【レポートの概要(一部)】
Table of Contents
Table of Contents 2
List of Tables 8
List of Figures 9
Introduction 10
Global Markets Direct Report Coverage 10
Coronary Artery Disease (CAD) (Ischemic Heart Disease) Overview 11
Therapeutics Development 12
Pipeline Products for Coronary Artery Disease (CAD) (Ischemic Heart Disease) – Overview 12
Pipeline Products for Coronary Artery Disease (CAD) (Ischemic Heart Disease) – Comparative Analysis 13
Coronary Artery Disease (CAD) (Ischemic Heart Disease) – Therapeutics under Development by Companies 14
Coronary Artery Disease (CAD) (Ischemic Heart Disease) – Therapeutics under Investigation by Universities/Institutes 17
Coronary Artery Disease (CAD) (Ischemic Heart Disease) – Pipeline Products Glance 18
Late Stage Products 18
Clinical Stage Products 19
Early Stage Products 20
Unknown Stage Products 21
Coronary Artery Disease (CAD) (Ischemic Heart Disease) – Products under Development by Companies 22
Coronary Artery Disease (CAD) (Ischemic Heart Disease) – Products under Investigation by Universities/Institutes 25
Coronary Artery Disease (CAD) (Ischemic Heart Disease) – Companies Involved in Therapeutics Development 26
AnGes MG, Inc. 26
AstraZeneca PLC 27
Bayer AG 28
Biosidus S.A. 29
Biscayne Pharmaceuticals, Inc. 30
Bristol-Myers Squibb Company 31
Cardiome Pharma Corp 32
CardioVascular BioTherapeutics, Inc. 33
Eagle Pharmaceuticals, Inc. 34
Gilead Sciences, Inc. 35
Hemostemix Ltd 36
Human Stem Cells Institute 37
Isis Pharmaceuticals, Inc. 38
Juventas Therapeutics, Inc. 39
Lacer, S.A. 40
Lee’s Pharmaceutical Holdings Limited 41
Lonestar Heart, Inc. 42
MedImmune, LLC 43
Merck & Co., Inc. 44
Miltenyi Biotec GmbH 45
Multi Gene Vascular Systems Ltd 46
Nuo Therapeutics, Inc. 47
Pluristem Therapeutics Inc. 48
Regado Biosciences, Inc. 49
The Medicines Company 50
ViroMed Co., Ltd. 51
Coronary Artery Disease (CAD) (Ischemic Heart Disease) – Therapeutics Assessment 52
Assessment by Monotherapy Products 52
Assessment by Target 53
Assessment by Mechanism of Action 55
Assessment by Route of Administration 57
Assessment by Molecule Type 59
Drug Profiles 61
ACP-01 – Drug Profile 61
Product Description 61
Mechanism of Action 61
R&D Progress 61
ALD-201 – Drug Profile 63
Product Description 63
Mechanism of Action 63
R&D Progress 63
anacetrapib – Drug Profile 64
Product Description 64
Mechanism of Action 64
R&D Progress 64
Aptamers for Cardiovascular Diseases – Drug Profile 66
Product Description 66
Mechanism of Action 66
R&D Progress 66
BAY-606583 – Drug Profile 67
Product Description 67
Mechanism of Action 67
R&D Progress 67
beperminogene perplasmid – Drug Profile 68
Product Description 68
Mechanism of Action 68
R&D Progress 68
Biglycan Therapy for Cardiovascular Diseases – Drug Profile 73
Product Description 73
Mechanism of Action 73
R&D Progress 73
BIS-5409 – Drug Profile 74
Product Description 74
Mechanism of Action 74
R&D Progress 74
bivalirudin – Drug Profile 75
Product Description 75
Mechanism of Action 75
R&D Progress 75
bivalirudin – Drug Profile 76
Product Description 76
Mechanism of Action 76
R&D Progress 76
BQ-123 – Drug Profile 78
Product Description 78
Mechanism of Action 78
R&D Progress 78
C2 ceramide – Drug Profile 80
Product Description 80
Mechanism of Action 80
R&D Progress 80
C6 ceramide – Drug Profile 81
Product Description 81
Mechanism of Action 81
R&D Progress 81
cangrelor – Drug Profile 82
Product Description 82
Mechanism of Action 82
R&D Progress 82
CAP-1002 – Drug Profile 84
Product Description 84
Mechanism of Action 84
R&D Progress 84
Cryocell – Drug Profile 86
Product Description 86
Mechanism of Action 86
R&D Progress 86
CVBT-141H – Drug Profile 87
Product Description 87
Mechanism of Action 87
R&D Progress 87
Gemacell – Drug Profile 89
Product Description 89
Mechanism of Action 89
R&D Progress 89
Gene Therapy to Activate Vascular Endothelial Growth Factor for Cardiovascular Diseases – Drug Profile 90
Product Description 90
Mechanism of Action 90
R&D Progress 90
Gene Therapy to Activate VEGF for Ischemia – Drug Profile 91
Product Description 91
Mechanism of Action 91
R&D Progress 91
ISIS-APOARx – Drug Profile 92
Product Description 92
Mechanism of Action 92
R&D Progress 92
ISIS-CRPRx – Drug Profile 93
Product Description 93
Mechanism of Action 93
R&D Progress 93
JVS-100 – Drug Profile 94
Product Description 94
Mechanism of Action 94
R&D Progress 94
LA-419 – Drug Profile 96
Product Description 96
Mechanism of Action 96
R&D Progress 96
MEDI-6012 – Drug Profile 97
Product Description 97
Mechanism of Action 97
R&D Progress 97
Monoclonal Antibody to Inhibit CD20 for Cardiovascular Disease – Drug Profile 99
Product Description 99
Mechanism of Action 99
R&D Progress 99
MultiGeneGraft – Drug Profile 100
Product Description 100
Mechanism of Action 100
R&D Progress 100
MZ-004 – Drug Profile 101
Product Description 101
Mechanism of Action 101
R&D Progress 101
Oligonucleotides for Ischemic Heart Disease and Duchenne Muscular Dystrophy – Drug Profile 103
Product Description 103
Mechanism of Action 103
R&D Progress 103
Proteins for Ischemic Heart Disease – Drug Profile 104
Product Description 104
Mechanism of Action 104
R&D Progress 104
ranolazine ER – Drug Profile 105
Product Description 105
Mechanism of Action 105
R&D Progress 105
rivaroxaban – Drug Profile 107
Product Description 107
Mechanism of Action 107
R&D Progress 107
Small Molecule for Coronary Artery Disease – Drug Profile 112
Product Description 112
Mechanism of Action 112
R&D Progress 112
Stem Cell Therapy for Cardiovascular Disease – Drug Profile 113
Product Description 113
Mechanism of Action 113
R&D Progress 113
Stem Cell Therapy for Cardiovascular Diseases – Drug Profile 115
Product Description 115
Mechanism of Action 115
R&D Progress 115
Synthetic Peptides to Modulate CD36 Receptor for Ischemic Heart Disease and Macular Degeneration – Drug Profile 117
Product Description 117
Mechanism of Action 117
R&D Progress 117
tirofiban hydrochloride – Drug Profile 119
Product Description 119
Mechanism of Action 119
R&D Progress 119
VM-202 – Drug Profile 121
Product Description 121
Mechanism of Action 121
R&D Progress 121
XL-652 – Drug Profile 123
Product Description 123
Mechanism of Action 123
R&D Progress 123
ZK-001 – Drug Profile 125
Product Description 125
Mechanism of Action 125
R&D Progress 125
Coronary Artery Disease (CAD) (Ischemic Heart Disease) – Recent Pipeline Updates 127
Coronary Artery Disease (CAD) (Ischemic Heart Disease) – Dormant Projects 155
Coronary Artery Disease (CAD) (Ischemic Heart Disease) – Discontinued Products 158
Coronary Artery Disease (CAD) (Ischemic Heart Disease) – Product Development Milestones 159
Featured News & Press Releases 159
Nov 14, 2014: The Medicines Company to Present New Data on Investigational Antiplatelet Agent Cangrelor at 2014 AHA Annual Scientific Sessions in Chicago 159
Oct 27, 2014: The Medicines Company Wins Favorable Judgment in Angiomax (Bivalirudin) Patent Litigation 159
Oct 06, 2014: Capricor Announces Plans to Pursue Clinical Program for the Treatment of Duchenne Muscular Dystrophy With Cardiosphere-Derived Cells (CDCs) 160
Sep 02, 2014: Isis Pharmaceuticals Presents Data On ISIS-APO(A)RX At European Society of Cardiology Congress 2014 160
Jul 07, 2014: The Medicines Company Receives Market Authorization Renewal for Angiox (Bivalirudin) from the European Medicines Agency and the European Commission 161
Apr 28, 2014: The Medicines Company Files Petition Against Aurobindo Over Patent Infringement 162
Mar 30, 2014: Analysis of EUROMAX and HORIZONS-AMI Trials of The Medicines Company’s Angiomax Presented at ACC.14 162
Dec 23, 2013: European Medicines Agency Accepts Marketing Authorization Application for The Medicines Company’s Cangrelor 163
Oct 11, 2013: Medicure Announces Approval of Recommended Dosing Regimen for AGGRASTAT 164
Oct 09, 2013: First Patient Enrolled in Phase III Trial Evaluating The Medicines Company’s Angiomax in Patients Undergoing Peripheral Endovascular Procedures 164
Appendix 166
Methodology 166
Coverage 166
Secondary Research 166
Primary Research 166
Expert Panel Validation 166
Contact Us 167
Disclaimer 167
【レポート販売概要】
■ タイトル:冠動脈疾患(CAD)(虚血性心疾患)の治療薬パイプライン動向(2015年上半期版)■ 英文:Coronary Artery Disease (CAD) (Ischemic Heart Disease) - Pipeline Review, H1 2015
■ 発行日:2015年1月22日
■ 調査会社:Global Markets Direct
■ 商品コード:GMDHC6034IDB
■ 調査対象地域:グローバル
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