【レポートの概要(一部)】
Table of Contents
Table of Contents 2
List of Tables 6
List of Figures 7
Introduction 8
Global Markets Direct Report Coverage 8
Atrial Fibrillation Overview 9
Therapeutics Development 10
Pipeline Products for Atrial Fibrillation – Overview 10
Pipeline Products for Atrial Fibrillation – Comparative Analysis 11
Atrial Fibrillation – Therapeutics under Development by Companies 12
Atrial Fibrillation – Pipeline Products Glance 14
Late Stage Products 14
Clinical Stage Products 15
Early Stage Products 16
Atrial Fibrillation – Products under Development by Companies 17
Atrial Fibrillation – Companies Involved in Therapeutics Development 19
ARCA biopharma, Inc. 19
Armetheon, Inc. 20
AstraZeneca PLC 21
Bristol-Myers Squibb Company 22
Cardiome Pharma Corp 23
Daiichi Sankyo Company, Limited 24
Gilead Sciences, Inc. 25
Isis Pharmaceuticals, Inc. 26
Laboratoires Pierre Fabre SA 27
Nissan Chemical Industries, Ltd. 28
Nyken BV 29
Otsuka Holdings Co., Ltd. 30
Regado Biosciences, Inc. 31
Serodus ASA 32
Xention Limited 33
Atrial Fibrillation – Therapeutics Assessment 34
Assessment by Monotherapy Products 34
Assessment by Combination Products 35
Assessment by Target 36
Assessment by Mechanism of Action 38
Assessment by Route of Administration 40
Assessment by Molecule Type 42
Drug Profiles 44
(ranolazine + dronedarone) – Drug Profile 44
Product Description 44
Mechanism of Action 44
R&D Progress 44
Aptamers for Cardiovascular Diseases – Drug Profile 46
Product Description 46
Mechanism of Action 46
R&D Progress 46
BMS-919373 – Drug Profile 47
Product Description 47
Mechanism of Action 47
R&D Progress 47
bucindolol hydrochloride – Drug Profile 48
Product Description 48
Mechanism of Action 48
R&D Progress 48
budiodarone – Drug Profile 50
Product Description 50
Mechanism of Action 50
R&D Progress 50
Drug For Atrial Fibrillation – Drug Profile 52
Product Description 52
Mechanism of Action 52
R&D Progress 52
edoxaban tosylate – Drug Profile 53
Product Description 53
Mechanism of Action 53
R&D Progress 53
F-373280 – Drug Profile 55
Product Description 55
Mechanism of Action 55
R&D Progress 55
GsMTx-4 – Drug Profile 56
Product Description 56
Mechanism of Action 56
R&D Progress 56
ISIS-CRPRx – Drug Profile 58
Product Description 58
Mechanism of Action 58
R&D Progress 58
NIP-151 – Drug Profile 59
Product Description 59
Mechanism of Action 59
R&D Progress 59
NYK-1112 – Drug Profile 61
Product Description 61
Mechanism of Action 61
R&D Progress 61
OMT-33 – Drug Profile 62
Product Description 62
Mechanism of Action 62
R&D Progress 62
OPC-108459 – Drug Profile 63
Product Description 63
Mechanism of Action 63
R&D Progress 63
ranolazine ER – Drug Profile 64
Product Description 64
Mechanism of Action 64
R&D Progress 64
SER-102 – Drug Profile 66
Product Description 66
Mechanism of Action 66
R&D Progress 66
Small Molecule to Block IKACh for Atrial Fibrillation – Drug Profile 67
Product Description 67
Mechanism of Action 67
R&D Progress 67
Small Molecule to Block Kv1.5 for Atrial Fibrillation – Drug Profile 68
Product Description 68
Mechanism of Action 68
R&D Progress 68
Small Molecules to Activate Heat Shock Protein 70 (Hsp70) for Post-Operative Atrial Fibrillation – Drug Profile 69
Product Description 69
Mechanism of Action 69
R&D Progress 69
Small Molecules to Block Voltage Gated Sodium Channel for Atrial Fibrillation – Drug Profile 70
Product Description 70
Mechanism of Action 70
R&D Progress 70
vanoxerine – Drug Profile 72
Product Description 72
Mechanism of Action 72
R&D Progress 72
vernakalant hydrochloride – Drug Profile 73
Product Description 73
Mechanism of Action 73
R&D Progress 73
XEN-D0101 – Drug Profile 75
Product Description 75
Mechanism of Action 75
R&D Progress 75
XEN-D0103 – Drug Profile 76
Product Description 76
Mechanism of Action 76
R&D Progress 76
XEN-R0702 – Drug Profile 77
Product Description 77
Mechanism of Action 77
R&D Progress 77
Atrial Fibrillation – Recent Pipeline Updates 78
Atrial Fibrillation – Dormant Projects 90
Atrial Fibrillation – Discontinued Products 94
Atrial Fibrillation – Product Development Milestones 95
Featured News & Press Releases 95
Dec 08, 2014: Daiichi Sankyo Launches New Formulation of LIXIANA 60 mg Tablets (edoxaban) in Japan 95
Nov 07, 2014: Cardiome Announces Positive Results from the BRINAVESS Asia-Pacific Phase 3 Clinical Trial 95
Nov 07, 2014: Cardiome Submits BRINAVESS Reimbursement Dossier to Italian Authorities to Support Market Access 96
Oct 31, 2014: U.S. FDA Cardiovascular and Renal Drugs Advisory Committee Makes Recommendation on Daiichi Sankyo’s Once-Daily SAVAYSA™ (edoxaban) for the Reduction in Risk of Stroke and Systemic Embolic Events in Patients with Non-Valvular Atrial Fibrillation 96
Oct 28, 2014: U.S. FDA Cardiovascular and Renal Drugs Advisory Committee Makes Recommendation on Daiichi Sankyo’s Once-Daily SAVAYSA for the Reduction in Risk of Stroke and Systemic Embolic Events in Patients with Non-Valvular Atrial Fibrillation 97
Sep 26, 2014: Daiichi Sankyo Receives Approval for Additional Indications of LIXIANA (edoxaban) in Japan 98
Sep 02, 2014: Subgroup Analysis of ENGAGE AF-TIMI 48 Explores the Relationship Between Edoxaban Dose, Concentration, Anti-Factor Xa Activity and Outcomes 98
Sep 01, 2014: Xention commences first phase 2 study of XEN-D0103 in atrial fibrillation 100
Aug 25, 2014: Cardiome Enters Commercialization Agreement With Eurolab Especialidades Medicinales For BRINAVESS In Argentina 101
Aug 06, 2014: Cardiome Submits Brinavess Dossier To French Authorities To Support Market Access 101
Appendix 102
Methodology 102
Coverage 102
Secondary Research 102
Primary Research 102
Expert Panel Validation 102
Contact Us 103
Disclaimer 103
【レポート販売概要】
■ タイトル:心房細動(Atrial Fibrillation)の治療薬パイプライン動向(2015年上半期版)■ 英文:Atrial Fibrillation - Pipeline Review, H1 2015
■ 発行日:2015年1月22日
■ 調査会社:Global Markets Direct
■ 商品コード:GMDHC6040IDB
■ 調査対象地域:グローバル
- 高級香水の世界市場:価格別(50〜100ドル、100〜200ドル、200ドル以上)、エンドユーザー別(男性、女性、ユニセックス)、流通経路別(専門店、オンラインストア)The luxury perfume market size was valued at $11.7 Bn in 2018 and is expected to reach $16.8 Bn by 2026, registering a CAGR of 5.3% from 2019 to 2026. Lifestyle consciousness and increased buying power of customers are major impacts of increased disposable income, which naturally leads to a growth in usage of products and services. Increase in employment rate is impels rapid growth of disposable i …
- 世界のフローサイトメトリー(医療機器)市場:サプライヤーシェア及び市場予測Complete report $18,500. DataPack (test volumes, sales forecasts, supplier shares) $7,400.This 7-country report will help current suppliers and potential market entrants identify and evaluate emerging opportunities in the flow cytometry markets during the next five years. The report explores future marketing and technological trends in seven countries; provides market share estimates, …
- ホームセキュリティシステムの世界市場:セキュリティカメラ、電子/スマートロック、センサー、感知器、アラーム、セキュリティソリューション、DIYホームセキュリティThe rising incidents of security concerns has led to increased safety measures by residential dwellings. As a result, the global home security system market is projected to grow at a remarkable rate of above 13% during the forecast period. Advancement in technology and emergence of smart homes has led to the rise of integrated home security systems, which can be connected to smartphones and enable …
- サプライチェーン分析の世界市場分析:ソリューション別(企画調達、製造、販売&運営、物流分析、ビジュアライゼーション・レポート)、展開別、エンドユーザー別、地域別、セグメント予測、2014-2025The global supply chain analytics market is expected to reach USD 9.87 billion by 2025, according to a new study by Grand View Research, Inc. The growing need to manage a large amount of business data and use derived insights is optimizing the demand for supply chains. The increasing awareness among consumers regarding the benefits offered by supply chain analytics has encouraged organizations acr …
- 硫酸の世界市場動向及び予測2015The present report is an essential resource for a one looking for detailed information on the world sulfuric acid market. The report covers data on global, regional and national markets including present and future trends for supply and demand, prices, and downstream industries. In addition to the analytical part, the report provides a range of tables and figures which all together give a true ins …
- 世界の光ファイバセンサ市場2015The Global Fiber Optic Sensors Industry 2015 Market Research Report is a professional and in-depth study on the current state of the Fiber Optic Sensors industry. The report provides a basic overview of the industry including definitions, classifications, applications and industry chain structure.The Fiber Optic Sensors market analysis is provided for the international markets including developmen …
- ビル自動化・制御システムの世界市場2017-2021About Building Automation and Control Systems Building automation and control systems are solutions installed in buildings to increase the operational efficiency and to reduce the overall energy consumption. It provides automatic centralized control and monitoring of the building lighting systems, HVAC, and safety and access systems among others. It develops software for an efficient building mana …
- 世界の水素ガス市場動向(2012-2016)TechNavio's analysts forecast the Global Hydrogen Gas market to grow at a CAGR of 6.84 percent over the period 2012-2016. One of the key factors contributing to this market growth is the need for cleaner fuel. The Global Hydrogen Gas market has also been witnessing steady adoption toward steam reforming. However, the need for increased investment could pose a challenge to the growth of this market …
- 医療、制度、医療費償還現状:インド市場CountryFocus: Healthcare, Regulatory and Reimbursement Landscape - India Summary GlobalData, the industry analysis specialist, has released its latest report, "CountryFocus: Healthcare, Regulatory and Reimbursement Landscape - India". The report is an essential source of information on and analysis of the healthcare, regulatory and reimbursement landscape in India. It identifies the key trends in …
- カーボンナノチューブの世界市場:MWCNT、SWCNTAbout Carbon Nanotubes Carbon nanotubes are cylinder-shaped graphite sheets. They may consist of a single layer (SWCNTs) or many layers (MWCNTs). They have high thermal and electrical conductivity and are utilized in a wide variety of applications. Some high growth applications of carbon nanotubes are in electronic devices, electrochemical sensors and biosensors, transistors, lithium-ion (li-ion) …
- ヒューマンマシンインターフェース(HMI)の世界市場2016-2020About Human Machine Interface (HMI) HMI is a tool that helps machines and humans communicate. HMI systems are widely adopted for plant automation; they help operators interact with automation systems and understand the plant floor automation process. This system helps feed inputs, and monitors, controls, and checks the parameters connected to the control system. It enhances operational efficiency, …
- Fetzima (大うつ病性障害):医薬品市場予測及び分析(~2023)Fetzima (Major Depressive Disorder) - Forecast and Market Analysis to 2023 Summary Major depressive disorder (MDD) is one of the most common psychiatric diseases worldwide. The MDD market is a crowded and competitive market, with more than 30 marketed products available for the treatment of patients with MDD. The depression market is about to enter a dynamic phase with imminent patent expiries for …
- 伸縮性シュリンクフィルムの世界市場分析:樹脂別(リニア低密度ポリエチレン(LLDPE)、低密度ポリエチレン(LDPE)、ポリ塩化ビニル(PVC))副産物(フード、スリーブ、ラベル、ラップ))、用途別(食品・飲料、工業用包装、医薬品、消費財)、セグメント予測、2014 – 2025The global stretch and shrink film market is expected to reach USD 18.46 billion by 2024, according to a new report by Grand View Research, Inc. Rising demand for the light-weight material for industrial packaging is expected to drive growth for the product over the forecast period. The demand is expected to be driven by superior packaging properties such as improved printability, easier applicati …
- Peyto Exploration & Development Corp.:石油・ガスの開発・生産動向及びコスト分析- Q2, 2013Peyto Exploration & Development Corp. Oil & Gas Exploration and Production Operations and Cost Analysis - Q2, 2013 Summary Peyto Exploration & Development Corp. Oil & Gas Exploration and Production Operations and Cost Analysis is the latest report from GlobalData, the industry analysis specialists, that offers comprehensive information on the operational and financial performance of the company. T …
- スモールデザインのタブレット端末:Small Form Factor TabletsThe Mobile Index provides a sophisticated, proprietary algorithm for scoring the top products and services in each of 60+ mobile and wireless categories based on four variables: 1) technology innovation, 2) management strength, 3) market acceptance and 4) financial strength. The Mobile Index service gives enterprises more information than other rating services since it considers four important var …