【レポートの概要(一部)】
1 Table of Contents
1 Table of Contents 4
1.1 List of Tables 7
1.2 List of Figures 7
2 Introduction 8
2.1 Catalyst 8
2.2 Related Reports 9
2.3 Upcoming Related Reports 11
3 Disease Overview 12
3.1 Etiology and Pathophysiology 12
3.1.1 Etiology 12
3.1.2 Pathophysiology 13
3.1.3 Prognosis and Quality of Life 15
3.2 Symptoms 17
3.2.1 Hemophilia A and B 17
3.2.2 Inhibitors 18
4 Disease Management 19
4.1 Treatment Overview 19
4.1.1 Hemophilia A and B Diagnosis 20
4.1.2 Hemophilia A and B Treatment 20
4.1.3 Inhibitors Diagnosis 22
4.1.4 Inhibitors Treatment 22
5 Competitive Assessment 24
5.1 Overview 24
5.2 Strategic Competitive Assessment 25
6 Opportunity and Unmet Need 29
6.1 Overview 29
6.2 Opportunities Analysis 30
6.2.1 Longer-Lasting Recombinant Factors to Reduce the Frequency of Prophylactic Injections 30
6.2.2 Lower-Cost Recombinant Replacement Therapies 31
6.2.3 Lower Risk of Inhibitor Formation in Previously Untreated Patients 32
6.2.4 More Convenient Drug Administration 32
6.2.5 Oral Formulation of Recombinant Replacement Therapies 33
6.3 Unmet Needs Gap Analysis 33
6.3.1 Long-Acting FVIII Replacement Therapies 33
6.3.2 Gene Therapy Treatments for Hemophilia A and B 34
7 Pipeline Assessment 35
7.1 Overview 35
7.2 Promising Drugs in Clinical Development – Hemophilia A 35
7.3 Promising Drugs in Clinical Development – Hemophilia B 37
7.4 Promising Drugs in Clinical Development – Hemophilia A and B Patients with Inhibitors 39
8 Alprolix (rFIXFc) 40
8.1 Overview 40
8.2 Efficacy 41
8.3 Safety 41
8.4 Dosing and Formulation 41
8.5 Potential Clinical Positioning 42
8.6 Potential Commercial Positioning 42
8.7 Pricing and Reimbursement 43
8.8 SWOT Analysis 43
8.9 Forecast 44
9 Appendix 45
9.1 Bibliography 45
9.2 Abbreviations 48
9.3 Methodology 50
9.4 Forecasting Methodology 50
9.4.1 Diagnosed Hemophilia Patients 50
9.4.2 Percent Drug-Treated Patients 51
9.4.3 General Pricing Assumptions 51
9.4.4 Pricing of Pipeline Agents 52
9.5 Physicians and Specialists Included in this Study 53
9.6 About the Authors 56
9.6.1 Authors 56
9.6.2 Global Head of Healthcare 57
9.7 About GlobalData 58
9.8 Disclaimer 58
【レポート販売概要】
■ タイトル:Alprolix (Hemophilia A and B):市場予測と分析(~2022)■ 英文:Alprolix (Hemophilia A and B) - Forecast and Market Analysis to 2022
■ 発行日:2013年11月30日
■ 調査会社:GlobalData
■ 商品コード:GDATA403162722
■ 調査対象地域:グローバル
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