アルツハイマー病の疫学的予測...市場調査レポートについてご紹介

1 Table of Contents
1 Table of Contents 4
1.1 List of Tables 6
1.2 List of Figures 7

2 Introduction 8
2.1 Related Reports 9
2.2 Upcoming Related Reports 9

3 Epidemiology 10
3.1 Disease Background 10
3.2 Risk Factors and Comorbidities 11
3.2.1 A family history of Alzheimer’s increases the risk of developing the disease by 7.5 times 12
3.2.2 The APOE ε4 allele triples the risk for AD 13
3.2.3 Cardiovascular risk factors in midlife significantly increase the risk of developing AD in later life 13
3.2.4 The incidence and prevalence of AD double every five years after age 65 years 14
3.2.5 Diabetes doubles the risk of AD in men, but only marginally affects the risk in women 14
3.2.6 Women are 1.5 times more likely to develop AD than men 15
3.2.7 Depression triples the risk for AD, and is the most common comorbidity 15
3.2.8 Up to 70% of AD patients also suffer from anxiety 16
3.2.9 Psychosis and agitation are common comorbidities in Alzheimer’s patients 16
3.3 Global Trends 16
3.3.1 US 17
3.3.2 5EU 18
3.3.3 Japan 20
3.3.4 China 21
3.3.5 India 21
3.4 Forecast Methodology 22
3.4.1 Sources Used 27
3.4.2 Forecast Assumptions and Methods 34
3.4.3 Sources Not Used 45
3.5 Epidemiology Forecast (2013-2023) 47
3.5.1 Total Prevalent Cases of AD 47
3.5.2 Age-Specific Total Prevalent Cases of AD 49
3.5.3 Sex-Specific Total Prevalent Cases of AD 51
3.5.4 Age-Standardized Total Prevalence of AD 54
3.5.5 Total Prevalent Cases of AD, by Severity 55
3.5.6 Total Prevalent Cases of MCI 57
3.5.7 Age-Specific Total Prevalent Cases of MCI 59
3.5.8 Sex-Specific Total Prevalent Cases of MCI 61
3.5.9 Age-Standardized Total Prevalence of MCI 63
3.6 Discussion 65
3.6.1 Conclusions Regarding the Epidemiological Trends 65
3.6.2 Limitations of the Analysis 67
3.6.3 Strengths of the Analysis 68

4 Appendix 69
4.1 Bibliography 69
4.2 About the Authors 77
4.2.1 Epidemiologist 77
4.2.2 Reviewers 77
4.2.3 Global Director of Therapy Analysis and Epidemiology 78
4.2.4 Global Head of Healthcare 79
4.3 About GlobalData 80
4.4 About EpiCast 80
4.5 Disclaimer 81