【レポートの概要（一部）】
Table of Contents
Table of Contents 2
List of Tables 8
List of Figures 9
Introduction 10
Global Markets Direct Report Coverage 10
Peripheral Artery Occlusive Disease (PAOD) Overview 11
Therapeutics Development 12
Pipeline Products for Peripheral Artery Occlusive Disease (PAOD) – Overview 12
Pipeline Products for Peripheral Artery Occlusive Disease (PAOD) – Comparative Analysis 13
Peripheral Artery Occlusive Disease (PAOD) – Therapeutics under Development by Companies 14
Peripheral Artery Occlusive Disease (PAOD) – Pipeline Products Glance 18
Late Stage Products 18
Clinical Stage Products 19
Early Stage Products 20
Unknown Stage Products 21
Peripheral Artery Occlusive Disease (PAOD) – Products under Development by Companies 22
Peripheral Artery Occlusive Disease (PAOD) – Companies Involved in Therapeutics Development 26
Annexin Pharmaceuticals AB 26
Apceth GmbH & Co. KG 27
AstraZeneca PLC 28
Athersys, Inc. 29
Bayer AG 30
Betagenon AB 31
Cardiolynx AG 32
CardioVascular BioTherapeutics, Inc. 33
Celgene Corporation 34
Cytokinetics, Inc. 35
Diffusion Pharmaceuticals LLC 36
DNAVEC Corporation 37
Genovate Biotechnology Co., LTD. 38
Grifols, S.A. 39
Human Stem Cells Institute 40
Kowa Company, Ltd. 41
Lacer, S.A. 42
Ligand Pharmaceuticals, Inc. 43
LTT Bio-Pharma Co., Ltd. 44
miRagen Therapeutics, Inc. 45
Multi Gene Vascular Systems Ltd 46
Nuo Therapeutics, Inc. 47
Pluristem Therapeutics Inc. 48
Proteon Therapeutics, Inc. 49
Recardio GmbH 50
RegenoCELL Therapeutics, Inc. 51
Rigel Pharmaceuticals, Inc. 52
Sagene Pharmaceuticals, Inc. 53
Stemedica Cell Technologies, Inc. 54
Taisho Toyama Pharmaceutical Co., Ltd. 55
Theravasc, Inc. 56
vasopharm GmbH 57
ViroMed Co., Ltd. 58
Peripheral Artery Occlusive Disease (PAOD) – Therapeutics Assessment 59
Assessment by Monotherapy Products 59
Assessment by Combination Products 60
Assessment by Target 61
Assessment by Mechanism of Action 63
Assessment by Route of Administration 65
Assessment by Molecule Type 67
Drug Profiles 69
(cilostazol + organic nitrate) ER – Drug Profile 69
Product Description 69
Mechanism of Action 69
R&D Progress 69
AEM-28 – Drug Profile 70
Product Description 70
Mechanism of Action 70
R&D Progress 70
ALD-301 – Drug Profile 71
Product Description 71
Mechanism of Action 71
R&D Progress 71
Alecmestencel-T – Drug Profile 73
Product Description 73
Mechanism of Action 73
R&D Progress 73
alprostadil – Drug Profile 74
Product Description 74
Mechanism of Action 74
R&D Progress 74
Annexin A-5 – Drug Profile 75
Product Description 75
Mechanism of Action 75
R&D Progress 75
AP-01 – Drug Profile 77
Product Description 77
Mechanism of Action 77
R&D Progress 77
cilostazol CR – Drug Profile 78
Product Description 78
Mechanism of Action 78
R&D Progress 78
clopidogrel bisulfate – Drug Profile 79
Product Description 79
Mechanism of Action 79
R&D Progress 79
CVBT-141C – Drug Profile 80
Product Description 80
Mechanism of Action 80
R&D Progress 80
DVC1-0101 – Drug Profile 81
Product Description 81
Mechanism of Action 81
R&D Progress 81
ELS-140 – Drug Profile 82
Product Description 82
Mechanism of Action 82
R&D Progress 82
Gene Therapy for Critical Limb Ischemia and Peripheral Arterial Disease – Drug Profile 83
Product Description 83
Mechanism of Action 83
R&D Progress 83
Gene Therapy to Activate Vascular Endothelial Growth Factor for Cardiovascular Disease and Central Nervous System Disorders – Drug Profile 84
Product Description 84
Mechanism of Action 84
R&D Progress 84
Human Plasmin – Drug Profile 85
Product Description 85
Mechanism of Action 85
R&D Progress 85
K-134 – Drug Profile 87
Product Description 87
Mechanism of Action 87
R&D Progress 87
LA-419 – Drug Profile 88
Product Description 88
Mechanism of Action 88
R&D Progress 88
LT-0101 – Drug Profile 89
Product Description 89
Mechanism of Action 89
R&D Progress 89
Mesenchymal Stem Cells – Drug Profile 90
Product Description 90
Mechanism of Action 90
R&D Progress 90
MGN-6114 – Drug Profile 92
Product Description 92
Mechanism of Action 92
R&D Progress 92
MultiGeneAngio – Drug Profile 93
Product Description 93
Mechanism of Action 93
R&D Progress 93
MultiGeneGraft – Drug Profile 94
Product Description 94
Mechanism of Action 94
R&D Progress 94
MultiStem – Drug Profile 95
Product Description 95
Mechanism of Action 95
R&D Progress 95
O-304 – Drug Profile 98
Product Description 98
Mechanism of Action 98
R&D Progress 98
PDA-002 – Drug Profile 99
Product Description 99
Mechanism of Action 99
R&D Progress 99
R-118 – Drug Profile 100
Product Description 100
Mechanism of Action 100
R&D Progress 100
REC-03 – Drug Profile 101
Product Description 101
Mechanism of Action 101
R&D Progress 101
rivaroxaban – Drug Profile 102
Product Description 102
Mechanism of Action 102
R&D Progress 102
selegiline + Antiplatelet Drugs – Drug Profile 107
Product Description 107
Mechanism of Action 107
R&D Progress 107
sodium nitrite – Drug Profile 108
Product Description 108
Mechanism of Action 108
R&D Progress 108
Stem Cell Therapy for Cardiovascular Diseases – Drug Profile 110
Product Description 110
Mechanism of Action 110
R&D Progress 110
Stem Cell Therapy for Cardiovascular Diseases – Drug Profile 112
Product Description 112
Mechanism of Action 112
R&D Progress 112
SYN-20112312RU – Drug Profile 113
Product Description 113
Mechanism of Action 113
R&D Progress 113
ticagrelor – Drug Profile 114
Product Description 114
Mechanism of Action 114
R&D Progress 114
tirasemtiv – Drug Profile 117
Product Description 117
Mechanism of Action 117
R&D Progress 117
transcrocetinate sodium – Drug Profile 123
Product Description 123
Mechanism of Action 123
R&D Progress 123
TXA-127 – Drug Profile 124
Product Description 124
Mechanism of Action 124
R&D Progress 124
VAS-2870 – Drug Profile 126
Product Description 126
Mechanism of Action 126
R&D Progress 126
VM-202 – Drug Profile 127
Product Description 127
Mechanism of Action 127
R&D Progress 127
vonapanitase – Drug Profile 129
Product Description 129
Mechanism of Action 129
R&D Progress 129
Peripheral Artery Occlusive Disease (PAOD) – Recent Pipeline Updates 130
Peripheral Artery Occlusive Disease (PAOD) – Dormant Projects 166
Peripheral Artery Occlusive Disease (PAOD) – Discontinued Products 171
Peripheral Artery Occlusive Disease (PAOD) – Product Development Milestones 173
Featured News & Press Releases 173
Feb 02, 2015: The Small molecule AMPK activator O304 acts as an oral PCSK9 inhibitor 173
Jan 08, 2015: Journal of Cardiovascular Pharmacology Publishes Positive Nonclinical Results of Proteon Therapeutics’ PRT-201 in Peripheral Artery Disease 173
Sep 29, 2014: Annexin Pharmaceuticals Announces Patent 174
Sep 02, 2014: Capstone Therapeutics Announces Phase 1a Results for AEM-28 Showing Safety and Biomarker Efficacy Signals 174
Jul 09, 2014: Development Of Russian Innovative Drug For Peripheral Arterial Disease Is Supported By The Council Of Maryland Biotech Companies (USA) 175
Mar 17, 2014: AstraZeneca Announces Progress on Global PARTHENON Clinical Trial Program with BRILINTA in High-Risk Cardiovascular Disease Patient Populations in Advance of American College of Cardiology Scientific Session 176
Mar 06, 2014: Rigel Announces Publication of R118 AMPK Activator Research 178
Nov 13, 2013: Pluristem Receives Regulatory Approval to Extend Its Phase II Study of PLX-PAD Cells in the Treatment of Intermittent Claudication to South Korea 179
Oct 02, 2013: Pluristem Receives Israeli Ministry of Health Approval to Expand Its Phase II Clinical Trial in Intermittent Claudication to Israel 180
Sep 16, 2013: FDA Lifts Clinical Hold of Pluristem’s Phase II Intermittent Claudication Study 180
Appendix 181
Methodology 181
Coverage 181
Secondary Research 181
Primary Research 181
Expert Panel Validation 181
Contact Us 181
Disclaimer 182
【レポート販売概要】
■ タイトル：末梢動脈閉塞性疾患(Peripheral Artery Occlusive Disease (PAOD))：治療薬開発パイプライン動向（2015年上半期版）■ 英文：Peripheral Artery Occlusive Disease (PAOD) - Pipeline Review, H1 2015
■ 発行日：2015年3月11日
■ 調査会社：Global Markets Direct
■ 商品コード：GMDHC6257IDB
■ 調査対象地域：グローバル
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