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【英文タイトル】Kinase Inhibitors for Cancer Treatment: World Industry Analysis, R&D and Market Forecasts 2015-2025
: Explore the Potentials of New Drugs

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【レポートの概要(一部)】

1. Report Overview
1.1 Overview of the Protein Kinase Inhibitor Market for Cancer Treatments, 2015
1.2 Benefits of This Report
1.2.1 How This Report Delivers
1.2.2 Main Questions Answered by this Analytical Study
1.3 Who is This Report For?
1.4 Methods of the Study
1.5 Frequently Asked Questions (FAQ)
1.6 Associated Visiongain Reports
1.7 About Visiongain

2. Introduction to Anti-Cancer Kinase Inhibitors
2.1 What are Protein Kinases and Protein Kinase Inhibitors?
2.2 Protein Kinases in Oncology
2.3 Glossary

3. Leading Anti-Cancer Kinase Inhibitor Drugs: Forecasts and Discussions, 2015-2025
3.1 Brc-Abl Inhibitors – Transforming Chronic Myeloid Leukaemia from a Fatal Diagnosis To a Managed Lifestyle
3.1.1 Glivec/Gleevec (imatinib) – Novartis
3.1.2 Sprycel (dasatinib) – Bristol-Myers Squibb
3.1.3 Tasigna (nilotinib) – Novartis
3.1.4 Bosulif (bosutinib) – Pfizer
3.1.5 Iclusig (ponatinib) – ARIAD Pharmaceuticals
3.2 EGFR Inhibitors Target a Mutation-Positive Market
3.2.1 Tarceva (erlotinib) – Roche/Astellas
3.2.2 Iressa (gefinitib) – AstraZeneca
3.2.3 Gilotrif/Giotrif (afatinib) – Boehringer Ingelheim
3.3 Angiogenesis Inhibitors Have a Variety of Indications
3.3.1 Nexavar (sorafenib) – Bayer/Onyx
3.3.2 Sutent (sunitinib) – Pfizer
3.3.3 Votrient (pazopanib) – Novartis
3.3.4 Inlyta (axitinib) – Pfizer
3.4 BRAF and MEK Inhibitors: A Promising Combination
3.4.1 Zelboraf (vemurafenib) – Roche
3.4.2 Mekinist (trametinib) and Tafinlar (dabrafenib) – Novartis
3.5 mTOR Inhibitors Have a New Entrant
3.5.1 Afinitor/Votubia (everolimus) – Novartis
3.5.2 Torisel (temsirolimus) – Pfizer
3.5.3 Zydelig (idelalisib) – Gilead Sciences
3.6 Other Leading Cancer Inhibitors Are a Varied Group
3.6.1 Imbruvica (ibrutinib) – J&J/Pharmacyclics/AbbVie
3.6.2 Jakavi/Jakafi (ruxolitinib) – Novartis/Incyte
3.6.3 Xalkori (crizotinib) – Pfizer
3.6.4 Cometriq (cabozantinib) – Exelixis
3.6.5 Caprelsa (vandetanib) – AstraZeneca
3.6.6 Tyverb/Tykerb (lapatinib) – Novartis
3.6.7 Stivarga (regorafenib) – Bayer
3.6.8 Zykadia (ceritinib, LDK378) – Novartis
3.6.9 Ibrance (palbociclib) – Pfizer
3.6.10 Alectinib (AF802) – Roche

4. Anti-Cancer Kinase Inhibitors: World Market Outlook and Forecast, 2015-2025
4.1 Global Anti-Cancer Kinase Inhibitors Market: Leading Kinase Inhibitors in 2014
4.2 World Anti-Cancer Kinase Inhibitors Market: Revenue Forecasts and Change in Market Shares by Class 2015-2025
4.3 Bcr-Abl Inhibitors Lead the Anti-Cancer Kinase Inhibitors Market in 2015
4.3.1 Drivers and Restraints of the Bcr-Abl Kinase Inhibitors Market 2015-2025
4.4 Novel Kinase Inhibitors Will Dominate the Market As They Cover a Broad Range
4.4.1 Drivers and Restraints of these Other Kinase Inhibitors 2015-2025

5. Leading National Markets for Anti-Cancer Kinase Inhibitors, 2015-2025
5.1 Regional Breakdown of the Global Anti-Cancer Kinase Inhibitors Market, 2014
5.2 World Anti-Cancer Kinase Inhibitors Market: Regional Forecast 2015-2025
5.3 How Will Regional Market Shares Change through to 2025?
5.4 The US Anti-Cancer Kinase Inhibitors Market Forecast 2015-2025
5.4.1 Drivers and Restraints of the US Anti-Cancer Kinase Inhibitors Market 2015-2025
5.5 The EU Anti-Cancer Kinase Inhibitors Market 2015-2025
5.5.1 Drivers and Restraints of the EU Anti-Cancer Kinase Inhibitors Market 2015-2025
5.5.2 German Anti-Cancer Kinase Inhibitors Market Forecast 2015-2025
5.5.3 French Anti-Cancer Kinase Inhibitors Market Forecast 2015-2025
5.5.4 Italian Anti-Cancer Kinase Inhibitors Market Forecast 2015-2025
5.5.5 UK Anti-Cancer Kinase Inhibitors Market Forecast 2015-2025
5.5.6 Spanish Anti-Cancer Kinase Inhibitors Market Forecast 2015-2025
5.6 Japanese Anti-Cancer Kinase Inhibitors Market Forecast 2015-2025
5.7 The Anti-Cancer Kinase Inhibitors Emerging Market: BRIC 2015-2025
5.7.1 China: Anti-Cancer Kinase Inhibitors Market Forecast 2015-2025
5.7.2 India: Anti-Cancer Kinase Inhibitors Market Forecast 2015-2025
5.7.3 Brazil: Anti-Cancer Kinase Inhibitors Market Forecast 2015-2025
5.7.4 Russia: Anti-Cancer Kinase Inhibitors Market Forecast 2015-2025

6. Anti-Cancer Kinase Inhibitors: R&D Pipeline, 2015
6.1 Cyclin-Dependent Kinase 4/6 Inhibitors in Development
6.1.1 LEE-011 – Novartis
6.1.2 Abemaciclib (LY2835219) – Eli Lilly
6.2 ALK Inhibitors in Development
6.2.1 Brigatinib (AP26113) – ARIAD Pharmaceuticals
6.3 Bruton’s Tyrosine Kinase and PI3K Inhibitors in Development
6.3.1 Venetoclax (ABT-199/RG7601/GDC-0199)– Roche/AbbVie
6.3.2 Duvelisib (IPI-145) – Infinity Pharmaceuticals/AbbVie
6.3.3 Buparlisib (BKM120) – Novartis
6.3.4 ONO-4059 – ONO Pharmaceutical/Gilead Sciences
6.3.5 Copanlisib (BAY 80-6946) – Bayer
6.3.6 Pictilisib (GDC-0941/RG7321) – Roche
6.3.7 BEZ235 – Novartis
6.4 MEK and BRAF Inhibitors in Development
6.4.1 Cobimetinib (GDC-0973/XL518) – Exelixis/Roche
6.4.2 Encorafenib (LGX818) & Binimetinib (MEK162)– Array BioPharma
6.4.3 Selumetinib (AZD 6244) – AstraZeneca/Array BioPharma
6.5 Other Anti-Cancer Kinase Inhibitors in Development
6.5.1 Volasertib – Boehringer Ingelheim
6.5.2 Neratinib (PB272) – Puma Biotechnology
6.5.3 Tivantinib (ARQ197) – Daiichi Sankyo/ArQule
6.5.4 Dovitinib (TKI258) – Novartis
6.5.5 Dacomitinib – Pfizer
6.5.6 Rociletinib (CO-1686) – Clovis Oncology
6.5.7 Entrectinib (RXDX-101) – Ignyta
6.5.8 INC280 and EGF816 – Novartis

7. Leading Companies in the Anti-Cancer Kinase Inhibitors Market, 2015
7.1 Leading Companies in the Anti-Cancer Kinase Inhibitors Market by Revenue, 2014
7.1.1 Leading Anti-Cancer Kinase Inhibitors Manufacturers: Revenue Forecasts, 2015-2025
7.2 Leading Anti-Cancer Kinase Inhibitor Company Profiles
7.2.1 Novartis: Interesting Developments and a Continued Lead on the Market
7.2.2 Pfizer: Advancing Closer to Novartis’ Lead
7.2.3 Roche: A Global Giant in Cancer Treatment
7.2.4 Bristol-Myers Squibb’s Success is Tied to Sprycel
7.2.5 Bayer Healthcare: Nexavar and Stivarga
7.2.6 AstraZeneca Needs the US Market To Succeed
7.2.7 Gilead Sciences
7.3 Other Companies
7.3.1 AbbVie
7.3.2 Boehringer Ingelheim BioXcellence

8. Qualitative Analysis of the Anti-Cancer Kinase Inhibitors Market, 2015-2025
8.1 SWOT Analysis of the Anti-Cancer Kinase Inhibitors Market
8.2 Strengths
8.2.1 Personalised Medicine is a Strong Trend in Cancer Treatment
8.2.2 Targeted Kinase Inhibitors are Generally Well-Tolerated
8.2.3 Strong Pipeline of Novel Inhibitors Will Drive Market Growth
8.2.4 Oral Dosage is the Preferred Treatment
8.3 Weaknesses
8.3.1 High-Cost of Treatment May Restrain the Market
8.3.2 Ease of Manufacturing Small Molecule Drugs
8.3.3 Monoclonal Antibodies are More Specific than Small Molecules
8.4 Opportunities
8.4.1 Ageing Populations and Rising Cancer Prevalence Will Increase Demand for Treatment
8.4.2 Investment into Research May Lead to Improved Targeted Treatments
8.4.3 Combination Therapies Bring Additive Benefits
8.5 Threats
8.5.1 Regulations: Can they Restrain the Market?
8.5.2 Multiple Companies Competing
8.6 STEP Analysis of the Anti-Cancer Kinase Inhibitors Market

9. Research Interviews
9.1 Interview with Dr Lawrence Bloch, Chief Finance and Business Officer, Infinity Pharmaceuticals, United States
9.1.1 Positioning a Novel Therapeutic in Blood Cancer Indications
9.1.2 Combining Therapies Offers Significant Benefit to Patients
9.1.3 Potential in Rheumatoid Arthritis and Blood Cancers
9.2 Interview with Dr Marcel Spaargaren, Associate Professor, LYMMCARE (Lymphoma and Myeloma Center Amsterdam)
9.2.1 Combining Two Kinase Inhibitor Therapeutics
9.2.2 Expectations for Kinase Inhibitor Therapies as Cancer Treatments
9.2.3 The Future of B-Cell Receptor Inhibitors

10. Conclusions from the Research and Analysis
10.1 World Anti-Cancer Kinase Inhibitors Market: Outlook from 2015
10.1.1 Recent Launches of Innovative Drugs and a Robust Pipeline Will Drive Market Growth
10.2 Opportunities in Developed and Developing National Pharma Markets Expanding Those Drug Sales


【レポート販売概要】

■ タイトル:がん治療用キナーゼ阻害剤の世界市場
■ 英文:Kinase Inhibitors for Cancer Treatment: World Industry Analysis, R&D and Market Forecasts 2015-2025
: Explore the Potentials of New Drugs
■ 発行日:2015年8月
■ 調査会社:visiongain
■ 商品コード:VGAIN5081916
■ 調査対象地域:グローバル
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