医療レポート：Alzheimer’s Disease-疫学予測（～2022）...市場調査レポートについてご紹介

1 Table of Contents
1 Table of Contents 4
1.1 List of Tables 6
1.2 List of Figures 6
2 Introduction 7
2.1 Catalyst 7
3 Epidemiology 8
3.1 Risk Factors and Comorbidities 8
3.1.1 Family history of Alzheimer’s disease increases risk by 7.5 times 9
3.1.2 APOE ε4 allele triples the risk of Alzheimer’s disease 9
3.1.3 Cardiovascular risk factors increase the risk of Alzheimer’s disease by twofold 9
3.1.4 Incidence and prevalence of Alzheimer’s disease double every five years after age 65 10
3.1.5 Diabetes doubles the risk of Alzheimer’s in men, but only marginally increases the risk in women 10
3.1.6 Women are 1.5 times more likely to develop Alzheimer’s disease than men 11
3.1.7 Mild Cognitive Impairment (MCI) increases the risk of Alzheimer’s disease, but may be part of the causal pathway 11
3.1.8 Depression triples risk of Alzheimer’s disease and is the most common comorbidity 12
3.1.9 Up to 70% of Alzheimer’s disease patients also suffer from anxiety 12
3.1.10 Psychosis and agitation are common comorbidities among Alzheimer’s patients 13
3.2 Global Trends 13
3.2.1 United States 14
3.2.2 5EU 14
3.2.3 Japan 15
3.2.4 China 15
3.2.5 India 15
3.3 Forecast Methodology 16
3.3.1 Sources Used 17
3.3.2 Forecast Assumptions and Methods 21
3.3.3 Sources Not Used 23
3.4 Epidemiology Forecast (2012–2022) 23
3.4.1 Prevalent Cases of Alzheimer’s Disease 23
3.4.2 Age-Specific Prevalent Cases of Alzheimer’s Disease 25
3.4.3 Sex-Specific Prevalent Cases of Alzheimer’s Disease 26
3.4.4 Age-Standardized Prevalence of Alzheimer’s Disease 28
3.5 Discussion 29
3.5.1 Conclusions Regarding Epidemiological Trends 29
3.5.2 Limitations of the Analysis 31
3.5.3 Strengths of the Analysis 31
4 Appendix 32
4.1 Bibliography 32
4.2 About the Authors 37
4.2.1 Epidemiologists 37
4.2.2 Reviewers 38
4.2.3 Global Director of Epidemiology and Clinical Trials Analysis 39
4.2.4 Global Head of Healthcare 40
4.3 About GlobalData 41
4.4 About EpiCast 41
4.5 Contact Us 41
4.6 Disclaimer 42