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1. Report Overview
1.1 Cell-Based Assays: Overview
1.2 Cell-Based Assays Market Segmentation
1.3 Why You Should Read This Report
1.4 How this Report Delivers
1.5 Questions Answered by this Report
1.6 Who is this Report for?
1.7 Research and Analysis Methods
1.8 Frequently Asked Questions (FAQ)
1.9 Associated Reports
1.10 About Visiongain

2. Introduction to Cell-Based Assays and Applications
2.1 Cost of New Drug Discovery and Development Reaches $2.6bn – Companies Constantly Looking for Increased Efficiencies
2.2 Drug Discovery Approaches- Target-Based and Phenotype-Based Discovery
2.3 Drug Screening Assays
2.4 Animal Models: In Vivo Conditions, but Results May Not Be Transferable to People
2.5 Biochemical Assays and their Advantages over Animal Models
2.5.1 Applications of Biochemical Assays
2.5.2 Lead Identification and Toxicity Testing
2.6 Cell-Based Assays and their Advantages
2.7 2D vs 3D Cell-Based Assays
2.8 The Different Assay Detection Methods and Technologies
2.9 Cells Used in Cell-Based Assays
2.9.1 Immortalised Cell Lines – Convenient but not Truly Representative of Normal Human Cells
2.9.2 Primary Cells: Closer to the In Vivo Environment, but Short Supply
2.9.3 Stem Cells: Potential to Overcome Limitations of Primary Cells and Immortalised Cell Lines
2.10 Uses for Cell-Based Assays in Drug Discovery and Development
2.10.1 Target Validation
2.10.2 Primary Screening
2.10.3 Secondary Screening
2.10.4 ADME Screening
2.10.5 High Throughput Screening: Greatly Increases Efficiency

3. World Cell-Based Assays Market, 2015-2025
3.1 Global Cell-Based Assays Market Forecast 2015-2025
3.2 Drivers for the Cell-Based Assays Market
3.3 Restraints for the Cell-Based Assays Market
3.4 Cell-Based Assays: Market Segments – Products and Services
3.5 Cell-Based Assays, Market Segments: Products Forecast 2015-2025
3.5.1 The Three Main Categories of Cell-Based Assay Products
3.5.1.1 Equipment Needed to Conduct Cell-Based Assays
3.5.1.2 Disposables Necessary to Perform Cell-Based Assays
3.5.1.3 Consumables Forming the Basis of Cell-Based Assays
3.6 Cell-Based Assays Market Segments: Services
3.6.1 Cell-Based Assays Market Segments: Services Forecast 2015-2025
3.7 Cell-Based Assays Market: Applications Forecasts 2015-2025
3.7.1 Drug Discovery Segment
3.7.2 ADME (Absorption, Distribution, Metabolism, Excretion) Segment
3.7.3 Basic Research Segment

4. Leading National Markets for Cell-Based Assays, 2015-2025
4.1 Regional Breakdown of the Global Cell-Based Assays Market, 2014 and 2025
4.2 Global Cell-Based Assays Market: Regional Forecast 2015-2025
4.3 The US Cell-Based Assays Revenue Forecast to 2025
4.4 European Union (EU) Cell-Based Assays Market 2015-2025
4.4.1 IMI’s Pan-European Drug Discovery Platform Holds Much Promise
4.4.2 EU Market: National Breakdown, 2014 and 2025
4.4.3 EU Market: Main National Forecasts 2015-2025
4.4.4 German Cell-Based Assay Revenue Forecast to 2025
4.4.5 French Cell-Based Assays Revenue Forecast to 2025
4.4.6 UK Cell-Based Assays Revenue Forecast to 2025
4.4.7 Spanish Cell-Based Assays Revenue Forecast to 2025
4.4.8 Italian Cell-Based Assays Revenue Forecast to 2025
4.5 Japanese Cell-Based Assays Revenue Forecast to 2025
4.6 BRIC Nations (Brazil, Russia, India, China) Cell-Based Assays Market
4.6.1 BRIC Countries: National Breakdown 2014 and 2015
4.6.2 BRIC Countries: National Forecasts 2015-2025
4.6.3 Chinese Cell-Based Assay Revenue Forecast to 2025
4.6.4 Indian Cell-Based Assays Revenue Forecast to 2025
4.6.5 Russian Cell-Based Assays Revenue Forecast to 2025
4.6.6 Brazilian Cell-Based Assays Revenue Forecast to 2025

5. Companies in the Cell-Based Assays Market: Product Suppliers, 2015
5.1 Thermo Fisher Scientific
5.1.1 Cell-Based Assay Technologies under the Life Technologies Business Unit – Over 300 Products Offered
5.1.2 Also Offers Custom Assays, Related Products and HCA Products
5.2 DiscoveRx
5.2.1 PathHunter Technology
5.2.2 Other Assay Platforms and Drug Discovery Services
5.3 PerkinElmer
5.3.1 AlphaScreen Technology
5.3.2 DELFIA TRF Assays
5.3.3 Label-Free Cellular Assay Detection, and the Opera System
5.4 BD (Becton, Dickinson and Company)
5.4.1 Cell-Based Assays Through BD Life Sciences
5.5 InSphero
5.5.1 GravityPLUS- Leading Solution for 3D Cell-Based Assays
5.6 Biocroi
5.6.1 The Technology Behind and the Advantages of Happy Cell ASM and its 3D Cell Culture
5.7 GE Healthcare
5.7.1 Cell-Based Assays Through GE Healthcare Life Sciences
5.8 Molecular Devices
5.8.1 Cell-Based Assay Products Include SpectraMax Microplate Readers and FLIPR Tetra System
5.9 Promega
5.9.1 Assays Range from Cell Viability Assays to Mitochondrial Function Assays
5.10 BioVision
5.10.1 Cell-Based Assays Include the EZCell Platform and a Cholesterol Detection Kit

6. Companies in the Cell-Based Assays Market: CROs and Service Providers, 2015
6.1 Fluofarma
6.1.1 Over 100 Cell-Based Assays, and Partnership with Harlan
6.2 CYTOO
6.2.1 Cell Micropatterning to Eliminate Trade-Off between Quantity and Quality?
6.2.2 Cell-Based Assays for Muscular Atrophy / Hypertrophy and Anti-Cancer Drug Profiling
6.3 Cell Assay Innovations (CAI)
6.3.1 ClariCELL Technology
6.4 ProQinase
6.4.1 Various Cell-Based Assays for Characterising Anti-Cancer Compounds
6.5 Charles River Laboratories
6.5.1 PhenoFocus – Portfolio of over 100 Primary Cell-Based Assays
6.6 SGS
6.6.1 Offers a Range of Services, Including 3D Cell-Based Assays
6.7 Pharmaceutical Product Development (PPD)
6.8 Marin Biologic Laboratories

7. Cell-Based Assays Technology, Trends and Future Outlook
7.1 Stem Cells: Vast Potential
7.1.1 The Benefits of using Stem Cells in Cell-Based Assays
7.1.2 IPSCs: An Uncontroversial and Abundant Source
7.1.3 Companies Providing Stem Cell-Based Assays
7.2 Toxicity Testing: Important Field for Cell-Based Assays
7.3 3D Systems: The Advantages of these Next Generation Cell Systems
7.3.1 Complexity of 3D Systems is a Challenge, but More and More are Gradually Reaching the Market
7.4 Increasing Outsourcing of Cell-Based Assays
7.5 Label-Free Technology
7.6 GPCRs: A Common Drug and Drug Discovery Target
7.6.1 GPCRs in Cell-Based Assays
7.6.2 Allosteric GPCRs
7.7 Increasing Miniaturisation and Automation
7.7.1 Advantages of Miniaturisation
7.7.2 Advantages of Automation
7.8 Microfluidics- Set to be a Trend
7.8.1 Can Mimic the In Vivo Environment
7.8.2 The Potential and the Challenges
7.9 Multiplexing: Improves Efficiency of Cell-Based Assays
7.9.1 Advantages will Drive Growth
7.10 High Content Screening: A Well Established Tool
7.10.1 The Future for HCS: Will Continue to Expand, Still Room for Innovation
7.11 Cell-Based Assays in Biologics Development

8. Qualitative Analysis of the Cell-Based Assays Market, 2015
8.1 SWOT Analysis of the Cell-Based Assays Market
8.1.1 Strengths Within the Cell-Based Assays Market
8.1.2 Weaknesses Within the Cell-Based Assays Market
8.1.3 Opportunities for the Cell-Based Assays Market
8.1.4 Threats to the Cell-Based Assays Market
8.2 STEP Analysis of the Cell-Based Assays Market
8.2.1 Social Factors
8.2.2 Technological Factors
8.2.3 Economic Factors
8.2.4 Political Factors

9. Research Interviews
9.1 Interview with Luc Selig, Chief Business Officer at CYTOO
9.1.1 CYTOO’s Definition a Cell-Based Assay, and the Cell-Based Assay Market
9.1.2 The Advantages of CYTOO’s Products and Services
9.1.3 Thoughts on the Competition Within the Cell-Based Assays Market
9.1.4 Revenue Expectations, Company Focus and the Future of the Cell-Based Assay Market
9.1.5 On Challenges for the Industry and Cell-Based Assays vs Animal Models
9.2 Interview with Molecular Devices
9.2.1 Molecular Devices’ Definition of the Market
9.2.2 On Molecular Devices’ Most Well-Known Products, and their Advantages
9.2.3 On the Future of the Cell-Based Assays Market
9.2.4 Opportunities and Challenges for the Market, and the Competition Within it
9.3 Interview with Deborah Moshinsky, President and CEO of Cell Assay Innovations (CAI)
9.3.1 On the Challenges of Developing a Cell-Based Assay
9.3.2 On ClariCELL Technology and its Advantages
9.3.3 Competition in the Cell-Based Assays Market and Future Perspectives

10. Conclusions from the Research and Analysis
10.1 Growth Has Been Driven by Advantages of Cell-Based Assays
10.2 Current Status of the Market and its Growth Drivers
10.3 The Most Dominant National Markets and Emerging Countries
10.4 Future Trends and Technology