【レポートの概要（一部）】
Table of Contents
Table of Contents 2
List of Tables 7
List of Figures 8
Introduction 9
Global Markets Direct Report Coverage 9
Dyskinesia Overview 10
Therapeutics Development 11
Pipeline Products for Dyskinesia – Overview 11
Pipeline Products for Dyskinesia – Comparative Analysis 12
Dyskinesia – Therapeutics under Development by Companies 13
Dyskinesia – Therapeutics under Investigation by Universities/Institutes 16
Dyskinesia – Pipeline Products Glance 17
Late Stage Products 17
Clinical Stage Products 18
Early Stage Products 19
Dyskinesia – Products under Development by Companies 20
Dyskinesia – Products under Investigation by Universities/Institutes 23
Dyskinesia – Companies Involved in Therapeutics Development 24
Adamas Pharmaceuticals, Inc. 24
Addex Therapeutics Ltd 25
Advicenne Pharma 26
Amarantus Bioscience Holdings, Inc. 27
Astraea Therapeutics, LLC 28
Auspex Pharmaceuticals, Inc. 29
BioMarin Pharmaceutical Inc. 30
Catalyst Pharmaceutical Partners, Inc. 31
Contera Pharma ApS 32
EpiVax, Inc. 33
Heptares Therapeutics Ltd. 34
Integrative Research Laboratories Sweden AB 35
Ipsen S.A. 36
Medicure Inc. 37
Medy-Tox Inc. 38
Merz Pharmaceuticals GmbH 39
Neurim Pharmaceuticals Ltd 40
Neurocrine Biosciences, Inc. 41
Neurolixis Inc. 42
Novartis AG 43
Osmotica Pharmaceutical Corp. 44
Otsuka Holdings Co., Ltd. 45
Santhera Pharmaceuticals Holding AG 46
SciFluor Life Sciences, LLC 47
Synchroneuron Inc. 48
Targacept, Inc. 49
Upsher-Smith Laboratories, Inc. 50
Dyskinesia – Therapeutics Assessment 51
Assessment by Monotherapy Products 51
Assessment by Combination Products 52
Assessment by Target 53
Assessment by Mechanism of Action 55
Assessment by Route of Administration 57
Assessment by Molecule Type 59
Drug Profiles 61
(dextromethorphan hydrobromide + quinidine sulfate) – Drug Profile 61
Product Description 61
Mechanism of Action 61
R&D Progress 61
abobotulinumtoxin A – Drug Profile 63
Product Description 63
Mechanism of Action 63
R&D Progress 63
abobotulinumtoxin A next generation – Drug Profile 65
Product Description 65
Mechanism of Action 65
R&D Progress 65
acamprosate calcium SR – Drug Profile 66
Product Description 66
Mechanism of Action 66
R&D Progress 66
ADV-6979 – Drug Profile 68
Product Description 68
Mechanism of Action 68
R&D Progress 68
amantadine hydrochloride ER – Drug Profile 69
Product Description 69
Mechanism of Action 69
R&D Progress 69
amantadine hydrochloride ER – Drug Profile 71
Product Description 71
Mechanism of Action 71
R&D Progress 71
AQW-051 – Drug Profile 72
Product Description 72
Mechanism of Action 72
R&D Progress 72
AT-127 – Drug Profile 73
Product Description 73
Mechanism of Action 73
R&D Progress 73
AT-326 – Drug Profile 74
Product Description 74
Mechanism of Action 74
R&D Progress 74
AT-403 – Drug Profile 75
Product Description 75
Mechanism of Action 75
R&D Progress 75
AVP-786 – Drug Profile 76
Product Description 76
Mechanism of Action 76
R&D Progress 76
befiradol – Drug Profile 78
Product Description 78
Mechanism of Action 78
R&D Progress 78
CPP-115 – Drug Profile 79
Product Description 79
Mechanism of Action 79
R&D Progress 79
dipraglurant ER – Drug Profile 81
Product Description 81
Mechanism of Action 81
R&D Progress 81
dipraglurant IR – Drug Profile 82
Product Description 82
Mechanism of Action 82
R&D Progress 82
Drugs for Dyskinesia – Drug Profile 83
Product Description 83
Mechanism of Action 83
R&D Progress 83
Drugs for Tardive Dyskinesia – Drug Profile 84
Product Description 84
Mechanism of Action 84
R&D Progress 84
dutetrabenazine ER – Drug Profile 85
Product Description 85
Mechanism of Action 85
R&D Progress 85
eltoprazine – Drug Profile 86
Product Description 86
Mechanism of Action 86
R&D Progress 86
fipamezole – Drug Profile 88
Product Description 88
Mechanism of Action 88
R&D Progress 88
HTL-14242 – Drug Profile 90
Product Description 90
Mechanism of Action 90
R&D Progress 90
IRL-790 – Drug Profile 91
Product Description 91
Mechanism of Action 91
R&D Progress 91
JM-010 – Drug Profile 92
Product Description 92
Mechanism of Action 92
R&D Progress 92
MRZ-8676 – Drug Profile 93
Product Description 93
Mechanism of Action 93
R&D Progress 93
naluzotan – Drug Profile 94
Product Description 94
Mechanism of Action 94
R&D Progress 94
Neu-120 – Drug Profile 95
Product Description 95
Mechanism of Action 95
R&D Progress 95
Neu-240 – Drug Profile 96
Product Description 96
Mechanism of Action 96
R&D Progress 96
onabotulinumtoxin A – Drug Profile 97
Product Description 97
Mechanism of Action 97
R&D Progress 97
onabotulinumtoxin A – Drug Profile 98
Product Description 98
Mechanism of Action 98
R&D Progress 98
PEUN-3 – Drug Profile 99
Product Description 99
Mechanism of Action 99
R&D Progress 99
RG-2833 – Drug Profile 100
Product Description 100
Mechanism of Action 100
R&D Progress 100
Small Molecule for Dyskinesia – Drug Profile 102
Product Description 102
Mechanism of Action 102
R&D Progress 102
Small Molecule for Dyskinesia and Hyperkinesia – Drug Profile 103
Product Description 103
Mechanism of Action 103
R&D Progress 103
Small Molecules to Antagonize Metabotropic Glutamate Receptor 5 (mGluR5) for Dyskinesia – Drug Profile 104
Product Description 104
Mechanism of Action 104
R&D Progress 104
Tardoxal – Drug Profile 105
Product Description 105
Mechanism of Action 105
R&D Progress 105
TC-8831 – Drug Profile 106
Product Description 106
Mechanism of Action 106
R&D Progress 106
valbenazine – Drug Profile 107
Product Description 107
Mechanism of Action 107
R&D Progress 107
Dyskinesia – Recent Pipeline Updates 109
Dyskinesia – Dormant Projects 136
Dyskinesia – Discontinued Products 138
Dyskinesia – Product Development Milestones 139
Featured News & Press Releases 139
Feb 10, 2015: Amarantus Announces Publication in BRAIN of Eltoprazine Phase 2a Clinical Study for Treating Parkinson’s Disease Levodopa-Induced Dyskinesia 139
Feb 09, 2015: Adamas Pharmaceuticals’ Phase 2/3 Clinical Study Published in Movement Disorders 140
Feb 03, 2015: Auspex Pharmaceuticals Completes Enrollment in a Pivotal Clinical Trial of SD-809 in Tardive Dyskinesia 141
Jan 19, 2015: Addex and Dystonia Medical Research Foundation Announce Partnership to Explore the Therapeutic use of Dipraglurant in the Treatment of Dystonia 142
Jan 12, 2015: Auspex Announces Favorable Topline Results From Thorough QT Clinical Trial of SD-809 143
Jan 08, 2015: Amarantus to Participate in the Eighth Annual OneMedForum Conference on January 12 – 13, 2015 144
Oct 30, 2014: Auspex Pharmaceuticals Initiates Second Pivotal Clinical Trial for SD-809 in Tardive Dyskinesia 144
Oct 30, 2014: Neurocrine Biosciences Receives Breakthrough Therapy Designation for NBI-98854 in Tardive Dyskinesia 145
Oct 28, 2014: Adamas Pharmaceuticals Expands Its Phase 3 Program With ADS-5102 for the Treatment of Levodopa-induced Dyskinesia in Patients With Parkinson’s Disease 146
Oct 20, 2014: Neurocrine Announces Initiation Of Phase III Study For VMAT2 Inhibitor NBI-98854 147
Appendix 148
Methodology 148
Coverage 148
Secondary Research 148
Primary Research 148
Expert Panel Validation 148
Contact Us 148
Disclaimer 149
【レポート販売概要】
■ タイトル：ジスキネジア(Dyskinesia)：治療薬開発パイプライン動向（2015年上半期版）■ 英文：Dyskinesia - Pipeline Review, H1 2015
■ 発行日：2015年3月11日
■ 調査会社：Global Markets Direct
■ 商品コード：GMDHC6258IDB
■ 調査対象地域：グローバル
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