【レポートの概要（一部）】
1 Table of Contents
1 Table of Contents 5
1.1 List of Tables 7
1.2 List of Figures 8
2 Monoclonal Antibodies Market in Breast Cancer to 2019 – Introduction 9
2.1 Symptoms 9
2.2 Etiology 9
2.3 Epidemiology 10
2.4 Pathophysiology 10
2.5 Diagnosis 11
2.6 Prognosis and Disease Staging 11
2.6.1 Classification 13
2.7 Treatment Options 13
2.7.1 Surgery and Radiation Therapy 13
2.7.2 Chemotherapy 14
2.7.3 Hormonal Therapies 15
2.7.4 Targeted Therapies 15
2.7.5 Resistance to Pharmacological Therapies 16
2.7.6 Treatment Guidelines 17
2.7.7 Measuring the Effectiveness of Treatment 19
3 Marketed Products 20
3.1 Herceptin (Trastuzumab) – Hoffmann La Roche 20
3.2 Avastin (Bevacizumab) – Hoffmann La Roche 23
3.3 Kadcyla (Trastuzumab Emtansine) – Hoffmann La Roche 25
3.4 Perjeta (Pertuzumab) – Hoffmann La Roche 26
3.5 Xgeva (denosumab) – Amgen 27
3.6 Heat Map for Marketed Products 28
3.7 Conclusion 30
4 Pipeline for Breast Cancer Monoclonal Antibody Therapeutics 31
4.1 Overall Pipeline 32
4.2 Mechanisms of Action 34
4.3 Clinical Trials 37
4.3.1 Attrition Rate 37
4.3.2 Clinical Trial Size 38
4.3.3 Duration 40
4.3.4 Clinical Trial End-points 42
4.4 Promising Drug Candidates in the Pipeline 44
4.4.1 CDX-011 (glembatumumab vedotin) – Celldex Therapeutics 44
4.4.2 Metmab (onartuzumab) – Hoffman La Roche 44
4.4.3 Hu3S193 – Recepta Biopharma 44
4.4.4 MM-121 – Merrimack Pharmaceuticals 45
4.4.5 IMC-18F1 (Icrucumab) – Eli Lilly 45
4.4.6 Rexomun (Ertumaxomab) – Fresenius Biotech 45
4.4.7 Medi-573 (Dusigitumab) – Medimmune 45
4.4.8 MK-0646 (Dalotuzumab) – Merck and Co 46
4.4.9 LY3012217 (Cixutumumab) – Eli Lilly 46
4.5 Conclusion 46
5 Market Forecast to 2019 48
5.1 Global 48
5.1.1 Treatment Usage Patterns 48
5.1.2 Market Size 49
5.2 US 50
5.2.1 Treatment Usage Patterns 50
5.2.2 Market Size 51
5.3 Canada 52
5.3.1 Treatment Usage Patterns 52
5.3.2 Market Size 53
5.4 Europe 54
5.4.1 Treatment Usage Patterns 54
5.4.2 Annual Cost of Therapy 55
5.4.3 Market Size 56
5.5 Japan 57
5.5.1 Treatment Usage Patterns 57
5.5.2 Market Size 58
5.6 Drivers and Barriers 59
5.6.1 Drivers 59
5.6.2 Barriers 59
6 Deals and Strategic Consolidations 60
6.1 R&D Licensing Agreements 60
6.1.1 Key Licensing Deals 63
6.2 Co-development Agreements 65
6.2.1 Key Deals 65
7 Appendix 68
7.1 References 68
7.2 References for Heat Map 73
7.3 All Pipeline Products, by Phase 74
7.3.1 Discovery 74
7.3.2 Preclinical 77
7.3.3 IND/CTA Filed and Phase I 89
7.3.4 Phase II 95
7.3.5 Phase III and Pre-Registration 102
7.4 Market Definitions 104
7.5 Abbreviations 105
7.6 Tabular Forecast Data 106
7.6.1 Global 106
7.6.2 US 106
7.6.3 Canada 106
7.6.4 UK 107
7.6.5 France 107
7.6.6 Germany 107
7.6.7 Italy 107
7.6.8 Spain 108
7.6.9 Japan 108
7.7 Research Methodology 109
7.7.1 Coverage 109
7.7.2 Secondary Research 109
7.8 Therapeutic Landscape 110
7.9 Epidemiology-Based Forecasting 110
7.10 Market Size by Geography 111
7.11 Geographical Landscape 112
7.12 Pipeline Analysis 112
7.13 Competitive Landscape 112
7.13.1 Expert Panel Validation 112
7.14 Contact Us 112
7.15 Disclaimer 112
【レポート販売概要】
■ タイトル：Monoclonal Antibodies Market in Breast Cancer to 2019 – Strong Uptake of Novel HER-2 Targeted Therapies to Drive Robust Growth■ 発行日：2013年10月31日
■ 調査会社：GBI Research
■ 商品コード：GBIR403170039
■ 調査対象地域：グローバル
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