【レポートの概要（一部）】
1 Table of Contents
1 Table of Contents 12
1.1 List of Tables 19
1.2 List of Figures 24
2 Introduction 26
2.1 Catalyst 26
2.2 Related Reports 27
2.3 Upcoming Related Reports 27
3 Disease Overview 28
3.1 Etiology and Pathophysiology 28
3.1.1 Etiology 28
3.1.2 Pathophysiology 29
3.2 Symptoms 30
3.3 Classification of Atrial Fibrillation 31
3.4 Prognosis 32
4 Epidemiology 33
4.1 Disease Background 33
4.2 Risk Factors and Comorbidities 34
4.3 Global Trends 36
4.4 Forecast Methodology 38
4.4.1 Sources Used 40
4.4.2 Forecast Assumptions and Methods 46
4.4.3 Sources Not Used 51
4.5 Epidemiological Forecast for Atrial Fibrillation (2013-2023) 52
4.5.1 Diagnosed Prevalent Cases of Atrial Fibrillation 52
4.5.2 Age-Specific Diagnosed Prevalent Cases of Atrial Fibrillation 53
4.5.3 Sex-Specific Diagnosed Prevalent Cases of Atrial Fibrillation 55
4.5.4 Age-Standardized Diagnosed Prevalence of Atrial Fibrillation 57
4.5.5 Diagnosed Prevalent Cases of Atrial Fibrillation by Clinical Subtypes 59
4.6 Discussion 60
4.6.1 Epidemiological Forecast Insight 60
4.6.2 Limitations of the Analysis 62
4.6.3 Strengths of the Analysis 63
5 Disease Management 64
5.1 Diagnosis and Treatment Overview 64
5.1.1 Diagnosis 64
5.1.2 Treatment Guidelines and Leading Prescribed Drugs 66
5.1.3 Clinical Practice 68
5.2 US 82
5.3 France 84
5.4 Germany 86
5.5 Italy 88
5.6 Spain 90
5.7 UK 92
5.8 Japan 94
5.9 Canada 97
6 Competitive Assessment 99
6.1 Overview 99
6.2 Product Profiles – Major Brands, Anticoagulant Agents 104
6.2.1 Warfarin (Widely Genericized) 104
6.2.2 Pradaxa (dabigatran) 114
6.2.3 Xarelto (rivaroxaban) 128
6.2.4 Eliquis (apixaban) 141
6.2.5 Savaysa (edoxaban) 154
6.3 Product Profiles – Major Brands, Antiarrhythmic Drugs 166
6.3.1 Multaq (dronedarone) 166
6.3.2 Brinavess (vernakalant) 178
6.4 Other Therapeutic Classes 190
6.4.1 Vitamin K Antagonists Other than Warfarin (Widely Genericized) 191
6.4.2 Antiplatelets – Aspirin (Widely Genericized) 193
6.4.3 Beta-Blockers – Atenolol, Metoprolol, Propranolol (Widely Genericized) 194
6.4.4 Calcium Channel Blockers – Diltiazem, Verapamil (Widely Genericized) 195
6.4.5 Cardiac Glycosides − Digoxin (Widely Genericized) 196
6.4.6 Potassium Channel Blockers – Amiodarone, Sotalol, Dofetilide (Widely Genericized) 197
6.4.7 Sodium Channel Blockers – Flecainide, Propafenone (Widely Genericized) 199
7 Unmet Need and Opportunity 201
7.1 Overview 201
7.2 Safer Antiarrhythmic Drugs for the Maintenance of Sinus Rhythm 202
7.2.1 Unmet Need 202
7.2.2 Gap Analysis 203
7.2.3 Opportunity 204
7.3 Effective and Rapid Acting Cardioversion Drugs 205
7.3.1 Unmet Need 205
7.3.2 Gap Analysis 206
7.3.3 Opportunity 207
7.4 Antidotes for the New Oral Anticoagulants 208
7.4.1 Unmet Need 208
7.4.2 Gap Analysis 209
7.4.3 Opportunity 211
7.5 Improved Access to and Reimbursement of the New Oral Anticoagulants 212
7.5.1 Unmet Need 212
7.5.2 Gap Analysis 215
7.5.3 Opportunity 217
7.6 Increased Physician Education on the Clinical Benefits of the NOACs 218
7.6.1 Unmet Need 218
7.6.2 Gap Analysis 219
7.6.3 Opportunity 220
7.7 Increased Patient Awareness on the Clinical Benefits of the NOACs 221
7.7.1 Unmet Need 221
7.7.2 Gap Analysis 222
7.7.3 Opportunity 222
8 Pipeline Assessment 224
8.1 Overview 224
8.2 Clinical Trial Mapping 225
8.2.1 Clinical Trials by Country 225
8.2.2 Clinical Trials by Phase and Trial Status 226
8.3 Promising Drugs in Clinical Development 227
8.3.1 Ranolazine/Dronedarone 229
8.3.2 Vanoxerine 239
8.4 Other Drugs in Development 249
8.4.1 Early-Stage Anticoagulant Pipeline 249
8.4.2 Early-Stage Antiarrhythmia Pipeline 255
9 Current and Future Players 260
9.1 Overview 260
9.2 Trends in Corporate Strategy 262
9.3 Company Profiles 264
9.3.1 Boehringer Ingelheim 264
9.3.2 Bayer 267
9.3.3 Janssen (Johnson & Johnson) 270
9.3.4 Bristol-Myers Squibb 273
9.3.5 Pfizer 276
9.3.6 Daiichi-Sankyo 280
9.3.7 Gilead 283
10 Market Outlook 286
10.1 Global Markets 286
10.1.1 Forecast 286
10.1.2 Drivers and Barriers – Global Issues 295
10.2 United States 300
10.2.1 Forecast 300
10.2.2 Key Events 306
10.2.3 Drivers and Barriers 306
10.3 France 309
10.3.1 Forecast 309
10.3.2 Key Events 313
10.3.3 Drivers and Barriers 313
10.4 Germany 317
10.4.1 Forecast 317
10.4.2 Key Events 322
10.4.3 Drivers and Barriers 322
10.5 Italy 324
10.5.1 Forecast 324
10.5.2 Key Events 329
10.5.3 Drivers and Barriers 329
10.6 Spain 332
10.6.1 Forecast 332
10.6.2 Key Events 336
10.6.3 Drivers and Barriers 336
10.7 United Kingdom 338
10.7.1 Forecast 338
10.7.2 Key Events 343
10.7.3 Drivers and Barriers 343
10.8 Japan 346
10.8.1 Forecast 346
10.8.2 Key Events 351
10.8.3 Drivers and Barriers 351
10.9 Canada 354
10.9.1 Forecast 354
10.9.2 Key Events 358
10.9.3 Drivers and Barriers 358
11 Appendix 361
11.1 Bibliography 361
11.2 Abbreviations 382
11.3 Methodology 387
11.4 Forecasting Methodology 387
11.4.1 Diagnosed Atrial Fibrillation Patients 387
11.4.2 Percent Drug-Treated Patients 388
11.4.3 Drugs Included in Each Therapeutic Class 388
11.4.4 Launch and Patent Expiry Dates 389
11.4.5 General Pricing Assumptions 390
11.4.6 Individual Drug Assumptions 391
11.4.7 Generic Erosion 400
11.4.8 Pricing of Pipeline Agents 400
11.5 Physicians and Specialists Included in this Study 401
11.6 About the Authors 403
11.6.1 Analyst 403
11.6.2 Therapy Area Director 403
11.6.3 Epidemiologist 404
11.6.4 Global Head of Healthcare 404
11.7 About GlobalData 405
11.8 Disclaimer 405
【レポート販売概要】
■ タイトル：心房細動治療薬の世界市場予測および分析■ 英文：PharmaPoint: Atrial Fibrillation - Global Drug Forecast and Market Analysis to 2023
■ 発行日：2015年2月27日
■ 調査会社：GlobalData
■ 商品コード：GDHC87PIDR
■ 調査対象地域：グローバル
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