【レポートの概要（一部）】
Table of Contents
Table of Contents 2
List of Tables 6
List of Figures 7
Introduction 8
Global Markets Direct Report Coverage 8
Acute Renal Failure (ARF) (Acute Kidney Injury) Overview 9
Therapeutics Development 10
Pipeline Products for Acute Renal Failure (ARF) (Acute Kidney Injury) – Overview 10
Pipeline Products for Acute Renal Failure (ARF) (Acute Kidney Injury) – Comparative Analysis 11
Acute Renal Failure (ARF) (Acute Kidney Injury) – Therapeutics under Development by Companies 12
Acute Renal Failure (ARF) (Acute Kidney Injury) – Therapeutics under Investigation by Universities/Institutes 15
Acute Renal Failure (ARF) (Acute Kidney Injury) – Pipeline Products Glance 16
Clinical Stage Products 16
Early Stage Products 17
Unknown Stage Products 18
Acute Renal Failure (ARF) (Acute Kidney Injury) – Products under Development by Companies 19
Acute Renal Failure (ARF) (Acute Kidney Injury) – Products under Investigation by Universities/Institutes 21
Acute Renal Failure (ARF) (Acute Kidney Injury) – Companies Involved in Therapeutics Development 22
ACROVIS biostructures GmbH 22
Adrenomed AG 23
Am-Pharma B.V. 24
Angion Biomedica Corp. 25
Bolder Biotechnology, Inc. 26
Cellmid Limited 27
DiaMedica Inc. 28
Digna Biotech, S.L. 29
F. Hoffmann-La Roche Ltd. 30
G1 Therapeutics, Inc. 31
Hadasit Medical Research Services & Development Ltd 32
Kringle Pharma, Inc. 33
NephroGenex, Inc. 34
Noorik Biopharmaceuticals AG 35
Nyken BV 36
Opsona Therapeutics Ltd. 37
Quark Pharmaceuticals, Inc. 38
STATegics, Inc. 39
Thrasos, Inc. 40
Torrent Pharmaceuticals Limited 41
Acute Renal Failure (ARF) (Acute Kidney Injury) – Therapeutics Assessment 42
Assessment by Monotherapy Products 42
Assessment by Target 43
Assessment by Mechanism of Action 45
Assessment by Route of Administration 47
Assessment by Molecule Type 49
Drug Profiles 51
adrecizumab – Drug Profile 51
Product Description 51
Mechanism of Action 51
R&D Progress 51
BB-3 – Drug Profile 52
Product Description 52
Mechanism of Action 52
R&D Progress 52
BBT-030 – Drug Profile 54
Product Description 54
Mechanism of Action 54
R&D Progress 54
BBT-045 – Drug Profile 55
Product Description 55
Mechanism of Action 55
R&D Progress 55
CAB-101 – Drug Profile 56
Product Description 56
Mechanism of Action 56
R&D Progress 56
cardiotrophin-1 – Drug Profile 58
Product Description 58
Mechanism of Action 58
R&D Progress 58
Cell Therapy to Activate Wnt7b for Kidney Injury – Drug Profile 60
Product Description 60
Mechanism of Action 60
R&D Progress 60
CXA-10 – Drug Profile 61
Product Description 61
Mechanism of Action 61
R&D Progress 61
DM-199 – Drug Profile 62
Product Description 62
Mechanism of Action 62
R&D Progress 62
HYPER-IL-6 – Drug Profile 64
Product Description 64
Mechanism of Action 64
R&D Progress 64
KP-100IT – Drug Profile 65
Product Description 65
Mechanism of Action 65
R&D Progress 65
MTP-131 – Drug Profile 67
Product Description 67
Mechanism of Action 67
R&D Progress 67
N-003 – Drug Profile 69
Product Description 69
Mechanism of Action 69
R&D Progress 69
NOXD-21 – Drug Profile 70
Product Description 70
Mechanism of Action 70
R&D Progress 70
NYK-1341 – Drug Profile 71
Product Description 71
Mechanism of Action 71
R&D Progress 71
OPN-305 – Drug Profile 72
Product Description 72
Mechanism of Action 72
R&D Progress 72
Pyridoxamine Dihydrochloride – Drug Profile 74
Product Description 74
Mechanism of Action 74
R&D Progress 74
QPI-1002 – Drug Profile 76
Product Description 76
Mechanism of Action 76
R&D Progress 76
R-190 – Drug Profile 78
Product Description 78
Mechanism of Action 78
R&D Progress 78
Recombinant Human Alkaline Phosphatase – Drug Profile 80
Product Description 80
Mechanism of Action 80
R&D Progress 80
RO-6839328 – Drug Profile 82
Product Description 82
Mechanism of Action 82
R&D Progress 82
Small Molecule to Activate Heat Shock Protein 70 (Hsp70) for Delayed Graft Function – Drug Profile 83
Product Description 83
Mechanism of Action 83
R&D Progress 83
Small Molecule to Inhibit CDK4 and CDK6 for Acute Kidney Injury and Breast Cancer – Drug Profile 84
Product Description 84
Mechanism of Action 84
R&D Progress 84
Small Molecule to Inhibit HDAC for Acute Kidney Injury – Drug Profile 85
Product Description 85
Mechanism of Action 85
R&D Progress 85
Small Molecules for Acute Renal Failure – Drug Profile 86
Product Description 86
Mechanism of Action 86
R&D Progress 86
STSE-15 – Drug Profile 87
Product Description 87
Mechanism of Action 87
R&D Progress 87
THR-184 – Drug Profile 88
Product Description 88
Mechanism of Action 88
R&D Progress 88
TRC-160334 – Drug Profile 89
Product Description 89
Mechanism of Action 89
R&D Progress 89
Acute Renal Failure (ARF) (Acute Kidney Injury) – Recent Pipeline Updates 90
Acute Renal Failure (ARF) (Acute Kidney Injury) – Dormant Projects 102
Acute Renal Failure (ARF) (Acute Kidney Injury) – Discontinued Products 103
Acute Renal Failure (ARF) (Acute Kidney Injury) – Product Development Milestones 104
Featured News & Press Releases 104
Dec 15, 2014: Complexa Initiates Phase 1B Study of CXA-10 in Acute Kidney Injury 104
Nov 13, 2014: AM-Pharma Presents Preclinical Data On Mode-Of-Action For RecAP In Acute Kidney Injury 104
Sep 16, 2014: Thrasos Announces Successful Formal Interim Analysis and Clinical Update for Phase 2 Study of THR-184 for Acute Kidney Injury 105
Jul 01, 2014: Quark Announces Completion of Phase II Trial Evaluating QPI-1002 for Prevention of Delayed Graft Function in Kidney Transplant Patients 106
May 01, 2014: Complexa Initiates First Clinical Trial of CXA-10 for Acute Kidney Injury 106
Mar 26, 2014: AM-Pharma announces positive Phase I data on recAP for Acute Kidney Injury 107
Feb 04, 2014: FDA Grants Thrasos Fast Track Designation for THR-184 in Acute Kidney Injury 107
Jan 28, 2014: American Journal of Kidney Disease publishes review article of Alkaline Phosphatase 108
Nov 08, 2013: AM-Pharma Presents Positive Data from recAP Preclinical Study at ASN Meeting 108
Sep 23, 2013: AM-Pharma Returns to Clinic with Phase I Trial of New Recombinant Human Alkaline Phosphatase to Treat Acute Kidney Injury 109
Appendix 110
Methodology 110
Coverage 110
Secondary Research 110
Primary Research 110
Expert Panel Validation 110
Contact Us 111
Disclaimer 111
【レポート販売概要】
■ タイトル：急性腎不全(急性腎傷害)(Acute Renal Failure)の治療薬パイプライン動向（2015年上半期版）■ 英文：Acute Renal Failure (ARF) (Acute Kidney Injury) - Pipeline Review, H1 2015
■ 発行日：2015年1月22日
■ 調査会社：Global Markets Direct
■ 商品コード：GMDHC6037IDB
■ 調査対象地域：グローバル
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