8.9 Discontinued Pipeline Products
8.9.1 Torcetrapib
8.9.2 LY2484595 (Evacetrapib)
9. Leading Companies in the Cholesterol-Lowering Drugs Market
9.1 Leading Cholesterol-Lowering Drugs Manufacturers in 2014
9.1.1 Leading Companies: Market Forecast 2015-2025
9.1.2 How Will Leading Companies’ Market Shares Change to 2025?
9.2 AstraZeneca
9.2.1 AstraZeneca: Cholesterol-Lowering Drugs
9.2.2 AstraZeneca: Sales Forecast 2015-2025
9.2.3 AstraZeneca: Recent Developments
9.2.3.1 Cholesterol Awareness Initiative in America
9.2.3.2 AstraZeneca Rejects Pfizer Takeover Bid
9.3 Merck
9.3.1 Merck: Cholesterol-Lowering Drugs
9.3.2 Merck: Sales Forecast 2015-2025
9.3.3 Merck: Recent Developments
9.3.3.1 Bayer Acquires Merck’s Consumer Health Business
9.3.3.2 Study Shows Lower LDL Levels Are More Beneficial
9.4 Pfizer
9.4.1 Pfizer: Cholesterol-Lowering Drugs
9.4.2 Pfizer: Sales Forecast 2015-2025
9.4.3 Pfizer: Recent Developments
9.4.3.1 Pfizer Ends Over-The-Counter Lipitor Program
9.4.3.2 Development of Oral PCSK9 Inhibitor
9.5 Kowa
9.5.1 Kowa: Cholesterol-Lowering Drugs
9.5.2 Kowa: Sales Forecast 2015-2025
9.5.3 Kowa: Recent Developments
9.5.3.1 Development of K-312
9.5.3.2 Development of K-887
9.6 Daiichi Sankyo
9.6.1 Daiichi Sankyo: Cholesterol-Lowering Drugs
9.6.2 Daiichi Sankyo: Sales Forecast 2015-2025
9.6.3 Daiichi Sankyo: Recent Developments
9.6.3.1 Staff Reduction at US Operation
9.7 AbbVie
9.7.1 AbbVie: Cholesterol-Lowering Drugs
9.7.2 AbbVie: Sales Forecast 2015-2025
9.7.3 AbbVie: Recent Developments
9.7.3.1 Possible Marketing Cost Reductions
9.8 Novartis
9.8.1 Novartis: Cholesterol-Lowering Drugs
9.8.2 Novartis: Sales Forecast 2015-2025
9.9 Sanofi
9.9.1 Sanofi: Cholesterol-Lowering Drugs
9.9.2 Sanofi: Sales Forecast 2015-2025
9.9.3 Sanofi: Recent Developments
9.9.3.1 Purchase of Priority Review Voucher from BioMarin Pharmaceuticals
9.10 Amgen
9.10.1 Amgen: Cholesterol-Lowering Drugs
9.10.2 Amgen: Sales Forecast 2015-2025
9.10.3 Amgen: Recent Developments
9.10.3.1 Amgen Sues Sanofi and Regeneron To Block Praluent
10. Qualitative Analysis of the Cholesterol-Lowering Drugs Market 2015-2025
10.1 SWOT Analysis of the Cholesterol-Lowering Drugs Market
10.2 Strengths
10.2.1 Strong Pipeline
10.2.2 High Profile Encouraging Healthcare Provision
10.3 Weaknesses
10.3.1 Increasing Generic Penetration
10.3.2 Approved Indications Limited for New Products
10.4 Opportunities
10.4.1 Increasing Prevalence in Emerging Markets
10.4.2 Possible Additional Indications
10.5 Threats
10.5.1 Patent Expiry
10.5.2 Cost-Containment
10.6 Porter’s Five Forces Analysis of the Cholesterol-Lowering Drugs Market
10.6.1 Rivalry among Competitors [High]
10.6.2 Threat of New Entrants [Medium]
10.6.3 Power of Suppliers [Low]
10.6.4 Power of Buyers [Medium]
10.6.5 Threat of Substitutes [High]
11. Conclusions
11.1 The World Cholesterol-Lowering Drugs Market: 2014-2015
11.2 The World Cholesterol-Lowering Drugs Market Forecast: 2014-2025
12. Glossary
【レポート販売概要】
■ タイトル:コレステロール低下剤の世界市場:PCSK9阻害薬、CETP阻害薬、MTTP阻害薬、ApoB阻害薬、PPARアゴニスト■ 英文:Cholesterol-Lowering Drugs Market Forecast 2015-2025 : Opportunities in PCSK9 Inhibitors, CETP Inhibitors, MTTP Inhibitors, ApoB Inhibitors and PPAR Agonists
■ 発行日:2015年11月
■ 調査会社:visiongain
■ 商品コード:VGAIN5112512
■ 調査対象地域:グローバル
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