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TABLE OF CONTENTS

1 INTRODUCTION 15
1.1 OBJECTIVES OF THE STUDY 15
1.2 MARKET DEFINITION 16
1.3 MARKET SEGMENTATION 16
1.3.1 MARKETS COVERED 16
1.3.2 YEARS CONSIDERED FOR THE STUDY 17
1.4 CURRENCY 18
1.5 LIMITATIONS 18
1.6 STAKEHOLDERS 18

2 RESEARCH METHODOLOGY 19
2.1 MARKET SIZE ESTIMATION 20
2.2 MARKET BREAKDOWN AND DATA TRIANGULATION 22
2.2.1 KEY DATA FROM SECONDARY SOURCES 23
2.2.2 KEY DATA FROM PRIMARY SOURCES 24
2.2.2.1 Key Industry Insights 24
2.2.3 ASSUMPTIONS FOR THE STUDY 25

3 EXECUTIVE SUMMARY 26

4 PREMIUM INSIGHTS 30
4.1 ATTRACTIVE OPPORTUNITIES IN THE PROTEIN ENGINEERING MARKET 30
4.2 PROTEIN ENGINEERING MARKET, BY END USER 31
4.3 PROTEIN ENGINEERING MARKET, BY TECHNOLOGY 32
4.4 PROTEIN ENGINEERING MARKET, BY PRODUCT 32
4.5 PROTEIN ENGINEERING MARKET GROWTH OPPORTUNITIES, BY REGION 33
4.6 LIFE CYCLE ANALYSIS, BY REGION 33

5 MARKET OVERVIEW 34
5.1 INTRODUCTION 35
5.1.1 EVOLUTION 35
5.2 MARKET DYNAMICS 36
5.2.1 DRIVERS 37
5.2.1.1 Increase in adoption of protein-based drugs over non-protein-based drugs 37
5.2.1.2 Reduction in overall timeline and cost for drug discovery 37
5.2.1.3 High prevalence rate of lifestyle diseases 37
5.2.1.4 Growth in funding for protein engineering 37
5.2.2 RESTRAINTS 38
5.2.2.1 Expensive and high-maintenance tools and instruments used in protein engineering 38
5.2.3 OPPORTUNITIES 39
5.2.3.1 Significant growth prospects in developing countries 39
5.2.3.2 Protein therapy as an alternative to gene therapy 39
5.2.3.3 Top-selling biologics drugs going off–patent in the near future 39
5.2.4 CHALLENGES 40
5.2.4.1 Need for qualified researchers and mandatory training in protein engineering increases cost of process 40
5.2.5 WINNING IMPERATIVE 41
5.2.5.1 Site-directed mutagenesis is a breakthrough technology augmenting the growth of the protein engineering market 41

6 INDUSTRY INSIGHTS 42
6.1 INTRODUCTION 42
6.2 SUPPLY CHAIN ANALYSIS 42
6.2.1 KEY INFLUENCERS 43
6.3 PORTER’S FIVE FORCES ANALYSIS 44
6.3.1 THREAT OF NEW ENTRANTS 44
6.3.2 THREAT OF SUBSTITUTES 44
6.3.3 BARGAINING POWER OF BUYERS 45
6.3.4 BARGAINING POWER OF SUPPLIERS 45
6.3.5 INTENSITY OF RIVALRY 45
6.4 STRATEGIC BENCHMARKING 45
6.4.1 NEW PRODUCT LAUNCHES 45

7 PROTEIN ENGINEERING MARKET, BY PRODUCT 47
7.1 INTRODUCTION 48
7.2 INSTRUMENTS 49
7.2.1 REAGENTS 51
7.3 SERVICES & SOFTWARE 53

8 PROTEIN ENGINEERING MARKET, BY TECHNOLOGY 55
8.1 INTRODUCTION 56
8.2 RATIONAL PROTEIN DESIGN 58
8.3 IRRATIONAL PROTEIN DESIGN 60

9 PROTEIN ENGINEERING MARKET, BY PROTEIN TYPE 62
9.1 INTRODUCTION 63
9.2 MONOCLONAL ANTIBODIES 64
9.3 INSULIN 66
9.4 ERYTHROPOIETIN 68
9.5 INTERFERONS 70
9.6 COLONY STIMULATING FACTORS 71
9.7 GROWTH HORMONES 73
9.8 COAGULATION FACTORS 74
9.9 VACCINES 76
9.10 OTHER PROTEINS 77

10 PROTEIN ENGINEERING MARKET, BY END USER 79
10.1 INTRODUCTION 80
10.2 ACADEMIC RESEARCH INSTITUTES 81
10.3 PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES 84
10.4 CONTRACT RESEARCH ORGANIZATIONS 85

11 PROTEIN ENGINEERING MARKET, BY REGION 87
11.1 INTRODUCTION 88
11.2 NORTH AMERICA 90
11.3 U.S. 93
11.3.1 CANADA 96
11.4 EUROPE 99
11.5 ASIA 102
11.5.1 CHINA 105
11.5.2 INDIA 107
11.5.3 JAPAN 109
11.5.4 REST OF ASIA (ROA) 111
11.6 ROW 113

12 COMPETITIVE LANDSCAPE 116
12.1 OVERVIEW 117
12.2 BATTLE FOR MARKET SHARE: NEW PRODUCT LAUNCHES WAS THE KEY GROWTH STRATEGY ADOPTED BY MARKET PLAYERS 118
12.3 NEW PRODUCT LAUNCHES 118
12.4 AGREEMENTS, PARTNERSHIPS, AND COLLABORATIONS 119
12.5 EXPANSIONS 120
12.6 ACQUISITIONS 121

13 COMPANY PROFILES 122
(Overview, Financials, Products & Services, Strategy, & Developments)*
13.1 INTRODUCTION 122
13.2 AGILENT TECHNOLOGIES, INC. 123
13.3 BIO-RAD LABORATORIES, INC. 126
13.4 BRUKER CORPORATION 128
13.5 AB SCIEX (A SUBSIDIARY OF DANAHER CORPORATION) 131
13.6 GE HEALTHCARE 134
13.7 GENSCRIPT USA, INC. 136
13.8 PERKINELMER, INC. 138
13.9 SIGMA-ALDRICH CORPORATION 141
13.10 THERMO FISHER SCIENTIFIC, INC. 143
13.11 WATERS CORPORATION 146
*Details on Financials, Product & Services, Strategy, & Developments might not be captured in case of unlisted companies.

14 APPENDIX 149
14.1 INSIGHTS OF INDUSTRY EXPERTS 149
14.2 DISCUSSION GUIDE 149
14.3 RECENT DEVELOPMENTS 151
14.4 INTRODUCING RT: REAL-TIME MARKET INTELLIGENCE 153
14.5 AVAILABLE CUSTOMIZATIONS 154
14.6 RELATED REPORTS 155