アルツハイマー病治療薬の世界市場予測および分析...市場調査レポートについてご紹介

【英文タイトル】PharmaPoint: Alzheimer’s Disease - Global Drug Forecast and Market Analysis to 2023 - Event-Driven Update

▼当市場調査レポートの詳細内容確認、お問い合わせ及びご購入申込は下記ページでお願いします。▼
アルツハイマー病治療薬の世界市場予測および分析 (Code:GDHC010EPIDR)

【レポートの概要(一部)】

PharmaPoint: Alzheimer’s Disease – Global Drug Forecast and Market Analysis to 2023 – Event-Driven Update

Summary

Alzheimer’s Disease (AD) is a progressive neurodegenerative disease that is characterized by memory loss, cognitive impairment, and functional decline. During the early stages of disease, sleep disturbances and forgetfulness are generally the first presenting symptoms. In the severe stages, patients with AD require permanent observation either by a home care professional or family member. The rapidly declining status of patients with AD results in a drastic reduction in quality of life (QOL), both for the patients and their caretakers. With rapidly accelerating worldwide prevalence, AD has been identified as a major global health threat by the international medical community. Significant efforts have been made to develop a new treatment for AD, as current pharmacologic management is known to only provide temporary improvement of symptoms. Without therapies that effectively stop or reverse the course of the disease, a large area opportunity exists for the development of an effective pharmacologic approach.

Highlights

Key Questions Answered

– What are the preferred therapies for each country?
– The developmental pipeline consists of disease-modifying therapies (DMTs) that aim to prevent the disease in early- and presymptomatic patients. Which of these DMTs will attain high sales revenues during 2013-2023, and in which markets?
– Will amyloid-based therapies face adoption challenges in the market? What is the projected uptake of new passive immunotherapies and BACE inhibitors over the forecast period?
– How large an impact will Lundbeck’s LuAE-58054 and Forum/Mitsubishi Tanabe’s EVP-6124 have on the schizophrenia market? What do key opinion leaders think of these treatment approaches?
– What are the unique challenges in AD, and how will they affect the growth of the market globally?

Key Findings

– Guidelines are not closely followed due to the heterogeneity of symptoms.
– There is a widespread reluctance to seek treatment in the absence of curative therapies.
– Diagnosis in early stages of the disease remains a challenge and will affect the growth of the market over the 2013-2023 forecast period.
– Poor consensus over clinical trial endpoints required for approval.
– Symptoms related to AD require better treatment options.
– Amyloid beta is the focus of the late-stage pipeline.
– Disease-modifying therapies such as passive immunotherapies and BACE inhibitors will revitalize the AD market.

Scope

– Overview of AD and mild cognitive impairment (MCI), including etiology, general symptoms, country-specific compliance/caregiving data and epidemiology.
– Annualized AD market revenue, annual cost of treatment and usage patterns from 2013 and forecast for ten years to 2023.
– Key topics covered include strategic competitor assessment, unmet needs, clinical trial mapping and implications for the AD market.
– Pipeline analysis: comprehensive data split across AD disease severities for disease-modifying and symptomatic therapies with novel mechanisms of action in AD, including Lilly’s solanezumab, Biogen’s aducanumab, Roche’s gantenerumab and crenezumab (Phase II). Merck & Co.’s M-8931, and Lilly/AstraZeneca’s AZD-3293.
– Analysis of the current and future market competition in the global AD drug market. Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to buy

– Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most competitive pipelines.
– Develop business strategies by understanding the trends shaping and driving the AD market.
– Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global AD market in the future.
– Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
– Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
– Track drug sales in the global AD market from 2013-2023.
– Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.

.....

【日本語概要(※自動翻訳出力)】

※以下は、Microsoft社の翻訳システムを使用した自動翻訳結果です。レイアウト崩れと不自然な日本語表現が多く表示されます。

。。。(後略)

【レポートの目次(一部)】

1 Table of Contents
1 Table of Contents 8
1.1 List of Tables 15
1.2 List of Figures 21
2 Introduction 24
2.1 Catalyst 24
2.2 Related Reports 25
2.3 Upcoming Related Reports 25
3 Disease Overview 26
3.1 Etiology and Pathophysiology 26
3.1.1 Etiology 27
3.1.2 Pathophysiology 29
3.2 Disease Staging Systems 38
3.3 Symptoms 41
3.4 Prognosis 43
3.5 Quality of Life 43
4 Epidemiology 45
4.1 Disease Background 45
4.2 Risk Factors and Comorbidities 46
4.2.1 A family history of Alzheimer’s increases the risk of developing the disease by 7.5 times 47
4.2.2 The APOE ε4 allele triples the risk for AD 48
4.2.3 Cardiovascular risk factors in midlife significantly increase the risk of developing AD in later life 48
4.2.4 The incidence and prevalence of AD double every five years after age 65 years 49
4.2.5 Diabetes doubles the risk of AD in men, but only marginally affects the risk in women 49
4.2.6 Women are 1.5 times more likely to develop AD than men 50
4.2.7 Depression triples the risk for AD, and is the most common comorbidity 50
4.2.8 Up to 70% of AD patients also suffer from anxiety 51
4.2.9 Psychosis and agitation are common comorbidities in Alzheimer’s patients 51
4.3 Global Trends 51
4.3.1 US 52
4.3.2 5EU 53
4.3.3 Japan 55
4.3.4 China 56
4.3.5 India 56
4.4 Forecast Methodology 57
4.4.1 Sources Used 62
4.4.2 Forecast Assumptions and Methods 69
4.4.3 Sources Not Used 79
4.5 Epidemiology Forecast (2013-2023) 81
4.5.1 Total Prevalent Cases of AD 81
4.5.2 Age-Specific Total Prevalent Cases of AD 83
4.5.3 Sex-Specific Total Prevalent Cases of AD 85
4.5.4 Age-Standardized Total Prevalence of AD 88
4.5.5 Total Prevalent Cases of AD, by Severity 89
4.5.6 Total Prevalent Cases of MCI 91
4.5.7 Age-Specific Total Prevalent Cases of MCI 93
4.5.8 Sex-Specific Total Prevalent Cases of MCI 95
4.5.9 Age-Standardized Total Prevalence of MCI 98
4.6 Discussion 99
4.6.1 Conclusions Regarding the Epidemiological Trends 99
4.6.2 Limitations of the Analysis 101
4.6.3 Strengths of the Analysis 102
5 Disease Management 103
5.1 Diagnosis Overview 103
5.1.1 Probable AD Dementia 106
5.1.2 Preclinical AD 107
5.1.3 MCI 108
5.2 Treatment Overview 110
5.3 Clinical Practice 112
5.3.1 Leading Prescribed Therapies 114
5.4 US 115
5.5 France 118
5.6 Germany 120
5.7 Italy 122
5.8 Spain 124
5.9 UK 126
5.10 Japan 129
5.11 China 131
5.12 India 133
6 Competitive Assessment 135
6.1 Overview 135
6.2 Product Profiles – Major Brands 136
6.2.1 Aricept (donepezil hydrochloride) 136
6.2.2 Exelon (rivastigmine, rivastigmine tartrate) 141
6.2.3 Razadyne (galantamine hydrobromide) 146
6.2.4 Namenda (memantine hydrochloride) 151
6.3 Other Drugs/Classes 157
7 Unmet Need and Opportunity 159
7.1 Overview 159
7.2 Drugs with Disease-Modifying Mechanisms of Action 160
7.2.1 Unmet Need 160
7.2.2 Gap Analysis 161
7.2.3 Opportunity 162
7.3 Diagnosis in the Prodromal or Presymptomatic Stages 163
7.3.1 Unmet Need 163
7.3.2 Gap Analysis 164
7.3.3 Opportunity 165
7.4 Improved Control of Symptoms 166
7.4.1 Unmet Need 166
7.4.2 Gap Analysis 167
7.4.3 Opportunity 168
7.5 Easier Access to Treatment 169
7.5.1 Unmet Need 169
7.5.2 Gap Analysis 169
7.5.3 Opportunity 170
8 Pipeline Assessment 172
8.1 Overview 172
8.2 Clinical Trial Mapping 173
8.2.1 Clinical Trials by Class 173
8.3 Promising Drugs in Clinical Development 174
8.3.1 Biopharmaceutical Products 176
8.3.2 Small Molecule 209
8.3.3 Other Drugs in Development 258
9 Current and Future Players 260
9.1 Overview 260
9.2 Trends in Corporate Strategy 261
9.3 Company Profiles 262
9.3.1 Actavis 262
9.3.2 Lundbeck 265
9.3.3 Eisai 268
9.3.4 Pfizer 270
9.3.5 Novartis 272
9.3.6 Roche 274
9.3.7 Eli Lilly 276
9.3.8 Merck & Co. 280
9.3.9 AstraZeneca 281
9.3.10 Takeda 283
10 Market Outlook 286
10.1 Global Markets 286
10.1.1 Forecast 286
10.1.2 Drivers and Barriers – Global Issues 294
10.2 United States 297
10.2.1 Forecast 297
10.2.2 Key Events 301
10.2.3 Drivers and Barriers 302
10.3 France 305
10.3.1 Forecast 305
10.3.2 Key Events 308
10.3.3 Drivers and Barriers 309
10.4 Germany 312
10.4.1 Forecast 312
10.4.2 Key Events 315
10.4.3 Drivers and Barriers 315
10.5 Italy 317
10.5.1 Forecast 317
10.5.2 Key Events 321
10.5.3 Drive
.....


【日本語目次(※自動翻訳出力)】

※以下は、Microsoft社の翻訳システムを使用した自動翻訳結果です。レイアウト崩れと不自然な日本語表現が多く表示されます。

。。。(後略)

【レポート販売概要】

■ タイトル:アルツハイマー病治療薬の世界市場予測および分析
■ 英文:PharmaPoint: Alzheimer’s Disease - Global Drug Forecast and Market Analysis to 2023 - Event-Driven Update
■ 発行日:2015年5月1日
■ 調査会社:GlobalData
■ 商品コード:GDHC010EPIDR
■ 調査対象地域:グローバル

▼当市場調査レポートの詳細内容確認、お問い合わせ及びご購入申込は下記ページでお願いします。▼
アルツハイマー病治療薬の世界市場予測および分析 (PharmaPoint: Alzheimer’s Disease - Global Drug Forecast and Market Analysis to 2023 - Event-Driven Update / GDHC010EPIDR)

  • 移動体通信事業者(MNO)のM2M戦略(Mobile Network Operator Machine-to-Machine (M2M) Strategies)
    Machine to Machine (M2M) is unleashing a wave of new possibilities for data gathering, predictive analytics and automation. M2M can be employed in various mundane yet important tasks in virtually every industry/segment including healthcare, telematics, asset management, surveillance, power grid, connected home, connected car and much more. M2M services are a key part of every successful enterprise …
  • 航空機キャビン照明の世界市場予測:標識用照明、ラバトリー照明、読書灯、天井灯、壁付灯、プフロアライトストリップ
    The aircraft cabin lighting market is projected to grow from USD 1.89 Billion in 2016 to USD 2.43 Billion by 2021, at a CAGR of 5.08% from 2016 to 2021. The aircraft cabin lighting market is growing due to the rise in aircraft deliveries, increase in low cost carriers and domestic civil aviation, growing need for fuel efficient aircraft, as well as increasing use of effective alternatives for the …
  • ベビー用食品・飲料の世界市場2016-2026
    The latest report from business intelligence provider visiongain offers comprehensive analysis of the global baby food & drink market. Visiongain assesses that this market will generate revenues of $59.36bn in 2016. Now: “Banker turned baby food maker sees start-up success”. This is an example of the business critical headline that you need to know about - and more importantly, you need to read vi …
  • 世界の量子ドット市場動向(2014-2018)
    TechNavio’s analysts forecast the Global Quantum Dots market will grow at a CAGR of 69.7 percent over the period 2013-2018. One of the key factors contributing to this market growth is the high performance and cost benefits of quantum dots. The Global Quantum Dots market has also been witnessing the increasing adoption for optoelectronic devices. However, the high cost of quantum dots could pose a …
  • 企業向けファイル共有・同期(EFSS)の世界市場2016-2020
    About EFSS Enterprises began using EFSS solutions with the increasing use of cloud computing, expanding network bandwidth, and collaboration of multi-regional businesses. EFSS solutions offer a centralized content storage repository for enterprise file sharing and collaboration, and allow users to save files in the cloud or on-premises storage and access them on other computing or mobile devices. …
  • 世界のSyrups & Spreads市場におけるニュース・イベント動向(2014年2月)
    Synopsis The report provides a review of the latest news and key events in the global syrups & spreads market during February 2014. Summary Using this report, marketers will effectively gain an insight into the latest happenings in the global syrups & spreads market throughout the month. The monthly report provides the reader with the top-line data necessary to quickly keep abreast of latest event …
  • ナノ印刷技術装置の世界市場2016-2020
    About the Global Nanolithography Equipment Market Nanolithography is the art and science of using lithographic techniques — like photolithography, nanoimprint lithography, X-ray lithography, and extreme ultraviolet (EUV) lithography — to produce nanostructures and devices. Nanolithography equipment is used to print complex nanometer-scale circuit patterns onto silicon wafers. This printing process …
  • 世界のSCARAロボット市場動向(2012-2016)
    TechNavio’s analysts forecast the Global SCARA Robot market to grow at a CAGR of 4.15 percent over the period 2012-2016. One of the key factors contributing to this market growth is the increased adoption in the assembly process. The Global SCARA Robot market has also been witnessing the emergence of next-generation SCARA robots. However the increasing threat of cross industry vendors could pose a …
  • ホワイトボックスサーバの世界市場予測(~2022年):ラックサーバ、タワーサーバ、ブレードサーバ、密度最適化サーバー
    The white box server market is expected to reach USD 14.43 Billion by 2022, at a CAGR of 18.6% between 2016 and 2022. The growth of this market is propelled by the factors such as low cost and high degree of customization, growing number of data centers, increasing adoption of white box servers among end users, growing number of data centers, rising adoption of open platforms such as Open Compute …
  • 大腸内視鏡の世界市場2017-2021
    ABSTRACTAbout Colonoscopy Devices Colonoscopy is an endoscopic examination of the large intestine and the distal part of the small bowel by using a charge-coupled device (CCD) camera or a fiberoptic camera on a flexible tube passed through the anus. Colonoscopy is considered as the gold standard of colorectal cancer screening. According to the Centers for Disease Control and Prevention (CDC) stati …
  • 天然繊維複合材料の世界市場
    The natural fiber composites market is projected to register a CAGR of 12.31% between 2014 and 2019 to reach $5,838.99 million by 2019. North America held the largest share in 2013 with the U.S. being the leading country. In the less explored markets of Asia-Pacific and Oceania, high growth is expected while the highly developed North American and European regions are predicted to show moderate to …
  • Immunotherapy Development Strategies – An Evolving Market with Significant Potential but with Challenging Hurdles to Overcome
    Although immunotherapy was first recognized over 100 years ago, it has only become an important therapeutic tool in recent decades. The immune system can be harnessed in one of several ways to tackle various diseases such as cancer, infection, auto-immune disease and inflammatory diseases. The complexity of the immune system has led to some intrinsic obstacles with clinical research, particularly …
  • イギリスの手術室用装置市場見通し(~2021)
    United Kingdom Operating Room Equipment Market Outlook to 2021 Summary GlobalData’s new report, "United Kingdom Operating Room Equipment Market Outlook to 2021", provides key market data on the United Kingdom Operating Room Equipment market. The report provides value, in millions of US dollars, volume (in units) and average price data (in US dollars), within market segments - Operating Room Tables …
  • 廃炉の世界市場:PWR原子炉、BWR原子炉、PHWR原子炉、LWGR原子炉、GCR原子炉
    Technavio’s research analyst predicts the global nuclear decommissioning market to grow at a CAGR over 2% during the forecast period. Fatal accidents such as the Chernobyl and Fukushima incidents have propelled the growth of this market. This has resulted in an increase in the decommissioning of nuclear plants across the globe. For instance, during 2011, Germany decided to phase out all its operat …
  • ガスタービンの世界市場予測および動向(~2020)
    The global gas turbines market is projected to grow at a CAGR of 3.9% from 2015 to 2020, to reach a value of USD 19.6 Billion by 2020. Increasing availability of natural gas owing to the shale gas boom and higher efficiency & lower carbon emission characteristics of natural gas-fired power plants are the major factors driving the gas turbines market. Applications of gas turbines are not limited to …
※当サイトは世界の市場調査レポート紹介サイトです。市場規模、市場動向、市場予測など、多様な分析データを含むグローバル調査レポートをご案内致します。日本国内を含むアジア太平洋、中国、ヨーロッパ、アメリカ、北米、中南米、中東、アフリカ地域などにおける、製品、サービス、技術、企業(メーカー、ベンダー)、市場シェア、市場環境など多様な項目に対応致します。当サイトでご紹介するレポートは「市場調査レポート販売サイトのMarketReport.jp」でお問い合わせ及びご購入可能です。