痛風(Gout)治療市場:市場機会分析と予測(~2018)...市場調査レポートについてご紹介

【英文タイトル】OpportunityAnalyzer: Gout - Opportunity Analysis and Forecast to 2018

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痛風(Gout)治療市場:市場機会分析と予測(~2018) (Code:GDHC020POA)

【レポートの概要(一部)】

OpportunityAnalyzer: Gout – Opportunity Analysis and Forecast to 2018

Summary

GlobalData estimates the 2013 sales for gout at approximately $989m across the 6MM covered in this report. The acute gout segment of the market will double in size over the forecast period, reaching $337m in 2018 at a CAGR of 15%. The chronic gout market, which encompasses urate-lowering and prophylactic anti-inflammatory therapies, will experience even faster growth at a CAGR of 18.8%, and it will more than double in size, reaching over 1.9 billion in 2018. With the current standard of care for gout already encompassing very successful and cheap treatments, the bar for success in the gout market is quite high. As a result, companies are shifting the focus of their research toward more severe gout cases, trying to address the greatest unmet needs. One of the major drivers of the gout market is the growing number of patients suffering from difficult-to-treat gout, for whom the standard therapies are inappropriate due to the presence of comorbidities, unresponsiveness, or intolerance. Targeting this patient niche is the strongest trend in the research and development (R&D) strategies of the gout players.

Highlights

Key Questions Answered

– Although the standard treatments are cheap and effective in most gout patients, there are a growing number of patients for whom the standard therapies are inappropriate. Gout market is still marked by the presence of a number of unmet needs in current treatments. What are the main unmet needs in this market? Will the drugs under development fulfil the unmet needs of the gout market?
– The late-stage gout pipeline is sparsely populated; however these drugs in development will be a strong driver of the gout market growth. Which of these drugs will attain high sales revenues during 2013-2018? Which of these drugs will have the highest peak sales at the highest CAGR, and why?
– The more aggressive approach to urate-lowering treatment will increase the patient pool treated with urate-lowering agents and prophylactic anti-inflammatory therapies. How will these changes impact the growth of the future market?

Key Findings

– One of the main drivers of the enormous expansion of the gout market will be the introduction of the novel urate-lowering agents, lesinurad and ulodesine, which will be used as add-on therapies to the current standard of care and target the treatment-failure gout population.
– Another strong driver will be the more aggressive approach to urate-lowering treatment, as recommended by the latest treatment guidelines, which will increase the patient pool treated with urate-lowering agents and prophylactic anti-inflammatory therapy.
– Companies are shifting the focus of their research toward more severe gout cases, trying to address the greatest unmet needs.
– Reasons for inadequate gout treatment include a poor patient understanding of their disease and physician failure to develop targeted treatment plans.

Scope

– Overview of gout, including epidemiology, etiology, pathophysiology, symptoms, diagnosis, and treatment guidelines.
– Annualized gout therapeutics market revenue, annual cost of therapy and treatment usage pattern data from 2013 and forecast for five years to 2018.
– Key topics covered include strategic competitor assessment, market characterization, unmet needs, clinical trial mapping and implications for the gout therapeutics market.
– Pipeline analysis: comprehensive data split across different phases, emerging novel trends under development, and detailed analysis of late-stage pipeline drugs.
– Analysis of the current and future market competition in the global gout therapeutics market. Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to buy

– Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline. Additionally a list of acquisition targets included in the pipeline product company list.
– Develop business strategies by understanding the trends shaping and driving the gout therapeutics market.
– Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the gout therapeutics market in future.
– Formulate effective sales and marketing strategies by understanding the competitive landscape and by analysing the performance of various competitors.
– Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
.....


【日本語概要(※自動翻訳出力)】

※以下は、Microsoft社の翻訳システムを使用した自動翻訳結果です。レイアウト崩れと不自然な日本語表現が多く表示されます。

。。。(後略)

【レポートの目次(一部)】

1 Table of Contents
1 Table of Contents 9
1.1 List of Tables 13
1.2 List of Figures 15
2 Introduction 16
2.1 Catalyst 16
2.2 Related Reports 17
2.3 Upcoming Related Reports 17
3 Disease Overview 18
3.1 Etiology and Pathophysiology 19
3.1.1 Etiology 19
3.1.2 Pathophysiology 21
3.2 Symptoms 22
3.3 Risk Factors 23
3.4 Prognosis 23
3.5 Quality of Life 24
4 Epidemiology 25
4.1 Risk Factors and Comorbidities 25
4.2 Global Trends 27
4.2.1 US 29
4.2.2 5EU 29
4.3 Forecast Methodology 30
4.3.1 Sources Used 34
4.3.2 Sources Not Used 38
4.3.3 Forecast Assumptions and Methods 40
4.4 Epidemiological Forecast for Gout (2013-2023) 47
4.4.1 Diagnosed Incidence 47
4.4.2 Diagnosed Prevalence 53
4.5 Discussion 61
4.5.1 Epidemiological Forecast Insight 61
4.5.2 Limitations of the Analysis 62
4.5.3 Strengths of the Analysis 63
5 Current Treatment Options 64
5.1 Overview 64
5.2 Product Profiles 67
5.2.1 Anti-Inflammatory Therapies 67
5.2.2 Urate-Lowering Therapies 86
6 Unmet Needs Assessment and Oppportunity Analysis 103
6.1 Overview 103
6.2 Physician and Patient Awareness of Gout 104
6.2.1 Unmet Needs 104
6.2.2 Gap Analysis 105
6.2.3 Opportunity 106
6.3 Noncompliance to Gout Therapies 106
6.3.1 Unmet Needs 106
6.3.2 Gap Analysis 107
6.3.3 Opportunity 107
6.4 Earlier and More Accurate Diagnosis of Gout 107
6.4.1 Unmet Needs 107
6.4.2 Gap Analysis and Opportunity 108
6.4.3 Opportunity 109
6.5 Efficacious and Safe Treatment of Difficult-to-Treat Gout 109
6.5.1 Unmet Needs 109
6.5.2 Gap Analysis and Opportunity 109
6.5.3 Opportunity 110
7 Research and Development Strategies 111
7.1 Overview 111
7.1.1 Targeting Patients with Refractory Gout – Novel Uricosuric Drugs as Add-On Therapy 111
7.1.2 Targeting Patients with Refractory Gout – PEGylation of Uricase 112
7.1.3 Small Molecules as Inhibitors of the Interleukin-1 Beta Pathway 113
7.1.4 Acquisitions and Licensing 113
7.2 Clinical Trial Design 115
7.2.1 Current Clinical Trial Design 115
7.2.2 Future Clinical Trial Designs 120
8 Pipeline Assessment 122
8.1 Overview 122
8.2 Promising Drugs in Clinical Development 124
8.2.1 Lesinurad (RDEA-594) 125
8.2.2 Ulodesine (BCX4208) 130
8.3 Innovative Early-Stage Approaches 134
9 Pipeline Valuation Analysis 138
9.1 Clinical Benchmark of Key Pipeline Drugs 138
9.2 Commercial Benchmark of Key Pipeline Drugs 140
9.3 Competitive Assessment 141
9.4 Top-Line Five-Year Forecast 144
9.4.1 US 147
9.4.2 5EU 148
10 Appendix 150
10.1 Bibliography 150
10.2 Abbreviations 164
10.3 Methodology 168
10.4 Forecasting Methodology 168
10.4.1 Diagnosed Gout Patients 168
10.4.2 Percent Drug-Treated Patients 169
10.4.3 Drugs Included in Each Therapeutic Class 169
10.4.4 Launch and Patent Expiry Dates 169
10.4.5 General Pricing Assumptions 170
10.4.6 Individual Drug Assumptions 171
10.4.7 Pricing of Pipeline Agents 175
10.5 Physicians and Specialists Included in this Study 176
10.6 About the Authors 178
10.6.1 Analyst 178
10.6.2 Therapy Director – CVMD and Infectious Disease 178
10.6.3 Epidemiologist 179
10.6.4 Global Head of Healthcare 179
10.7 About GlobalData 180
10.8 Disclaimer 180

.....

【日本語目次(※自動翻訳出力)】

※以下は、Microsoft社の翻訳システムを使用した自動翻訳結果です。レイアウト崩れと不自然な日本語表現が多く表示されます。

。。。(後略)

【レポート販売概要】

■ タイトル:痛風(Gout)治療市場:市場機会分析と予測(~2018)
■ 英文:OpportunityAnalyzer: Gout - Opportunity Analysis and Forecast to 2018
■ 発行日:2014年4月30日
■ 調査会社:GlobalData
■ 商品コード:GDHC020POA
■ 調査対象地域:グローバル

▼当市場調査レポートの詳細内容確認、お問い合わせ及びご購入申込は下記ページでお願いします。▼
痛風(Gout)治療市場:市場機会分析と予測(~2018) (OpportunityAnalyzer: Gout - Opportunity Analysis and Forecast to 2018 / GDHC020POA)

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