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Executive Summary
E.1 Smart Antimicrobials: Technology Directions
E.1.1 The Meaning of Smart Antimicrobials
E.1.2 Smarter Microbes Need Smarter Antimicrobials
E.2 Healthcare: First Target for Smart Antimicrobials
E.3 Smart Antimicrobials in non-Healthcare Markets
E.3.1 Challenges to Smart Antimicrobials in non-Healthcare Markets
E.3.2 Marketing Strategies for Smart Antimicrobials in non-Healthcare Markets
E.4 Summary of Eight-Year Forecasts of Smart Antimicrobials
E.5 Seven Companies to Watch in the Smart Antimicrobial Market
E.5.1 BASF: Has Important Pieces of the Smart Antimicrobial Puzzle
E.5.2 Dow Chemical: Possibly Moving Beyond Silvadur
E.5.3 DSM Biomedical: Moving Close to a Smart Antimicrobial Offering
E.5.4 Life Material Technology: Openly Smart
E.5.5 Microban: An Antimicrobial Branding Strategy
E.5.6 Sciessent: Smarts and Branding
E.5.7 Nolla: Beyond Nanosilver

Chapter One: Introduction
1.1 Background to this Report
1.1.1 The Selective Killing of Microbes: A Role for Smart Materials
1.1.2 Smart Polymers and Smart Antimicrobials
1.1.3 Self-Cleaning Antimicrobials
1.1.4 Antimicrobials and Super-hydrophobic Materials
1.1.5 Nanotechnology and Antimicrobials: Advanced Functionality, Smartness and Competition
1.1.6 The Bottom Line: A Roadmap for Smart Antimicrobials
1.2 Objectives and Scope of this Report
1.3 Methodology for this Report
1.4 Plan of this Report

Chapter Two: Smart Antimicrobial Technology Trends
2.1 Antimicrobial Materials Trends: Impact on the Need for Smart Antimicrobials
2.1.1 Mechanisms and Focus
2.1.2 Smart Antimicrobials are Needed Now: The Business Case for Developing Smart Antimicrobial Materials
2.1.3 The Downside of Smart Antimicrobials: Negatives and Uncertainties
2.2 The Selective Killing of Microbes: A Role for Smart Materials
2.2.1 The Role of Peptides
2.2.2 Other Selective Antimicrobials
2.3 Smart Polymers and Smart Antimicrobials Together at Last
2.3.1 Polymers are Highly Suitable for Smart Surfaces
2.3.2 Antimicrobial Polymers Today
2.3.3 Smart Antimicrobial Polymers: Self-Healing Antimicrobials and Hydrogels
2.4 Self-Cleaning Antimicrobials
2.5 Antimicrobials and Super-hydrophobic Materials
2.6 Nanotechnology and Antimicrobials: Advanced Functionality, Smartness and Competition
2.7 Key Points from this Chapter

Chapter Three: Antimicrobial Coatings and Surfaces in Healthcare
3.1 Antimicrobial Action: Where the Medical Surfaces Are
3.1.1 Desperately Seeking Smarts
3.2 Drivers for New Antimicrobial Approaches in Healthcare Facilities
3.2.1 Hospital-Acquired Infections
3.2.2 The Rise of Super Strain-Resistant Pathogens
3.2.3 The Need for Synergy: Cleaning and Antimicrobial Strategies in Healthcare Facilities
3.3 Options for Medical/Healthcare-specific Smart Antimicrobial Coatings and Surfaces
3.3.1 Silver Nanoparticles
3.3.2 Antimicrobial Peptides
3.3.3 Textured Biomaterial Surfaces
3.3.4 Hydrogels for Bioactive Coatings
3.3.5 Physical Mechanisms for Antimicrobials
3.4 Targets for Smart Antimicrobials
3.4.1 The Need for Smart Antimicrobials Implanted Devices
3.4.2 Equipment, Devices and Smart Antimicrobials
3.4.3 Facilities: Which Ones are Critical for Smart Antimicrobial Surfaces?
3.4.4 Clothing and Textiles
3.5 Challenges and Opportunities
3.5.1 Biocompatibility
3.5.2 Environmental Concerns
3.6 Eight-Year Forecasts of Smart Antimicrobials in Healthcare Markets
3.7 Companies to Watch in Smart Antimicrobial Materials in Medical/Healthcare
3.7.1 Aegis Intelligent Chemicals
3.7.2 Bio-Gate
3.7.3 Biotech International (U.K.)
3.7.4 Dow Chemical (U.S.)
3.7.5 DSM Biomedical (U.S.)
3.7.6 Life Material Technology
3.7.7 Microban
3.7.8 Dunmore
3.7.9 Parker Hannefin (U.S.)
3.7.10 Sciessent (U.S.)
3.7.11 Start-ups We’re Tracking
3.8 Key Points from This Chapter

Chapter Four: Smart Antimicrobials in Non-Medical Applications
4.1 Beyond Healthcare: Where Can Smart Antimicrobials be Sold?
4.1.1 The “Ick Factor” as a Persuasive Driver for Smart Antimicrobials
4.1.2 Cost, Value and Multi-functionality
4.1.3 Defining Smart Antimicrobials Downwards: Can’t-reach Areas
4.1.4 Regulatory Concerns for Smart Antimicrobials in non-Healthcare Markets
4.2 Smart Antimicrobials in Consumer Electronics and Appliances: Clean Touch
4.2.1 Touch Means Microbes – and Antimicrobials
4.2.2 Three Uses for Smart Antimicrobials for Consumer Electronics and Appliances
4.2.3 What Kinds of Smart Antimicrobials will be used in Consumer Electronics and Appliances: An Eight-Year Forecast
4.3 Clothing and Textiles: A Need for Smarts?
4.3.1 Key Requirements for Antimicrobials for Textiles and Clothing
4.3.2 Silver: Smart Antimicrobial of Choice for Textiles and Clothing
4.3.3 Titanium Dioxide (TiO2)-coated Fabrics: Photocatalysis as Smart Antimicrobials
4.3.4 Other Possibilities: Fluorochemicals, Organilisanes and Superhydrophobia
4.3.5 Limitations to Smart Antimicrobials in Textiles
4.3.6 An Eight-Year Forecast of Smart Antimicrobials in Textiles and Clothing
4.4 Links in a Supply Chain: Smart Antimicrobials in Food, Water, and Agriculture
4.4.1 Food Processing
4.4.2 Water Filtration
4.4.3 An Eight-Year Forecast of Smart Antimicrobials in the Food and Water Supply
4.5 Smart Antimicrobial Applications in Buildings
4.5.1 Making Sense of the Business Case
4.5.2 Building Components: A Tough Sell—Maybe
4.6 Transportation: Cars, Boats and Planes
4.6.1 Areas Where there is a Compelling Case for Using Smart Antimicrobials in Transportation
4.6.2 Smart Antimicrobials and the Automotive Surface Imperative
4.7 Military and Smart Antimicrobials: A Wide Net
4.8 Companies to Watch
4.8.1 Microban (U.S.)
4.8.2 Sciessent (U.S.)
4.8.3 Polygiene (Sweden)
4.8.4 Gelest (U.S.)
4.8.5 AK Coatings (U.S.)
4.8.6 Americhem (U.S.)
4.8.7 BASF (Germany)
4.8.8 Dow Chemical (U.S.)
4.8.9 Nolla (Andorra)
4.8.10 Parx Plastics (Netherlands)
4.8.11 PPG Architectural Coatings (U.S.)
4.9 Key Points from This Chapter
Acronyms and Abbreviations Used In this Report
About the Authors